Stock Based Compensation - Schedule of Total Stock-Based Compensation Expense from Stock Options and Warrants (Details) - Stock Options And Warrants [Member] - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2018	Jun. 30, 2017	Jun. 30, 2018	Jun. 30, 2017
Employees [Member]
Allocated employee and non-employee stock-based compensation expense, Total	$ 294,386	$ 680,353	$ 616,581	$ 1,501,101
Non Employees [Member]
Allocated employee and non-employee stock-based compensation expense, Total	19,517	36,578	40,867	65,237
Research and Development Expense [Member] | Employees [Member]
Allocated employee and non-employee stock-based compensation expense, Total	29,451	278,533	60,423	631,616
Research and Development Expense [Member] | Non Employees [Member]
Allocated employee and non-employee stock-based compensation expense, Total
General and Administrative Expense [Member] | Employees [Member]
Allocated employee and non-employee stock-based compensation expense, Total	264,935	401,820	556,158	869,485
General and Administrative Expense [Member] | Non Employees [Member]
Allocated employee and non-employee stock-based compensation expense, Total	$ 19,517	$ 36,578	$ 40,867	$ 65,237