X0306 4 2022-02-28 0000078003 PFIZER INC PFE 0001817124 SAHNI PAYAL PFIZER INC.-CORP. SECRETARY 235 EAST 42ND ST. NEW YORK NY 10017 1 Executive Vice President Common Stock 2022-02-28 4 F 0 1049.0000 46.9400 D 18753.0000 D Common Stock 9718.0000 I By Rule 16b-3 Plan Phantom Stock Units 2022-02-28 4 A 0 4295.0000 0.0000 A Common Stock 4295.0000 4295.0000 D The reported transaction constitutes the withholding of shares to satisfy tax obligations upon the vesting of restricted stock units (including dividend equivalents thereon). Each unit represents one phantom share of common stock. The reported transaction constitutes the earn-out of Performance Share Awards (including dividend equivalents thereon) which have been deferred into the Pfizer Inc. Deferred Compensation Plan. The units, held under the Deferred Compensation Plan, are paid in cash following the reporting person's separation from service and may be transferred by the reporting person into an alternative investment account at any time. Susan E. Grant, by power of atty., for Payal Sahni 2022-03-01