X0202 4 2007-09-25 0 0000792977 AMAG PHARMACEUTICALS INC. AMAG 0001389500 BRENNER LOUIS MD C/O AMAG PHARMACEUTICALS, INC. 125 CAMBRIDGEPARK DRIVE, 6TH FLOOR CAMBRIDGE MA 02140 0 1 0 0 Senior Vice President Employee Stock Options (Right to Buy) 54.97 2007-09-25 4 M 0 18000 A 2017-09-25 Common Stock 18000 18000 D Grant of stock option pursuant to the AMAG Pharmaceuticals, Inc. Amended and Restated 2000 Stock Plan. This option is exercisable in four equal annual installments. The first installment will vest on September 25, 2008, the first anniversary of the grant, and the next three installments will vest on September 25, 2009, September 25, 2010, and September 25, 2011. The exercise price is reported in column 2. /s/ Joseph L. Farmer, attorney-in-fact 2007-09-27