X0303 5 2008-12-31 0 0 1 0000793043 IR BIOSCIENCES HOLDINGS INC IRBS 0001251899 WILHELM MICHAEL K 8767 E.VIA DE VENTURA SUITE 190 SCOTTSDALE AZ 85258 1 1 1 0 President and CEO Common Stock 2004-03-06 4 J 0 L 126612 2.4 A 46200 I Spouse Common Stock 2004-03-16 4 J 0 L 45800 0.79 A 46200 I Spouse Common Stock 2005-07-13 4 J 0 L 500 0.31 D 992527 D Common Stock 2005-07-13 4 J 0 L 25000 0.31 D 992527 D Common Stock 2006-04-13 4 J 0 L 20000 0.18 D 992527 D Common Stock 2006-04-13 4 J 0 L 28000 0.18 D 992527 D Common Stock 2006-04-19 4 J 0 L 250000 0.16 D 992527 D Common Stock 2007-08-24 4 J 0 L 10000 0.16 D 992527 D Common Stock 2008-08-08 4 J 0 L 833334 0.3 A 992527 D Common stock 2005-06-21 4 P 0 L 10000 0.005 A 46200 I minor child Common stock 2005-06-21 4 P 0 L 5000 0.005 A 46200 I minor child Common stock 2005-06-21 4 P 0 L 5000 0.005 A 46200 I minor child Common stock 2005-06-21 4 P 0 L 5000 0.005 A 46200 I minor child Common stock 2006-12-15 4 P 0 L 1000 0.17 A 46200 I minor child Warrant to Purchase Common Stock 2 2003-12-10 4 A 0 L 20000 0 A 2003-12-10 2006-10-10 Common Stock 20000 187014 D Warrant to Purchase Common Stock 0.01 2003-12-10 4 A 0 L 10000 0 A 2003-12-10 2006-12-10 Common Stock 10000 187014 D Warrant to Purchase Common Stock 0.01 2003-12-10 4 A 0 L 20000 0 A 2003-12-10 2006-12-10 Common Stock 20000 187014 D Warrant to Purchase Common Stock 2 2004-03-06 4 A 0 L 500 0 A 2003-12-31 2008-12-31 Common Stock 500 2000 I Spouse Warrant to Purchase Common Stock 0.25 2004-03-06 4 A 0 L 10000 0 A 2003-12-31 2008-12-31 Common Stock 10000 2000 I Spouse Warrant to Purchase Common Stock 0.25 2004-03-06 4 A 0 L 10000 0 A 2003-12-31 2008-12-31 Common Stock 10000 2000 I Spouse Warrant to Purchase Common Stock 0.125 2004-03-18 4 A 0 L 224490 0 A 2004-03-18 2009-03-18 Common Stock 224490 187014 D Warrant to Purchase Common Stock 0.25 2004-04-13 4 A 0 L 250000 0 A 2004-04-13 2009-04-13 Common Stock 250000 187014 D Warrant to Purchase Common Stock 0.25 2004-04-13 4 A 0 L 250000 0 A 2004-04-13 2009-04-13 Common Stock 250000 187014 D Warrant to Purchase Common Stock 0.25 2004-05-17 4 A 0 L 75000 0 A 2004-05-17 2009-05-17 Common Stock 75000 187014 D Warrant to Purchase Common Stock 2 2004-07-22 4 A 0 L 5000 0 A 2004-07-22 2009-07-22 Common Stock 5000 187014 D Warrant to Purchase Common Stock 0.05 2004-07-22 4 A 0 L 80000 0 A 2004-07-22 2009-07-22 Common Stock 80000 187014 D Warrant to Purchase Common Stock 0.25 2004-07-30 4 A 0 L 20000 0 A 2004-07-30 2009-07-30 Common Stock 20000 2000 I Spouse Warrant to Purchase Common Stock 2 2004-08-18 4 A 0 L 1550 0 A 2004-08-18 2009-08-18 Common Stock 1550 187014 D Warrant to Purchase Common Stock 0.09 2008-08-18 4 A 0 L 20800 0 A 2008-08-18 2009-08-18 Common Stock 20800 187014 D Warrant to Purchase Common Stock 0.12 2004-10-15 4 A 0 L 5000000 0 A 2004-10-15 2006-09-30 Common Stock 5000000 2000 I See Footnote 6 Warrant to Purchase Common Stock 0.3 2005-05-20 4 A 0 L 80811 0 A 2005-05-20 2010-05-20 Common Stock 80811 187014 D Warrant to Purchase Common Stock 0.25 2006-07-14 4 A 0 L 300000 0 A 2006-07-14 2011-07-14 Common Stock 300000 187014 D Options to Purchase Common Stock 0.44 2005-05-20 4 A 0 L 150000 0 A 2005-06-19 2010-05-20 Common Stock 150000 815000 D Options to Purchase Common Stock 0.33 2005-08-10 4 A 0 L 103030 0 A 2005-09-09 2010-08-10 Common Stock 103030 815000 D Options to Purchase Common Stock 0.231 2006-07-14 4 A 0 L 1896970 0 A 2006-08-13 2011-07-14 Common Stock 1896970 815000 D Options to Purchase Common Stock 0.22 2006-09-13 4 A 0 L 454545 0 A 2006-10-13 2011-09-12 Common Stock 454545 815000 D Options to Purchase Common Stock 0.22 2006-09-13 4 A 0 L 3045455 0 A 2006-10-13 2011-09-12 Common Stock 3045455 815000 D Options to Purchase Common Stock 0.166 2007-08-01 4 A 0 L 2000000 0 A 2007-08-31 2017-07-31 Common Stock 2000000 815000 D Options to Purchase Common Stock 0.195 2007-08-01 4 A 0 L 500000 0 A 2007-08-31 2017-07-31 Common Stock 500000 815000 D Adjusted for 1 for 10 stock split in August 2008. Reported for initial Form 4 reporting purposes only. Warrants have expired Reported for initial Form 4 reporting purposes only. Warrants have been exercised. Reflects indirect ownership as a result of marriage on March 6, 2004. Conversion of fees due for services. Warrants held by Foresight Capital Corp. which Mr. Wilhelm is deemed to beneficially own as principal owner of Foresight Capital Corp. Private transfer Given per terms of loan agreement Per employment agreement dated August 10, 2005, as amended November 7, 2005 Michael Wilhelm 2009-02-18