Restructuring Charges and Other Costs Associated with Acquisitions and Cost-Reduction/Productivity Initiatives - Narrative (Detail) - Focused Company Plan [Member] $ in Millions	Dec. 31, 2022 USD ($)
Restructuring Cost and Reserve [Line Items]
Restructuring costs incurred to date	$ 3,500
Restructuring costs incurred, percent of total expected costs	85.00%
Biopharma [Member]
Restructuring Cost and Reserve [Line Items]
Restructuring costs incurred to date	$ 1,400
Restructuring charges incurred to date	1,000
End-To-End Research And Development Operations Improvements [Member]
Restructuring Cost and Reserve [Line Items]
Expected cost	$ 500