UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D. C. 20549
Form 8-K
Current Report Pursuant to Section 13 or 15(d)of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported):  July 21, 2010
First Financial Holdings, Inc.
(Exact name of registrant as specified in charter)
Delaware	0-17122	57-0866076
State or other jurisdiction of incorporation	Commission File Number	I.R.S. Employer I.D. number
2440 Mall Drive, Charleston, South Carolina  29406
(Address of principal executive offices)
Registrant's telephone number (including area code):  (843) 529-5933
Not applicable
(Former name or former address, if changed since last report)

¨ Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

¨ Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

¨ Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

¨ Pre-commencement communications pursuant to Rule 13e-4c under the Exchange Act (17 CFR 240.13e-4(c))

Section 7 – Regulation FD

Item 7.01 Regulation FD Disclosure

First Financial Holdings, Inc. (the “Company”) (NASDAQ GSM: FFCH), CEO R. Wayne Hall and CFO Blaise B. Bettendorf will present at the Keefe, Bruyette & Woods 11th Annual Community Bank Investor Conference on Wednesday, July 28, 2010.  You may access the live webcast via a link on the Company’s website at www.firstfinancialholdings.com.  The presentation will also be available on the Company’s website from July 27 through October 31, 2010.

Section 9 -- Financial Statements and Exhibits

Item 9.01 Financial Statements and Exhibits

(d) Exhibits

Exhibit (99.1). Press Release of July 21, 2010.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

	FIRST FINANCIAL HOLDINGS, INC
	/s/ Blaise B. Bettendorf
	Blaise B. Bettendorf
	Executive Vice President
	and Chief Financial Officer
Date: July 21, 2010

EXHIBIT INDEX

Exhibit Number	Description
99.1	Press Release of July 21, 2010