STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($)	Preferred Stock [Member] Series B Preferred Stock [Member]	Common Stock [Member]	Additional Paid-in Capital [Member]	Accumulated Deficit [Member]	Treasury Stock [Member]	Total
Balance at Dec. 31, 2013	$ 0	$ 42,118	$ 289,426,100	$ (276,389,604)	$ (2,417,247)	$ 10,661,367
Balance (in shares) at Dec. 31, 2013	0	42,116,964
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of stock options/warrants for compensation and services	$ 0	$ 0	5,139,348	0	0	5,139,348
Issuance of stock options/warrants for compensation and services (in shares)	0	0
Common stock issued in connection with a public offering	$ 0	$ 13,225	80,522,176	0	0	80,535,401
Common stock issued in connection with a public offering (in shares)	0	13,225,000
Issuance of restricted stock for compensation	$ 0	$ 100	626,900	0	0	627,000
Issuance of restricted stock for compensation (in shares)	0	100,000
Issuance of common stock for compensation	$ 0	$ 200	829,800	0	0	830,000
Issuance of common stock for compensation (in shares)	0	200,000
Options and warrants exercised	$ 0	$ 281	431,660	0	0	431,941
Options and warrants exercised (in shares)	0	280,022
Repurchase of common stock for treasury	$ 0	$ 0	0	0	(195,614)	(195,614)
Net loss	0	0	0	(30,117,980)	0	(30,117,980)
Balance at Dec. 31, 2014	$ 0	$ 55,924	376,975,984	(306,507,584)	(2,612,861)	67,911,463
Balance (in shares) at Dec. 31, 2014	0	55,921,986
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of stock options/warrants for compensation and services	$ 0	$ 0	7,384,656	0	0	7,384,656
Issuance of stock options/warrants for compensation and services (in shares)	0	0
Common stock issued in connection with a public offering	$ 0	$ 10,465	26,769,603	0	0	26,780,068
Common stock issued in connection with a public offering (in shares)	0	10,465,000
Options and warrants exercised	$ 0	$ 290	589,711	0	0	590,001
Options and warrants exercised (in shares)	0	292,354
Retirement of treasury stock	$ 0	$ (199)	(2,612,662)	0	2,612,861	0
Retirement of treasury stock (in shares)	0	(199,275)
Net loss	$ 0	$ 0	0	(58,587,190)	0	(58,587,190)
Balance at Dec. 31, 2015	$ 0	$ 66,480	409,107,292	(365,094,774)	0	$ 44,078,998
Balance (in shares) at Dec. 31, 2015	0	66,480,065				66,480,065
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of stock options/warrants for compensation and services	$ 0	$ 0	6,735,576	0	0	$ 6,735,576
Issuance of stock options/warrants for compensation and services (in shares)	0	0
Warrants issued in connection with a public offering	$ 0	$ 0	(6,923,551)	0	0	(6,923,551)
Common stock issued in connection with a public offering	$ 3,300,000	$ 40,112	22,437,145	0	0	25,777,257
Common stock issued in connection with a public offering (in shares)	3,300	40,112,170
Preferred stock conversion	$ (192,000)	$ 457	191,543	0	0	0
Preferred stock conversion (in shares)	(192)	457,143
Issuance of restricted stock grant	$ 0	$ 2,325	0	0	0	2,325
Issuance of restricted stock grant (in shares)	0	2,325,581
Warrants issued in connection with term loan	$ 0	$ 0	633,749	0	0	633,749
Beneficial conversion feature - Series B preferred stock	(314,286)	0	314,286	0	0	0
Series B preferred stock deemed dividend	314,286	0	(314,286)	0	0	0
Options and warrants exercised	0	$ 386	743,765	0	0	$ 744,151
Options and warrants exercised (in shares)		386,358				(56,358)
Class action settlement share issuance	0	$ 1,561	4,498,439	0	0	$ 4,500,000
Class action settlement share issuance (in shares)		1,561,578
Net loss	0	$ 0	0	(50,771,221)	0	(50,771,221)
Balance at Dec. 31, 2016	$ 3,108,000	$ 111,321	$ 437,423,958	$ 415,865,995	$ 0	$ 24,777,284
Balance (in shares) at Dec. 31, 2016	3,108	111,322,895				111,322,895