<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:ns2="http://www.sec.gov/edgar/common">
    <headerData>
        <submissionType>144</submissionType>
        <filerInfo>
            <filer>
                <filerCredentials>
                    <cik>0001619958</cik>
                    <ccc>XXXXXXXX</ccc>
                </filerCredentials>
            </filer>
            <liveTestFlag>LIVE</liveTestFlag>



        </filerInfo>
    </headerData>
    <formData>
        <issuerInfo>
            <issuerCik>0000798528</issuerCik>
            <issuerName>ODYSSEY MARINE EXPLORATION, INC.</issuerName>
            <secFileNumber>001-31895</secFileNumber>
            <issuerAddress>
                <ns2:street1>205 S. HOOVER BLVD., SUITE 210</ns2:street1>
                <ns2:city>Tampa</ns2:city>
                <ns2:stateOrCountry>FL</ns2:stateOrCountry>
                <ns2:zipCode>33609</ns2:zipCode>
            </issuerAddress>
            <issuerContactPhone>8138761776</issuerContactPhone>
            <nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>JOHN D LONGLEY JR.</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
            <relationshipsToIssuer>
                <relationshipToIssuer>Officer</relationshipToIssuer>
            </relationshipsToIssuer>
        </issuerInfo>
        <securitiesInformation>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <brokerOrMarketmakerDetails>
                <name>Morgan Stanley Smith Barney LLC Executive Financial Services</name>
                <address>
                    <ns2:street1>1 New York Plaza</ns2:street1>
                    <ns2:street2>8th Floor</ns2:street2>
                    <ns2:city>New York</ns2:city>
                    <ns2:stateOrCountry>NY</ns2:stateOrCountry>
                    <ns2:zipCode>10004</ns2:zipCode>
                </address>
            </brokerOrMarketmakerDetails>
            <noOfUnitsSold>6500</noOfUnitsSold>
            <aggregateMarketValue>18330.00</aggregateMarketValue>
            <noOfUnitsOutstanding>45190598</noOfUnitsOutstanding>
            <approxSaleDate>10/13/2025</approxSaleDate>
            <securitiesExchangeName>NASDAQ</securitiesExchangeName>
        </securitiesInformation>
        <securitiesToBeSold>
            <securitiesClassTitle>Common</securitiesClassTitle>
            <acquiredDate>10/13/2025</acquiredDate>
            <natureOfAcquisitionTransaction>Exercise of Stock Options</natureOfAcquisitionTransaction>
            <nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
            <isGiftTransaction>N</isGiftTransaction>
            <amountOfSecuritiesAcquired>6500</amountOfSecuritiesAcquired>
            <paymentDate>10/13/2025</paymentDate>
            <natureOfPayment>Cash</natureOfPayment>
        </securitiesToBeSold>
        <nothingToReportFlagOnSecuritiesSoldInPast3Months>Y</nothingToReportFlagOnSecuritiesSoldInPast3Months>
        <remarks>Sales that were executed on October 13, 2025 are being reported on this Form 144 filed on October 14, 2025 given the EDGAR system was not accepting filings on October 13, 2025 in observance of the federal holiday.</remarks>
        <noticeSignature>
            <noticeDate>10/13/2025</noticeDate>
            <planAdoptionDates>
                <planAdoptionDate>05/15/2025</planAdoptionDate>
            </planAdoptionDates>
            <signature>/s/ John D Longley</signature>
        </noticeSignature>
    </formData>
</edgarSubmission>
