License, Collaboration, and Other Arrangements - Takeda Collaboration Agreement (Details) - USD ($) $ in Thousands	12 Months Ended		240 Months Ended
	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2025
Acquisitions, Licensing and Other Arrangements
Revenue from contracts with customers	$ 10,350	$ 6,650
Takeda Pharmaceutical Company Limited | Collaboration and Revenue share agreement
Acquisitions, Licensing and Other Arrangements
Revenue from contracts with customers	4,100	100	$ 7,800
Maximum remaining milestone payments	13,000		13,000
Contract assets	0	0	0
Contract liabilities	0	0	0
Capitalized contract costs	$ 0	$ 0	$ 0