X0202 4 2007-04-02 0 0000792977 ADVANCED MAGNETICS INC AMAG 0000903448 GOLDSTEIN JEROME C/O ADVANCED MAGNETICS, INC. 125 CAMBRIDGEPARK DRIVE, 6TH FLOOR CAMBRIDGE MA 02140 1 1 0 0 Exec Chairman & Treasurer Common Stock 2007-04-02 4 S 0 10000 60.332 D 230252 I By trust. Common Stock 2007-04-02 4 S 0 10000 60.332 D 230242 I By trust. The sales reported on this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the reporting person. The shares sold on this date were sold in multiple transactions. This price is the weighted average sales price per share of all shares sold on this date; the actual sale prices per share range from $60.00 to $60.97. The reported securities are held by the Jerome Goldstein Retained Annuity Trust, in which the reporting person and his spouse are trustees and share voting and investment power. The reported securities are held by the Marlene Goldstein Retained Annuity Trust, in which the reporting person and his spouse are trustees and share voting and investment power. /s/ Joseph L. Farmer, attorney-in-fact 2007-04-02