Long-Term Debt and Other Arrangements (Tables)

12 Months Ended

Dec. 31, 2013

Long-Term Debt and Other Arrangements [Abstract]

Aggregate future principal and final fee payments of interest bearing obligations

Aggregate future principal and final fee payments of the Company’s total interest bearing obligations - long-term as of December 31, 2013 are as follows (in thousands):

Year Ending December 31,	Total
2014	$	5,917
2015		19,127
2016		20,649
		45,693
Less current portion		(5,917	)
Total	$	39,776

Interest expense and amortization of debt issuance costs

Interest expense and amortization of debt issuance costs and discounts, recorded as other expense in the consolidated statements of comprehensive loss for the year ended December 31, 2013, 2012 and 2011 are shown below (in thousands):

	Year ended December 31,
	2013		2012		2011
Interest expense
Servier loan	$	2,152	$	2,097	$	2,087
GECC term loan		2,064		1,850		-
Novartis note		362		397		341
Other		53		43		34
Total interest expense	$	4,631	$	4,387	$	2,462