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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
 FlIMpcFxGbj+dvO71JsfETxXto/IXrQJqFmPEgrpHIjOqbNnEeZkzL98ichHiqhD
 xIJ78NtoHj0IIApp9OsSnQ==

<SEC-DOCUMENT>0001144204-10-062446.txt : 20101119
<SEC-HEADER>0001144204-10-062446.hdr.sgml : 20101119
<ACCEPTANCE-DATETIME>20101119164055
ACCESSION NUMBER:		0001144204-10-062446
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20101117
FILED AS OF DATE:		20101119
DATE AS OF CHANGE:		20101119

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Song Chun Fang
		CENTRAL INDEX KEY:			0001428710

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-34080
		FILM NUMBER:		101206034

	MAIL ADDRESS:	
		STREET 1:		C/O CHINA SKY ONE MEDICAL, INC
		STREET 2:		SONG BEI DISTRICT
		CITY:			HARBIN, HEILONGJIANG PROVINCE
		STATE:			F4
		ZIP:			150028

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CHINA SKY ONE MEDICAL, INC.
		CENTRAL INDEX KEY:			0000798985
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				870430322
		STATE OF INCORPORATION:			NV
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		NO. 38 DINGXIN 3RD STREET
		STREET 2:		NANGANG DISTRICT, HEILONGJIANG PROVINCE
		CITY:			HARBIN
		STATE:			F4
		ZIP:			150001
		BUSINESS PHONE:		213-488-5131

	MAIL ADDRESS:	
		STREET 1:		865 SO. FIGUEROA ST
		STREET 2:		SUITE 3340-C
		CITY:			LOS ANGELES
		STATE:			CA
		ZIP:			90017

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	COMET TECHNOLOGIES INC
		DATE OF NAME CHANGE:	19990510
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>v203431_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2010-11-17</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000798985</issuerCik>
        <issuerName>CHINA SKY ONE MEDICAL, INC.</issuerName>
        <issuerTradingSymbol>CSKI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001428710</rptOwnerCik>
            <rptOwnerName>Song Chun Fang</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O CHINA SKY ONE MEDICAL, INC</rptOwnerStreet1>
            <rptOwnerStreet2>SONG BEI DISTRICT</rptOwnerStreet2>
            <rptOwnerCity>HARBIN, HEILONGJIANG PROVINCE</rptOwnerCity>
            <rptOwnerState>F4</rptOwnerState>
            <rptOwnerZipCode>150028</rptOwnerZipCode>
            <rptOwnerStateDescription>CHINA</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2010-11-17</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>1919</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>7.8512</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <ownerSignature>
        <signatureName>/s/ Song Chun-fang</signatureName>
        <signatureDate>2010-11-19</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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