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Nature of Business (Details)
12 Months Ended
Dec. 31, 2016
USD ($)
Patient
ClinicalSite
Country
Dec. 31, 2015
USD ($)
Dec. 31, 2014
USD ($)
Dec. 31, 2013
USD ($)
Nature of Business [Abstract]        
Number of years Orphan Drug Designation provides several benefits of market exclusivity after approval 7 years      
Number of years soft tissue sarcomas confers market among other benefits 10 years      
Number of patients enrolled | Patient 433      
Number of clinical sites | ClinicalSite 79      
Number of countries | Country 15      
Number of patients found to be statistically significant improvement in progression-free survival | Patient 246      
Hazard ratio 0.62      
Percentage of reduction in the risk of tumor progression 38.00%      
Percentage of patients accounted to enrolled in the trial 57.00%      
Number of patients treated | Patient 312      
Percentage of total trial population 72.00%      
Estimated Projected Expenditure Type [Line Items]        
Number of years projected cash burn required to maintain 3 years      
Projected cash burn $ 10,000,000      
Cash and cash equivalents 56,959,485 $ 22,261,372 $ 32,218,905 $ 11,483,112
Projected expenditures for clinical programs 39,800,000      
Aldoxorubicin [Member]        
Estimated Projected Expenditure Type [Line Items]        
Projected expenditures for clinical programs 16,400,000      
Albumin-Binding Cancer Drugs [Member]        
Estimated Projected Expenditure Type [Line Items]        
Projected expenditures for clinical programs 3,700,000      
General Operation [Member]        
Estimated Projected Expenditure Type [Line Items]        
Projected expenditures for clinical programs 3,200,000      
Other General and Administrative Expenses [Member]        
Estimated Projected Expenditure Type [Line Items]        
Projected expenditures for clinical programs 8,000,000      
Interest and Principal Payments [Member]        
Estimated Projected Expenditure Type [Line Items]        
Projected expenditures for clinical programs $ 8,500,000