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Acquisitions, Divestitures, Equity-Method Investments and Assets and Liabilities Held for Sale, Licensing Arrangements and Research and Development and Collaborative Arrangements - Divestitures (Details) - USD ($)
$ / shares in Units, shares in Millions
1 Months Ended 3 Months Ended 12 Months Ended
Oct. 31, 2018
Sep. 30, 2018
Apr. 30, 2018
Dec. 31, 2018
Jul. 01, 2018
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2014
Feb. 03, 2017
Oct. 06, 2016
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]                      
Gain representing difference between fair value of equity investment and book value of assets transferred           $ 454,000,000 $ 586,000,000 $ 224,000,000      
Equity securities with readily determinable fair values(a)       $ 1,600,000,000   705,000,000 1,600,000,000        
Disposal Group, Held-for-sale, Not Discontinued Operations [Member]                      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]                      
Assets held for sale       9,725,000,000     9,725,000,000        
Disposed of by Sale, Not Discontinued Operations [Member] | Phase 2b Ready AMPA Receptor Potentiator For CIAS [Member]                      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]                      
Cash and common stock to be received for disposition     $ 75,000,000 85,000,000     85,000,000        
Maximum amount of milestone payments to be received     $ 515,000,000                
ICU Medical [Member] | Disposal Group, Held-for-sale, Not Discontinued Operations [Member] | HIS [Member]                      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]                      
Cash and common stock to be received for disposition                     $ 1,000,000,000
ICU Medical [Member] | Disposed of by Sale, Not Discontinued Operations [Member] | HIS [Member]                      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]                      
Cash and common stock to be received for disposition                   $ 900,000,000  
Shares of common stock received for disposal                   3.2  
Value of common stock received for disposal                   $ 428,000,000  
Gain from sale of shares             302,000,000        
Gain representing difference between fair value of equity investment and book value of assets transferred             47,000,000        
Consideration receivable                   75,000,000  
Cash proceeds from disposal               200,000,000      
Maximum contingent consideration                   $ 225,000,000  
Cellectis [Member]                      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]                      
Ownership percentage                 7.00%    
Upfront payment                 $ 80,000,000    
Allogene [Member]                      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]                      
Ownership percentage 18.00%   25.00%                
Gain from contribution agreement         $ 50,000,000   50,000,000        
Cerevel [Member] | Bain Capital [Member]                      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]                      
Gain representing difference between fair value of equity investment and book value of assets transferred   $ 343,000,000         343,000,000        
Cerevel [Member] | Bain Capital [Member] | Disposal Group, Disposed of by Means Other than Sale, Not Discontinued Operations [Member] | Neuroscience Assets [Member]                      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]                      
Committed investment from collaborator           350,000,000          
Assets held for sale           0          
Long-term Investments [Member] | Allogene [Member]                      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]                      
Equity securities with readily determinable fair values(a)         127,000,000            
Allogene [Member]                      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]                      
Share price (in dollars per share) $ 25                    
Other Nonoperating Income (Expense) [Member] | Disposed of by Sale, Not Discontinued Operations [Member] | Phase 2b Ready AMPA Receptor Potentiator For CIAS [Member]                      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]                      
Cash and common stock to be received for disposition         $ 75,000,000            
Milestone payment recognized       $ 10,000,000              
Cerevel Therapeutics [Member] | Cerevel [Member]                      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]                      
Ownership percentage   25.00%                  
Segment Reconciling Items [Member]                      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]                      
Gain representing difference between fair value of equity investment and book value of assets transferred           $ 415,000,000 586,000,000 224,000,000      
Segment Reconciling Items [Member] | HIS [Member]                      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]                      
Income (loss) on sale of assets             1,000,000 $ (55,000,000)      
Segment Reconciling Items [Member] | Allogene [Member]                      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]                      
Gain from contribution agreement             50,000,000        
Segment Reconciling Items [Member] | Cerevel [Member] | Bain Capital [Member]                      
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]                      
Gain representing difference between fair value of equity investment and book value of assets transferred             $ 343,000,000