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Segment, Geographic and Other Revenue Information - Schedule of Significant Biopharma Segment Expenses (Details) - USD ($)
$ in Millions
3 Months Ended
Mar. 30, 2025
Mar. 31, 2024
Segment Reporting Information [Line Items]    
Revenues: $ 13,715 $ 14,879
Cost of sales [1] 2,845 3,379
Selling, informational and administrative expenses [1] 3,031 3,495
Research and development expenses [1] 2,203 2,493
Acquired in-process research and development expenses 9 0
Other (income)/deductions––net 953 680
Income from continuing operations before provision/(benefit) for taxes on income [2] 2,785 3,421
Biopharma [Member]    
Segment Reporting Information [Line Items]    
Revenues: 13,441 14,604
Cost of sales 2,314 2,643
Selling, informational and administrative expenses 2,150 2,334
Research and development expenses 1,941 2,151
Acquired in-process research and development expenses 9 0
Other (income)/deductions––net (78) (148)
Income from continuing operations before provision/(benefit) for taxes on income $ 7,105 $ 7,622
[1] Exclusive of amortization of intangible assets.
[2] Income from continuing operations before provision/(benefit) for taxes on income.