X0202 5 2006-09-30 0 0 0 0000792977 ADVANCED MAGNETICS INC AMAG 0000903448 GOLDSTEIN JEROME C/O ADVANCED MAGNETICS, INC. 125 CAMBRIDGEPARK DRIVE, 6TH FLOOR CAMBRIDGE MA 02140 1 1 0 0 Exec. Chairman & Treasurer Common Stock 2006-08-25 5 G 0 100 0 D 59489 D Common Stock 640033 I See Footnote Includes 269,473 shares held in Mr. Goldstein's grantor retained annuity trusts for which Mr. Goldstein's spouse is one of the trustees and another 269,473 shares held in Mr. Goldstein's spouse's grantor retained annuity trusts, for which Mr. Goldstein is one of the trustees and has shared voting and investment power. Includes 101,087 shares held directly by Mr. Goldstein's spouse. Excludes 30,400 shares held by the Kaplan Goldstein Family Foundation, a charitable foundation whose trustees are Jerome Goldstein, Marlene Kaplan Goldstein, and Mr. and Ms. Goldstein's adult children, each of whom share voting and investment power. /s/ Joseph L. Farmer, attorney-in-fact 2006-11-13