Acquisition, Collaborative Arrangements and Equity-Method Investment and Cost-Method Investment - Collaborative Arrangements (Details) - Collaborative Arrangement [Member] - USD ($) $ in Millions		1 Months Ended
	Mar. 27, 2015	Feb. 28, 2015
OPKO Health, Inc. [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Upfront payments and milestone payments		$ 295
Contingent collaborative arrangement payments		$ 275
Deferred Revenue [Member] | Eli Lilly & Company (Lilly) [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Upfront payments received	$ 200