Description of Company and Basis of Presentation (Details)	3 Months Ended		9 Months Ended
	Sep. 30, 2016 Patient	Mar. 31, 2016 Event	Sep. 30, 2016 ClinicalSite Country
Description of Company and Basis of Presentation [Abstract]
Number of patients enrolled | Patient	433
Number of clinical sites | ClinicalSite			79
Number of countries | Country			15
Number of progression events | Event		191