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Collaboration, License and Other Strategic Agreements (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Apr. 03, 2017
Feb. 28, 2017
Jul. 31, 2015
Jun. 30, 2013
Sep. 30, 2017
Jun. 30, 2017
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Collaborative Agreements                  
Shares issued in connection with Endoceutics License Agreement             $ 13,500    
Endoceutics, Inc.                  
Collaborative Agreements                  
Payments related to collaborative arrangement $ 50,000                
Number of shares issued under arrangement 600,000                
Shares issued in connection with Endoceutics License Agreement $ 13,500           12,555 $ 0 $ 0
Future contingent payments (up to)             9,300 $ 0 0
Consideration recorded           $ 83,500      
IPR&D expense           5,800      
Endoceutics, Inc. | 180-day lock-up provision                  
Collaborative Agreements                  
Number of shares issued under arrangement 300,000                
Stock issued, lock-up period 180 days                
Endoceutics, Inc. | One-year lock-up provision                  
Collaborative Agreements                  
Number of shares issued under arrangement 300,000                
Stock issued, lock-up period 1 year                
Palatin Technologies, Inc.                  
Collaborative Agreements                  
Payments related to collaborative arrangement   $ 60,000              
Out-of-pocket expenses (up to)   $ 25,000              
Velo Bio, LLC                  
Collaborative Agreements                  
Upfront payment, option agreement                 $ 10,000
Velo Bio, LLC | Option Exercise and Regulatory Milestone Achievement                  
Collaborative Agreements                  
Future contingent payments (up to)     $ 65,000            
Velo Bio, LLC | Annual Sales Milestone Achievements                  
Collaborative Agreements                  
Future contingent payments (up to)     250,000            
Velo Bio, LLC | Annual Sales Milestone Achievements | Minimum                  
Collaborative Agreements                  
Sales milestone targets     100,000            
Velo Bio, LLC | Annual Sales Milestone Achievements | Maximum                  
Collaborative Agreements                  
Sales milestone targets     $ 900,000            
Velo Bio, LLC | Royalty Threshold Achievement                  
Collaborative Agreements                  
Potential milestone payment, triggering event, royalty percentage     0.00%            
Potential milestone payment, increased percentage     50.00%            
Intrarosa | Endoceutics, Inc.                  
Collaborative Agreements                  
Out-of-pocket expenses (up to) $ 20,000                
Intrarosa | Endoceutics, Inc. | Developed technology rights                  
Collaborative Agreements                  
Finite-lived intangible assets           $ 77,700      
Intrarosa | Endoceutics, Inc. | Delivery of Intrarosa Launch Quantities                  
Collaborative Agreements                  
Payments related to collaborative arrangement         $ 10,000        
Future contingent payments (up to)             10,000    
Intrarosa | Endoceutics, Inc. | First Anniversary of Closing                  
Collaborative Agreements                  
Future contingent payments (up to)             10,000    
Intrarosa | Endoceutics, Inc. | Tiered Royalties                  
Collaborative Agreements                  
Potential milestone payment, triggering event, sales $ 150,000           $ 150,000    
Royalty percentage, maximum 20.00%           20.00%    
Net sales threshold, future contingent payments $ 1,000,000           $ 1,000,000    
Period after first commercial sale 10 years           10 years    
Intrarosa | Endoceutics, Inc. | First Sales Milestone Achievement                  
Collaborative Agreements                  
Future contingent payments (up to) $ 15,000           $ 15,000    
Potential milestone payment, triggering event, sales 150,000           150,000    
Intrarosa | Endoceutics, Inc. | Second Sales Milestone Achievement                  
Collaborative Agreements                  
Future contingent payments (up to) 30,000           30,000    
Potential milestone payment, triggering event, sales 300,000           300,000    
Intrarosa | Endoceutics, Inc. | Third Sales Milestone Achievement                  
Collaborative Agreements                  
Future contingent payments (up to) 850,000           850,000    
Potential milestone payment, triggering event, sales $ 500,000           500,000    
Bremelanotide Products | Palatin Technologies, Inc. | Tiered Royalties                  
Collaborative Agreements                  
Period after first commercial sale   10 years              
Bremelanotide Products | Palatin Technologies, Inc. | First Sales Milestone Achievement                  
Collaborative Agreements                  
Future contingent payments (up to)   $ 25,000              
Potential milestone payment, triggering event, sales   250,000              
Bremelanotide Products | Palatin Technologies, Inc. | Regulatory Milestone Achievement                  
Collaborative Agreements                  
Future contingent payments (up to)   80,000         80,000    
Bremelanotide Products | Palatin Technologies, Inc. | Regulatory Milestone Achievement, Acceptance by U.S.Food And Drug Administration of New Drug Application                  
Collaborative Agreements                  
Future contingent payments (up to)   20,000         20,000    
Bremelanotide Products | Palatin Technologies, Inc. | Regulatory Milestone Achievement, U.S.Food and Drug Administration Approval                  
Collaborative Agreements                  
Future contingent payments (up to)   60,000         60,000    
Bremelanotide Products | Palatin Technologies, Inc. | Achievement of Certain Annual Sales Milestones Over Course of License Agreement                  
Collaborative Agreements                  
Future contingent payments (up to)   $ 300,000         $ 300,000    
MuGard                  
Collaborative Agreements                  
Cost of acquired entity upfront payment       $ 3,300