Restructuring Charges and Other Costs Associated with Acquisitions and Cost-Reduction/Productivity Initiatives - Narrative (Details) - Focused Company Plan [Member] - USD ($) $ in Millions	3 Months Ended	12 Months Ended
	Apr. 03, 2022	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Restructuring Cost and Reserve [Line Items]
Restructuring cost incurred to date	$ 2,300
Biopharma [Member]
Restructuring Cost and Reserve [Line Items]
Restructuring cost incurred to date	875
Restructuring costs incurred	20	$ 712	$ 79	$ 64
Corporate Enabling Functions [Member]
Restructuring Cost and Reserve [Line Items]
Expected restructuring cost	1,800
Go-to Market Model [Member]
Restructuring Cost and Reserve [Line Items]
Expected restructuring cost	1,100
Manufacturing Optimization [Member]
Restructuring Cost and Reserve [Line Items]
Expected restructuring cost	$ 800
Percentage of expected costs to be non-cash	25.00%