Commitments and contingencies (Details) (USD $) In Millions, unless otherwise specified	6 Months Ended
Jun. 30, 2014 Firm
Commitments and contingencies [Abstract]
Potential future payments	$ 7.5
Number of clinical milestones	2
Payments made on achievement of clinical milestones	2.0
Potential future milestone payments on each additional final marketing approval	1.0
Fishman v. Kriegsman [Member]
Loss Contingencies [Line Items]
Number of external investor and public relations firms unaffiliated with company	2
Silverberg v. Kriegsman [Member]
Loss Contingencies [Line Items]
Number of external investor and public relations firms unaffiliated with company	2
Legal fees	2.5
Legal fees to be reimbursed by insurance carrier	$ 1.6

The number of clinical milestones.

No definition available.

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- Definition

Refers to number of external investor and public relations firms unaffiliated with entity.

+ References

No definition available.

+ Details

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- Definition

The payments made during the period on achievement of clinical milestones.

+ References

No definition available.

+ Details

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- Definition

The potential future milestone payments on each additional final marketing approval as of the balance sheet date.

+ References

No definition available.

+ Details

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- Details

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- Definition

Amount due in settlement of a claim for reimbursement from an insurance company when the Company has suffered a loss covered under an insurance policy. For classified balance sheets, represents the current amount receivable, that is amounts expected to be collected within one year or the normal operating cycle, if longer.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 210

-SubTopic 10

-Section S99

-Paragraph 1

-Subparagraph (SX 210.5-02.8)

-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

+ Details

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- Details

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- Definition

The fair value, as of the date of each statement of financial position presented, of other assets which are owned but transferred to serve as collateral for the payment of the related debt obligation, and that are reclassified and separately reported in the statement of financial position because the transferee has the right by contract or custom to sell or re-pledge them.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 860

-SubTopic 30

-Section 45

-Paragraph 1

-URI http://asc.fasb.org/extlink&oid=6467456&loc=d3e113888-111728

+ Details

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- Definition

A fee charged for services from professionals such as doctors, lawyers and accountants. The term is often expanded to include other professions, for example, pharmacists charging to maintain a medicinal profile of a client or customer.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 946

-SubTopic 225

-Section S99

-Paragraph 1

-Subparagraph (SX 210.6-07.2(a),(b),(c),(d))

-URI http://asc.fasb.org/extlink&oid=6488393&loc=d3e606610-122999

Reference 2: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

-Name Accounting Standards Codification

-Topic 946

-SubTopic 225

-Section 45

-Paragraph 3

-Subparagraph (k)

-URI http://asc.fasb.org/extlink&oid=6488370&loc=d3e13550-115849

+ Details

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