X0202 4 2007-04-27 0 0000792977 ADVANCED MAGNETICS INC AMAG 0001298146 Pereira Brian JG C/O ADVANCED MAGNETICS, INC. 125 CAMBRIDGEPARK DRIVE, 6TH FLOOR CAMBRIDGE MA 02140 1 1 0 0 President and CEO Common Stock 2007-04-27 4 M 0 5000 A 8157 D Common Stock 2007-05-02 4 M 0 13000 9.10 A 21157 D Common Stock 2007-05-02 4 S 0 13000 65.13 D 8157 D Common Stock 2007-05-04 4 M 0 2000 9.10 A 10157 D Common Stock 2007-05-04 4 S 0 7000 63.11 D 3157 D Restricted Stock Units 2007-04-27 4 M 0 5000 D Common Stock 5000 0 D Employee Stock Options (Right to Buy) 9.10 2007-05-02 4 M 0 13000 0 D 2015-11-16 Common Stock 13000 0 D Employee Stock Options (Right to Buy) 9.10 2007-05-04 4 M 0 2000 0 D 2015-11-16 Common Stock 2000 0 D Price is N/A. The sales reported on this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person. The shares sold on this date were sold in multiple transactions. This price is the weighted average sales price per share of all shares sold on this date; the actual sale prices per share range from $64.85 to $65.40. The shares sold on this date were sold in multiple transactions. This price is the weighted average sales price per share of all shares sold on this date; the actual sale prices per share range from $62.70 to $63.37. These Restricted Stock Units vested on February 7, 2007. Date is N/A. 100,000 of these options vested on the date of grant which was November 16, 2005. The remaining 150,000 options vest in three equal annual installments. The first installment became exercisable November 16, 2006. The final two installments become exercisable November 16, 2007 and November 16, 2008. /s/ Joseph L. Farmer, attorney-in-fact 2007-05-04