Accrued Expenses and Other Current Liabilities (Details) - USD ($)	Dec. 31, 2017	Dec. 31, 2016
Accounts Payable and Accrued Liabilities, Current [Abstract]
Professional fees	$ 209,000	$ 193,000
Research and development costs	223,000	2,208,000
Litigation settlement	6,450,000	700,000
Wages, bonuses and employee benefits	396,000	487,000
Royalties	626,000	0
Other	125,000	242,000
Total	$ 8,029,274	$ 3,830,498