Identifiable Intangible Assets, Net and Goodwill - Schedule of Finite-lived and Indefinite-lived Intangible Assets (Detail) - USD ($) $ in Millions		Jun. 29, 2025	Dec. 31, 2024
Finite-Lived Intangible Assets [Line Items]
Finite-lived intangible assets, gross carrying amount		$ 104,551	$ 103,397
Finite-lived intangible assets, accumulated amortization	[1]	(70,522)	(67,549)
Finite-lived intangible assets, net		34,028	35,848
Indefinite-lived Intangible Assets [Line Items]
Indefinite-lived intangible assets		18,674	19,563
Intangible assets, gross carrying amount	[1]	123,224	122,961
Finite-lived intangible assets, accumulated amortization	[1]	(70,522)	(67,549)
Identifiable Intangible Assets, less Accumulated Amortization	[1]	52,702	55,411
IPR&D [Member]
Indefinite-lived Intangible Assets [Line Items]
Indefinite-lived intangible assets	[2]	18,213	18,893
License Agreements and Other [Member]
Indefinite-lived Intangible Assets [Line Items]
Indefinite-lived intangible assets	[3]	461	670
Developed technology rights [Member]
Finite-Lived Intangible Assets [Line Items]
Finite-lived intangible assets, gross carrying amount	[2]	100,537	99,397
Finite-lived intangible assets, accumulated amortization	[2]	(67,907)	(65,044)
Finite-lived intangible assets, net	[2]	32,629	34,353
Indefinite-lived Intangible Assets [Line Items]
Finite-lived intangible assets, accumulated amortization	[2]	(67,907)	(65,044)
Brands [Member]
Finite-Lived Intangible Assets [Line Items]
Finite-lived intangible assets, gross carrying amount		1,274	1,277
Finite-lived intangible assets, accumulated amortization		(1,012)	(992)
Finite-lived intangible assets, net		262	285
Indefinite-lived Intangible Assets [Line Items]
Finite-lived intangible assets, accumulated amortization		(1,012)	(992)
License Agreements and Other [Member]
Finite-Lived Intangible Assets [Line Items]
Finite-lived intangible assets, gross carrying amount		2,740	2,724
Finite-lived intangible assets, accumulated amortization		(1,603)	(1,513)
Finite-lived intangible assets, net		1,137	1,210
Indefinite-lived Intangible Assets [Line Items]
Finite-lived intangible assets, accumulated amortization		$ (1,603)	$ (1,513)

[1] The decrease is primarily due to amortization expense of $2.4 billion.

[2] The changes in the gross carrying amounts primarily reflect the transfer of $590 million from IPR&D to developed technology rights for talazoparib (Talzenna), as well as the impact of foreign exchange.

[3] The decrease in the gross carrying amount reflects an impairment of $210 million (see Note 4).