Long-Term Debt and Other Arrangements (Tables)

12 Months Ended

Dec. 31, 2012

Long-Term Debt and Other Arrangements [Abstract]

Aggregate future principal and final fee payments of interest bearing obligations

Aggregate future principal and final fee payments of the Company's total interest bearing obligations - long-term as of December 31, 2012 are as follows (in thousands):

Year Ending December 31,	Total
2013		3,472
2014		4,167
2015		20,167
2016		19,823
		47,629
Less current portion		(3,472	)
Total	$	44,157

Interest expense and amortization of debt issuance costs

Interest expense and amortization of debt issuance costs and discounts, recorded as other expense in the consolidated statements of comprehensive loss for the year ended December 31, 2012, 2011 and 2010 are shown below (in thousands):

	Year ended December 31,
	2012		2011		2010
Interest expense
Servier loan	$	2,097	$	2,087	$	-
GECC term loan		1,850		-		-
Novartis note		397		341		354
Other		43		34		31
Total interest expense	$	4,387	$	2,462	$	385