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Commitments and Contingencies (Details)
12 Months Ended
Dec. 31, 2017
USD ($)
Complaint
Dec. 31, 2016
USD ($)
Dec. 31, 2015
USD ($)
Operating Leases [Abstract]      
2018 [1] $ 373,000    
2019 [1] 278,000    
2020 [1] 59,000    
2021 [1] 0    
2022 [1] 0    
Thereafter [1] 0    
Total [1] 710,000    
Employment Agreements [Abstract]      
2018 [2] 1,678,000    
2019 [2] 1,057,000    
2020 [2] 1,057,000    
2021 [2] 1,057,000    
2022 [2] 0    
Thereafter [2] 0    
Total [2] 4,849,000    
Research and Development [Abstract]      
2018 [3] 1,000,000    
2019 [3] 0    
2020 [3] 0    
2021 [3] 0    
2022 [3] 0    
Thereafter [3] 0    
Total [3] 1,000,000    
Total [Abstract]      
2018 3,051,000    
2019 1,335,000    
2020 1,116,000    
2021 1,057,000    
2022 0    
Thereafter 0    
Total 6,559,000    
Lease expense 420,106 $ 358,247 $ 351,075
Loss Contingencies [Line Items]      
Potential future payments 7,500,000    
Issuance of common stock $ 28,037 $ 18,553  
Number of competing derivative complaints | Complaint 2    
Litigation setttlements $ 6,500,000    
Aldoxorubicin [Member]      
Loss Contingencies [Line Items]      
Issuance of common stock $ 18,300,000    
[1] Operating leases are primarily facility lease related obligations, as well as equipment lease obligations with third party vendors. The Company recognized rent expenses of $420,106, $358,247, and $351,075 in 2017, 2016 and 2015, respectively.
[2] Employment agreements include management contracts which have been revised from time to time. The employment agreement for the Company's executive officers provide for minimum salaries, which are adjusted annually at the discretion of the Company's Compensation Committee, and in some cases provide for minimum annual bonuses and employee benefits, as well. New employment agreements for the Company's other executive officers are usually entered into annually or biennially.
[3] Research and development obligations relate primarily to the Reimbursement Agreement with NantCell. All of these purchase obligations are cancelable.