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CONDENSED STATEMENTS OF CASH FLOWS (Unaudited) (USD $)
3 Months Ended
Mar. 31, 2013
Mar. 31, 2012
Cash flows from operating activities:    
Net loss $ (6,864,109) $ (10,134,879)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 29,539 26,184
Retirement of fixed assets 0 2,187
Stock compensation and warrant expense 308,008 321,614
Fair value adjustment on warrant liability 2,095,220 3,888,166
Net foreign exchange gain (132,244) 0
Income from receipt of Mast Therapeutics, Inc. shares (62,945) 0
Changes in assets and liabilities:    
Receivable 99,508 172,325
Interest receivable (13,651) 29,720
Prepaid expenses and other current assets (250,057) 211,020
Accounts payable (1,210,009) 534,804
Accrued expenses and other current liabilities 88,767 916,530
Net cash used in operating activities (5,911,973) (4,032,329)
Cash flows from investing activities:    
Proceeds from sale of short-term investments 3,000,000 2,989,902
Purchases of equipment and furnishings (2,444) (29,467)
Net cash provided by investing activities 2,997,556 2,960,435
Net decrease in cash and cash equivalents (2,914,417) (1,071,894)
Cash and cash equivalents at beginning of period 14,344,088 17,988,590
Cash and cash equivalents at end of period 11,429,671 16,916,696
Supplemental disclosure of cash flow information:    
Fixed assets purchased on credit 793 0
Cash paid for income taxes $ 1,600 $ 0