CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We hereby consent to the incorporation by reference in the Prospectuses and Statement of Additional

Information constituting parts of this Post-Effective Amendment No. 55 to the registration statement on

Form N-1A (the “Registration Statement”) of our report dated November 10, 2016, relating to the financial

statements and financial highlights appearing in the September 30, 2016 Annual Report to Shareholders of

Vanguard Growth and Income Fund, and of our report dated November 18, 2016, relating to the financial

statements and financial highlights appearing in the September 30, 2016 Annual Report to Shareholders of

Vanguard Structured Broad Market Fund and Vanguard Structured Large-Cap Equity Fund (comprising

Vanguard Quantitative Funds), which reports are also incorporated by reference into the Registration

Statement. We also consent to the references to us under the heading “Financial Highlights” in the

Prospectuses and under the headings “Financial Statements” and “Service Providers—Independent

Registered Public Accounting Firm” in the Statement of Additional Information.

/s/PricewaterhouseCoopers LLP

Philadelphia, PA

January 24, 2017