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Equity-Based Compensation - Narrative (Details)
$ / shares in Units, $ in Millions
1 Months Ended 12 Months Ended 32 Months Ended
May 31, 2017
shares
Feb. 28, 2017
May 31, 2015
shares
Dec. 31, 2017
USD ($)
plan
$ / shares
shares
Dec. 31, 2016
USD ($)
$ / shares
Dec. 31, 2015
USD ($)
$ / shares
Dec. 31, 2017
USD ($)
shares
Nov. 30, 2014
shares
Equity compensation plans                
Number of equity compensation plans | plan       3        
Options granted in period (USD per share) | $ / shares       $ 9.52 $ 10.63 $ 23.57    
Options vested in period (shares)       699,701        
Value of options exercised in period | $       $ 0.4 $ 1.5 $ 31.2    
Compensation cost not yet recognized | $       $ 34.3     $ 34.3  
Stock Options                
Equity compensation plans                
Compensation expense, period for recognition       2 years 5 months        
Compensation cost not yet recognized | $       $ 17.0     17.0  
RSUs                
Equity compensation plans                
Compensation expense, period for recognition       1 year 8 months 18 days        
RSUs granted (USD per share) | $ / shares       $ 24.18 $ 22.28 $ 52.71    
Value of RSUs vested during period | $       $ 12.3 $ 9.1 $ 3.5    
Compensation cost not yet recognized | $       $ 14.9     14.9  
Performance Restricted Stock Units (RSUs)                
Equity compensation plans                
Compensation expense, period for recognition       2 years 1 month        
Compensation cost not yet recognized | $       $ 2.4     $ 2.4  
2000 Equity Plan                
Equity compensation plans                
Remaining number of shares available for future grants (shares)       0     0  
2007 Equity Plan                
Equity compensation plans                
Additional common stock for issuance (shares) 2,485,000              
2007 Equity Plan | Stock Options                
Equity compensation plans                
Remaining number of shares available for future grants (shares)       2,715,012     2,715,012  
Shares authorized for issuance (shares)       9,494,365     9,494,365  
2007 Equity Plan | Stock Options | Minimum                
Equity compensation plans                
Offering period term (years)       7 years        
2007 Equity Plan | Stock Options | Maximum                
Equity compensation plans                
Offering period term (years)       10 years        
2007 Equity Plan | Performance Restricted Stock Units (RSUs)                
Equity compensation plans                
Remaining number of shares available for future grants (shares)       162,750     162,750  
Award vesting period   3 years            
Compensation expense, period for recognition       3 years        
2013 Lumara Equity Plan | Stock Options                
Equity compensation plans                
Remaining number of shares available for future grants (shares)       21,108     21,108  
Shares authorized for issuance (shares)               200,000
Offering period term (years)       10 years        
2015 ESPP | Stock Options                
Equity compensation plans                
Shares authorized for issuance (shares)     200,000          
Offering period term (years)     6 months          
Annual maximum percentage of employee compensation available for ESPP share purchases (percent)     10.00%          
Purchase price per share as a percentage of fair market value of common stock on the first or last day of the plan period (percent)     85.00%          
Shares issued (shares)             199,904  
Inducement Grants | Stock Options                
Equity compensation plans                
Award vesting period       4 years        
Inducement Grants | RSUs                
Equity compensation plans                
Award vesting period       3 years