Restructuring Charges and Other Costs Associated with Acquisitions and Cost-Reduction/Productivity Initiatives - Costs - Footnotes (Detail) - USD ($) $ in Millions				3 Months Ended		12 Months Ended
		Oct. 05, 2022	Mar. 11, 2022	Dec. 31, 2022	Apr. 03, 2022	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Restructuring Cost and Reserve [Line Items]
Restructuring charge (credit)	[1]					$ 882	$ 741	$ 535
Arena [Member] | Restructuring Charges And Acquisition-Related Costs [Member]
Restructuring Cost and Reserve [Line Items]
Post closing compensation expense			$ 138		$ 138
GBT [Member] | Restructuring Charges And Acquisition-Related Costs [Member]
Restructuring Cost and Reserve [Line Items]
Post closing compensation expense		$ 136		$ 136
Biopharma [Member]
Restructuring Cost and Reserve [Line Items]
Restructuring charge (credit)						$ 354	$ 610	$ 71

[1] Primarily represents cost reduction initiatives. Restructuring charges/(credits) associated with Biopharma: ($354 million charge in 2022, $610 million charge in 2021, and $71 million charge in 2020).