CONSOLIDATED STATEMENTS OF OPERATIONS (USD $)	12 Months Ended
	Dec. 31, 2013	Dec. 31, 2012	Dec. 31, 2011
Revenue:
Licensing revenue	$ 300,000	$ 100,000	$ 250,000
Expenses:
Research and development	17,500,469	12,684,793	15,491,301
General and administrative	10,273,576	8,353,330	7,317,169
Depreciation and amortization	120,399	113,936	95,517
Total Expenses	27,894,444	21,152,059	22,903,987
Loss before other income	(27,594,444)	(21,052,059)	(22,653,987)
Other income (loss):
Interest income	137,676	131,666	207,217
Other income, net	183,025	191,416	205,194
Gain (loss) on warrant liability	(20,210,094)	2,766,704	7,915,027
Loss before provision for income taxes	(47,483,837)	(17,962,273)	(14,326,549)
Income tax expense	(1,600)	(1,600)	(97,996)
Net loss	$ (47,485,437)	$ (17,963,873)	$ (14,424,545)
Basic and diluted loss per share	$ (1.44)	$ (0.78)	$ (0.80)
Basic weighted average shares outstanding (in shares)	32,891,202	22,973,905	17,935,895
Diluted weighted average shares outstanding (in shares)	32,891,202	22,973,905	17,935,895