CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (unaudited) (USD $) In Thousands, except Per Share data	3 Months Ended		9 Months Ended
	Sep. 30, 2011	Sep. 30, 2010	Sep. 30, 2011	Sep. 30, 2010
Revenues:
License and collaborative fees	$ 4,859	$ 1,410	$ 16,725	$ 1,749
Contract and other revenue	11,349	5,733	31,477	18,025
Royalties	21	3,754	147	4,267
Total revenues	16,229	10,897	48,349	24,041
Operating expenses:
Research and development	15,851	21,345	51,479	58,278
Selling, general and administrative	7,296	6,197	18,779	16,776
Total operating expenses	23,147	27,542	70,258	75,054
Loss from operations	(6,918)	(16,645)	(21,909)	(51,013)
Other income (expense):
Interest expense	(652)	(104)	(1,818)	(281)
Other income (expense)	1,027	3,117	2,734	313
Net loss before taxes	(6,543)	(13,632)	(20,993)	(50,981)
Provision for income tax expense	0	(1)	(15)	(17)
Net loss	$ (6,543)	$ (13,633)	$ (21,008)	$ (50,998)
Basic and diluted net loss per common share	$ (0.20)	$ (0.69)	$ (0.69)	$ (2.87)
Shares used in computing basic and diluted net loss per common share	32,761	19,802	30,623	17,742