X0202 5 2006-09-30 0 0 0 0000792977 ADVANCED MAGNETICS INC AMAG 0001118928 ROBERTS EDWARD B C/O ADVANCED MAGNETICS, INC. 125 CAMBRIDGEPARK DRIVE, 6TH FLOOR CAMBRIDGE MA 02140 1 0 0 0 Common Stock 2006-01-26 5 J 0 6927 0 D 42207 I By trust. Common Stock 2006-07-03 5 J 0 5092 0 D 42207 I By trust. Transfer of reported securities, for no consideration, from the Nancy H. Roberts 2004 Qualified Annuity Interest Trust, in which reporting person and his spouse are the sole trustees and share voting and investment power (the "2004 Trust"), to the Nancy H. Roberts 2006 Qualified Annuity Interest Trust, in which reporting person and his spouse are the sole trustees and share voting and investment power (the "2006 Trust"). Includes 20,276 shares held by the Edward B. Roberts 2006 Qualified Anuity Interest Trust, in which the reporting person and his spouse are sole trustees and share voting and investment power, 9,912 shares held by the 2004 Trust, 6,927 shares held by the 2006 Trust and 5,092 shares held by the Nancy H. Roberts Trust - 2003, in which reporting person and his spouse are the sole trustees and share voting and investment power (the "2003 Trust"). The reported securities are held by the 2006 Trust. Transfer of reported securities, for no consideration, from the 2004 Trust to the 2003 Trust. The reported securities are held by the 2003 Trust. /s/ Joseph L. Farmer, attorney-in-fact 2006-11-13