Tax Matters - Reconciliation of Gross Unrecognized Tax Benefits (Details) - USD ($) $ in Millions		12 Months Ended
		Dec. 31, 2022		Dec. 31, 2021		Dec. 31, 2020
Reconciliation of Unrecognized Tax Benefits, Excluding Amounts Pertaining to Examined Tax Returns [Roll Forward]
Balance, beginning		$ (6,068)	[1]	$ (5,595)	[1]	$ (5,381)
Acquisitions		(52)		0		37
Divestitures	[2]	0		0		265
Increases based on tax positions taken during a prior period	[3]	(67)		(111)		(232)
Decreases based on tax positions taken during a prior period	[3],[4]	1,339		103		64
Decreases based on settlements for a prior period	[4],[5]	842		24		15
Increases based on tax positions taken during the current period	[3]	(701)		(550)		(411)
Impact of foreign exchange		90		22		(72)
Other, net	[3],[6]	122		40		120
Balance, ending	[1]	$ (4,494)		$ (6,068)		$ (5,595)

[1] In 2022, included in Income taxes payable ($40 million), Other current assets ($3 million), Noncurrent deferred tax assets and other noncurrent tax assets ($1.2 billion), Noncurrent deferred tax liabilities ($5 million) and Other taxes payable ($3.2 billion). In 2021, included in Income taxes payable ($19 million), Other current assets ($42 million), Noncurrent deferred tax assets and other noncurrent tax assets ($3.0 billion), Noncurrent deferred tax liabilities ($5 million) and Other taxes payable ($3.0 billion).

[2] For 2020, related to the separation of Upjohn. See Note 2B.

[3] Primarily included in Provision/(benefit) for taxes on income.

[4] Primarily related to effectively settling certain issues with the U.S. and foreign tax authorities. See Note 5A.

[5] Primarily related to cash payments and reductions of tax attributes.

[6] Primarily related to decreases as a result of a lapse of applicable statutes of limitations.