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Financial Instruments - Other Noncurrent Liabilities (Detail) - USD ($)
$ in Millions
1 Months Ended
Aug. 31, 2017
Jun. 30, 2017
Oct. 01, 2017
Dec. 31, 2016
Finite-Lived Intangible Assets [Line Items]        
Finite-lived intangible assets, net     $ 37,492 $ 35,664
Developed Technology Rights [Member]        
Finite-Lived Intangible Assets [Line Items]        
Finite-lived intangible assets, net [1]     35,625 $ 33,740
Besponsa [Member] | Developed Technology Rights [Member]        
Finite-Lived Intangible Assets [Line Items]        
Finite-lived intangible assets, net     371  
U.S. [Member] | Besponsa [Member]        
Finite-Lived Intangible Assets [Line Items]        
Term over which fixed annual payments are to be made 9 years      
Aggregate amount of guaranteed fixed annual payments to be made in connection with research and development arrangement $ 296      
U.S. [Member] | Besponsa [Member] | Developed Technology Rights [Member]        
Finite-Lived Intangible Assets [Line Items]        
Finite-lived intangible assets, net     248  
U.S. [Member] | Besponsa [Member] | Developed Technology Rights [Member] | Other Noncurrent Liabilities [Member]        
Finite-Lived Intangible Assets [Line Items]        
Finite-lived intangible assets, net     233  
U.S. [Member] | Besponsa [Member] | Developed Technology Rights [Member] | Other Current Liabilities [Member]        
Finite-Lived Intangible Assets [Line Items]        
Finite-lived intangible assets, net     15  
EU [Member] | Besponsa [Member]        
Finite-Lived Intangible Assets [Line Items]        
Term over which fixed annual payments are to be made   9 years    
Aggregate amount of guaranteed fixed annual payments to be made in connection with research and development arrangement   $ 148    
EU [Member] | Besponsa [Member] | Developed Technology Rights [Member]        
Finite-Lived Intangible Assets [Line Items]        
Finite-lived intangible assets, net     123  
EU [Member] | Besponsa [Member] | Developed Technology Rights [Member] | Other Noncurrent Liabilities [Member]        
Finite-Lived Intangible Assets [Line Items]        
Finite-lived intangible assets, net     117  
EU [Member] | Besponsa [Member] | Developed Technology Rights [Member] | Other Current Liabilities [Member]        
Finite-Lived Intangible Assets [Line Items]        
Finite-lived intangible assets, net     $ 6  
[1] The changes in the gross carrying amount of Developed technology rights and IPR&D primarily reflect (i) the transfer of $4.8 billion from IPR&D to Developed technology rights to reflect the approval of Eucrisa, (ii) the Developed technology rights and IPR&D acquired as part of the acquisition of AstraZeneca’s small molecule anti-infectives business (see Note 2A), (iii) the Developed technology rights of $371 million recorded in connection with the EU and U.S. approvals of Besponsa (see Note 7E), partially offset by (iv) measurement period adjustments related to Medivation (see Note 2A) and (v) impairments of Developed technology rights (see Note 4).