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CONDENSED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($)
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Cash flows from operating activities:    
Net loss $ (12,643,112) $ (17,524,550)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 102,434 88,490
Stock-based compensation expense 1,325,817 1,384,893
Fair value adjustment on warrant liability 184,272 1,871,294
Amortization of loan cost and discount 67,150 0
Net foreign exchange gain 0 (47)
Loss on retirement of fixed assets 387 0
Non-cash litigation settlement due in common stock 700,000 0
Changes in assets and liabilities:    
Receivables 3,592,636 (3,133,834)
Interest receivable 28,130 28,373
Prepaid expenses and other current assets (861,255) 2,323,729
Accounts payable (2,172,100) (2,025,513)
Accrued expenses and other current liabilities (3,415,368) 4,360,417
Net cash used in operating activities (13,091,009) (12,626,748)
Cash flows from investing activities:    
Purchase of short-term investments 0 (15,000,000)
Proceeds from the sale of short-term investments 35,035,420 23,520,087
Purchases of equipment and furnishings (238,107) (59,701)
Net cash provided by investing activities 34,797,313 8,460,386
Cash flows from financing activities:    
Proceeds from term loan, net of costs 24,012,078 0
Net proceeds from exercise of stock options 183,000 0
Net cash provided by financing activities 24,195,078 0
Net increase (decrease) in cash and cash equivalents 45,901,382 (4,166,362)
Cash and cash equivalents at beginning of period 22,261,372 32,218,905
Cash and cash equivalents at end of period 68,162,754 28,052,543
Supplemental disclosure of cash flow information:    
Cash paid during the period for interest 145,139 0
Cash paid for income taxes 0 800
Supplemental disclosure of non-cash investing activities:    
Warrants issued in connection with term loan 633,749 0
Equipment and furnishings purchased on credit $ 73,474 $ 7,221