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Financial Instruments - Other Noncurrent Liabilities (Detail) - USD ($)
$ in Millions
1 Months Ended 3 Months Ended 9 Months Ended
Apr. 30, 2018
Dec. 31, 2017
Aug. 31, 2017
Jun. 30, 2017
Sep. 30, 2018
Jul. 01, 2018
Sep. 30, 2018
Aug. 31, 2018
Jun. 30, 2018
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net   $ 36,562     $ 36,012   $ 36,012    
Developed Technology Rights [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net [1]   $ 34,765     34,337   34,337    
EU [Member] | Mylotarg [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Term over which fixed annual payments are to be made 10 years                
Aggregate amount of guaranteed fixed annual payments to be made in connection with research and development arrangement $ 301                
EU [Member] | Mylotarg [Member] | Developed Technology Rights [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net $ 240                
Lump sum payment for liability buyout                 $ 224
Non-cash gain from buyout transaction           $ 17 17    
EU [Member] | Besponsa [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Term over which fixed annual payments are to be made       9 years          
Aggregate amount of guaranteed fixed annual payments to be made in connection with research and development arrangement       $ 148          
EU [Member] | Besponsa [Member] | Developed Technology Rights [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net       $ 123 121   121    
EU [Member] | Besponsa [Member] | Developed Technology Rights [Member] | Other Current Liabilities [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net         3   3    
EU [Member] | Besponsa [Member] | Developed Technology Rights [Member] | Other Noncurrent Liabilities [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net         118   118    
U.S. [Member] | Bosulif [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Term over which fixed annual payments are to be made   10 years              
Aggregate amount of guaranteed fixed annual payments to be made in connection with research and development arrangement   $ 416              
U.S. [Member] | Bosulif [Member] | Developed Technology Rights [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net   $ 364     208   208    
Lump sum payment for liability buyout               $ 71  
Non-cash gain from buyout transaction         9        
U.S. [Member] | Bosulif [Member] | Developed Technology Rights [Member] | Other Current Liabilities [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net         23   23    
U.S. [Member] | Bosulif [Member] | Developed Technology Rights [Member] | Other Noncurrent Liabilities [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net         185   185    
U.S. [Member] | Besponsa [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Term over which fixed annual payments are to be made     9 years            
Aggregate amount of guaranteed fixed annual payments to be made in connection with research and development arrangement     $ 296            
U.S. [Member] | Besponsa [Member] | Developed Technology Rights [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net     $ 248   240   240    
U.S. [Member] | Besponsa [Member] | Developed Technology Rights [Member] | Other Current Liabilities [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net         7   7    
U.S. [Member] | Besponsa [Member] | Developed Technology Rights [Member] | Other Noncurrent Liabilities [Member]                  
Finite-Lived Intangible Assets [Line Items]                  
Finite-lived intangible assets, net         $ 233   $ 233    
[1] The changes in the gross carrying amount of Developed technology rights and IPR&D primarily reflect (i) the transfer of $2.7 billion from IPR&D to Developed technology rights to reflect the approval of Xtandi in the U.S. for the treatment of men with non-metastatic castration-resistant prostate cancer, which is being developed through a collaboration with Astellas, and (ii) $240 million of Developed technology rights recorded in connection with the EU approval of Mylotarg (see Note 7E).