Commitments and Contingencies (Details) (USD $)	12 Months Ended
	Dec. 31, 2012		Dec. 31, 2011	Dec. 31, 2010
Operating leases, future cash payments [Abstract]
2013	$ 332,000	[1]
2014	381,000	[1]
2015	55,000	[1]
Total	768,000	[1]
Lease expense	324,536		321,782	306,513
Employment agreements, future cash payments [Abstract]
2013	2,575,000	[2]
2014	850,000	[2]
2015	850,000	[2]
Total	4,275,000	[2]
Subtotal, future cash payments due [Abstract]
2013	2,907,000
2014	1,231,000
2015	905,000
Total	5,043,000
Research and development, future cash payments due [Abstract]
2013	10,120,000	[3]
2014	2,430,000	[3]
2015	0	[3]
Total	12,550,000	[3]
Total, future minimum payments due [Abstract]
2013	13,027,000
2014	3,661,000
2015	905,000
Total	$ 17,593,000

[1] Operating leases are primarily facility lease related obligations, as well as equipment lease obligations with third party vendors. The Company recognized lease expenses of $324,536, $321,782 and $306,513 in 2012, 2011 and 2010 respectively.

[2] Employment agreements include management contracts which have been revised from time to time. The employment agreement for the Company's President and Chief Executive Officer provides for a minimum salary level, which is adjusted annually at the discretion of the Company's Compensation Committee, as well as for minimum bonuses that are payable. New employment agreements for the Company's other executive officers are entered into annually.

[3] Research and development obligations relate primarily to clinical trials. Most of these purchase obligations are cancelable.