Acquisitions and Related Arrangements - HilleVax Acquisition (Details) $ / shares in Units, $ in Thousands					1 Months Ended		12 Months Ended
	Nov. 01, 2025	Sep. 17, 2025 USD ($) $ / shares shares	Aug. 04, 2025 USD ($) Right $ / shares	Jul. 31, 2025	Dec. 31, 2025 USD ($)	Aug. 31, 2021	Dec. 31, 2025 USD ($)	Dec. 31, 2024 USD ($)	Aug. 31, 2025
Asset Acquisition
Restricted cash					$ 50,802		$ 50,802	$ 4,762
Operating lease liabilities					22,578		22,578	900
Lease payments					29,252		29,252
Contingent value rights liabilities - long-term					10,457		10,457
Other income, net							$ 12,238	$ 6,921
Leased facilities, HilleVax - Swiss Lease with lease expiration of September 30, 2026.
Asset Acquisition
Operating lease liabilities		$ 100
Subleased facilities, HilleVax Sublease
Asset Acquisition
Percentage share of security deposit (as a percent)			100.00%
Sublease expiry term	3 years 2 months
Subleased facilities, HilleVax Sublease | Within twelve months of the closing date
Asset Acquisition
Percentage share of sublease (as a percent)							100.00%
Subleased facilities, HilleVax Sublease | After twelve months of the closing date
Asset Acquisition
Percentage share of sublease (as a percent)							90.00%
Subleased facilities, HilleVax Sublease | Restricted cash held for Boston Lease payments
Asset Acquisition
Restricted cash					40,700		$ 40,700
HilleVax
Asset Acquisition
Asset acquisition, share price (in dollars per share) | $ / shares		$ 1.95	$ 1.95
Number of non-transferable contractual CVR per share | Right			1
Percentage share of net proceeds from disposition within two years of merger (as a percent)			90.00%
Percentage share of unused funds in related expense fund at the end of the two-year period (as a percent)			100.00%
Contingent value right agreement, contingent consideration probable					0		0
Operating lease liabilities		$ 22,400
Contingent value rights liability			$ 5,700
Common stock tendered | shares		50,615,092
Lease security deposit		$ 1,600
Sublease Payment		4,100
Acquired right of use assets, fair value		$ 0
Contingent value rights liabilities - long-term					700		700
Other income, net					700
HilleVax | Restricted Stock Unit Awards
Asset Acquisition
Asset acquisition, share price (in dollars per share) | $ / shares		$ 1.95
Total number of underlying shares | shares		137,592
HilleVax | Leased facilities, HilleVax - Swiss Lease with lease expiration of September 30, 2026.
Asset Acquisition
Operating lease liabilities		$ 100
Sublease expiry term				3 years 2 months
Existence of option to extend						true
Period of lease extension									5 years
Lease payments					$ 100		$ 100
HilleVax | Subleased facilities, HilleVax Sublease
Asset Acquisition
Percentage share of sublease or security (as a percent)			100.00%