X0306 4 2022-02-23 0000078003 PFIZER INC PFE 0001805617 DAMICO JENNIFER B. PFIZER INC.-CORP. SECRETARY 235 EAST 42ND ST. NEW YORK NY 10017 1 SVP & Controller Common Stock 2022-02-23 4 M 0 11748.0000 27.3400 A 21668.0000 D Common Stock 2022-02-23 4 F 0 2339.0000 46.8700 D 19329.0000 D Common Stock 2022-02-23 4 F 0 5815.0000 51.2800 D 13514.0000 D Common Stock 2022-02-24 4 A 0 2893.0000 0.0000 A 16407.0000 D Stock Appreciation Rights 27.3400 2022-02-23 4 M 0 11748.0000 0.0000 D 2022-02-23 2022-02-23 Common Stock 11748.0000 0.0000 D Stock Appreciation Rights 45.9600 2022-02-24 4 A 0 11623.0000 0.0000 A 2027-02-24 2027-02-24 Common Stock 11623.0000 11623.0000 D Stock Appreciation Rights 45.9600 2022-02-24 4 A 0 10222.0000 0.0000 A 2029-02-24 2029-02-24 Common Stock 10222.0000 10222.0000 D The reported transaction constitutes the earn-out of stock appreciation rights (including dividend equivalents thereon). The reported transaction constitutes the withholding of shares to satisfy tax obligations in connection with earn-out of stock appreciation rights. The reported transaction constitutes the withholding of shares to cover payment of exercise price in connection with earn-out of stock appreciation rights (including dividend equivalents thereon). Under the terms of the settlement of the stock appreciation rights the 20-day average of the closing prices of Pfizer common stock ending on the settlement date is used. The reported transaction constitutes the grant of restricted stock units, which are subject to certain vesting requirements. The stock appreciation rights, which are subject to certain vesting requirements, will be settled in shares of Pfizer common stock on the fifth anniversary of the date of grant. The stock appreciation rights, which are subject to certain vesting requirements, will be settled in shares of Pfizer common stock on the seventh anniversary of the date of grant. Susan E. Grant, by power of atty., for Jennifer B. Damico 2022-02-25