<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2021-12-13</periodOfReport>

    <issuer>
        <issuerCik>0001423902</issuerCik>
        <issuerName>Western Midstream Partners, LP</issuerName>
        <issuerTradingSymbol>WES</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0000797468</rptOwnerCik>
            <rptOwnerName>OCCIDENTAL PETROLEUM CORP /DE/</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>5 GREENWAY PLAZA</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 110</rptOwnerStreet2>
            <rptOwnerCity>HOUSTON</rptOwnerCity>
            <rptOwnerState>TX</rptOwnerState>
            <rptOwnerZipCode>77046</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isTenPercentOwner>true</isTenPercentOwner>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0000856716</rptOwnerCik>
            <rptOwnerName>WESTERN GAS RESOURCES INC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>1099 18TH STREET, SUITE 1200</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>DENVER</rptOwnerCity>
            <rptOwnerState>CO</rptOwnerState>
            <rptOwnerZipCode>80202-1955</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isTenPercentOwner>true</isTenPercentOwner>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001601306</rptOwnerCik>
            <rptOwnerName>APC Midstream Holdings, LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>5 GREENWAY PLAZA</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 110</rptOwnerStreet2>
            <rptOwnerCity>HOUSTON</rptOwnerCity>
            <rptOwnerState>TX</rptOwnerState>
            <rptOwnerZipCode>77046</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isTenPercentOwner>true</isTenPercentOwner>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001771584</rptOwnerCik>
            <rptOwnerName>WGR Asset Holding Co LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>5 GREENWAY PLAZA</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 110</rptOwnerStreet2>
            <rptOwnerCity>HOUSTON</rptOwnerCity>
            <rptOwnerState>TX</rptOwnerState>
            <rptOwnerZipCode>77046</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isTenPercentOwner>true</isTenPercentOwner>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001699285</rptOwnerCik>
            <rptOwnerName>Kerr-McGee Worldwide Corp</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>5 GREENWAY PLAZA</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 110</rptOwnerStreet2>
            <rptOwnerCity>HOUSTON</rptOwnerCity>
            <rptOwnerState>TX</rptOwnerState>
            <rptOwnerZipCode>77046</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isOther>true</isOther>
            <otherText>Former 10% Owner</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001824936</rptOwnerCik>
            <rptOwnerName>Anadarko USH1 Corp</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>5 GREENWAY PLAZA</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 110</rptOwnerStreet2>
            <rptOwnerCity>HOUSTON</rptOwnerCity>
            <rptOwnerState>TX</rptOwnerState>
            <rptOwnerZipCode>77046</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isTenPercentOwner>true</isTenPercentOwner>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>COMMON UNITS (LIMITED PARTNER INTERESTS)</value>
            </securityTitle>
            <transactionDate>
                <value>2021-12-13</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>2500000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>20.09</value>
                    <footnoteId id="F1"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>200281578</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnotes</value>
                    <footnoteId id="F2"/>
                    <footnoteId id="F3"/>
                    <footnoteId id="F4"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">On December 7, 2021, Western Midstream Partners, LP (the &quot;Issuer&quot;) entered into unit purchase agreement with WGR Asset Holding Company LLC (&quot;WGRAH&quot;) pursuant to which the Issuer agreed to purchase 2,500,000 common units representing limited partner interests in the Issuer (the &quot;Common Units&quot;) from WGRAH at a price of $20.09 per Common Unit. WGRAH and the Issuer completed the sale of such Common Units on December 13, 2021.</footnote>
        <footnote id="F2">Following the transaction reported herein, Western Gas Resources, Inc. (&quot;WGR&quot;) holds 161,319,520 Common Units, WGRAH holds 24,139,260 Common Units, APC Midstream Holdings, LLC (&quot;APCMH&quot;) holds 457,849 Common Units and Anadarko USH1 Corporation (&quot;Anadarko USH1&quot;) holds 14,364,949 Common Units. WGR also is the sole member of Western Midstream Holdings, LLC, the 2% economic general partner of the Issuer.</footnote>
        <footnote id="F3">OXY USA Inc. (&quot;OXY USA&quot;) is a wholly owned subsidiary of Occidental Petroleum Corporation (&quot;Occidental&quot;). OXY USA owns 100% of the outstanding membership interests of Occidental Permian Manager LLC (&quot;OPM&quot;) and 100% of the common stock of OXY Oil Partners, Inc. (&quot;OOP&quot;). OOP, OPM and OXY USA together own 100% of the membership interests of New OPL, LLC (&quot;OPL&quot;). OPL owns 100% of the outstanding common stock of Baseball Merger Sub 2, Inc. (&quot;BMS&quot;).</footnote>
        <footnote id="F4">Anadarko Petroleum Corporation (&quot;APC&quot;) is a wholly owned subsidiary of BMS. APC owns (i) 100% of Anadarko Holding Company (&quot;AHC&quot;) and (ii) indirectly, 100% of the common stock of WGR and Kerr-McGee Corporation (&quot;KMG&quot;). WGR is the sole member of APCMH, and APCMH is the sole member of WGRAH. KMG and AHC together own 100% of the common stock of Kerr-McGee Worldwide Corporation (&quot;KMWW&quot;), and APC and KMWW together indirectly own 100% of the common stock of Anadarko USH1. Accordingly, OXY USA, OPM, OOP, OPL, BMS, APC, AHC, WGR, Anadarko USH1, KMG, APCMH, WGRAH and KMWW are all direct or indirect wholly owned subsidiaries of Occidental.</footnote>
    </footnotes>

    <remarks>Due to the limitations of the U.S. Securities and Exchange Commission's electronic filing system, each of Occidental, OXY USA, OPM, OOP, OPL, BMS, APC and AHC are concurrently filing a Form 4 to report the transaction disclosed herein.</remarks>

    <ownerSignature>
        <signatureName>/s/ Nicole E. Clark of Western Gas Resources</signatureName>
        <signatureDate>2021-12-15</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Nicole E. Clark of APC Midstream Holdings, LLC</signatureName>
        <signatureDate>2021-12-15</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Nicole E. Clark of WGR Asset Holding Company, LLC</signatureName>
        <signatureDate>2021-12-15</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Nicole E. Clark of Kerr- McGee Worldwide Corporation</signatureName>
        <signatureDate>2021-12-15</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Nicole E. Clark of Anadarko USH1</signatureName>
        <signatureDate>2021-12-15</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Nicole E. Clark of Kerr-McGee Corporation</signatureName>
        <signatureDate>2021-12-15</signatureDate>
    </ownerSignature>
</ownershipDocument>
