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Property, Plant and Equipment (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Property, Plant and Equipment [Line Items]      
Total property, plant and equipment before accumulated depreciation $ 28,125 $ 27,268  
Less: Accumulated depreciation 14,807 13,502  
Property, plant and equipment [2] 13,318 [1],[3] 13,766 [1],[3] $ 11,762
Land [Member]      
Property, Plant and Equipment [Line Items]      
Total property, plant and equipment before accumulated depreciation 530 588  
Buildings [Member]      
Property, Plant and Equipment [Line Items]      
Total property, plant and equipment before accumulated depreciation 9,810 9,604  
Machinery and equipment [Member]      
Property, Plant and Equipment [Line Items]      
Total property, plant and equipment before accumulated depreciation 11,248 10,933  
Furniture, fixtures and other [Member]      
Property, Plant and Equipment [Line Items]      
Total property, plant and equipment before accumulated depreciation 4,410 4,351  
Construction in progress [Member]      
Property, Plant and Equipment [Line Items]      
Total property, plant and equipment before accumulated depreciation $ 2,127 1,791  
Minimum [Member] | Buildings [Member]      
Property, Plant and Equipment [Line Items]      
Useful lives (years) 33 years    
Minimum [Member] | Machinery and equipment [Member]      
Property, Plant and Equipment [Line Items]      
Useful lives (years) 8 years    
Minimum [Member] | Furniture, fixtures and other [Member]      
Property, Plant and Equipment [Line Items]      
Useful lives (years) 3 years    
Maximum [Member] | Buildings [Member]      
Property, Plant and Equipment [Line Items]      
Useful lives (years) 50 years    
Maximum [Member] | Machinery and equipment [Member]      
Property, Plant and Equipment [Line Items]      
Useful lives (years) 20 years    
Maximum [Member] | Furniture, fixtures and other [Member]      
Property, Plant and Equipment [Line Items]      
Useful lives (years) 12 years 6 months    
Disposal Group, Held-for-sale, Not Discontinued Operations [Member] | HIS [Member]      
Property, Plant and Equipment [Line Items]      
PP&E $ 457 $ 0  
[1] Amounts may not add due to rounding.
[2] Reflects legacy Medivation and legacy Anacor amounts in 2016, commencing on the Medivation acquisition date, September 28, 2016, and Anacor acquisition date, June 24, 2016. Reflects legacy Hospira amounts in 2016 and 2015 commencing on the Hospira acquisition date, September 3, 2015.
[3] The decrease in total property, plant and equipment is primarily due to depreciation, the reclassification of $457 million to Assets held for sale (see Note 2B) and, to a lesser extent, impairments and the impact of foreign exchange, partially offset by capital additions.