Note 5 - Property, Plant and Equipment - Major Classes of Property, Plant and Equipment (Details) - USD ($)		12 Months Ended
		Dec. 31, 2021	Dec. 31, 2020
Property, plant and equipment, gross		$ 21,702,817	$ 38,071,129
Less: Accumulated depreciation and amortization		(9,441,496)	(9,227,566)
Property, plant and equipment, net		12,261,321	28,843,563
Depreciation and amortization expense (1)	[1]	742,287	1,389,145
Land [Member]
Property, plant and equipment, gross		2,220,000	6,929,000
Building [Member]
Property, plant and equipment, gross		6,634,039	15,917,000
Building Improvements [Member]
Property, plant and equipment, gross		5,842,989	8,141,791
Machinery and Equipment [Member]
Property, plant and equipment, gross		3,289,860	3,340,005
Furniture and Fixtures [Member]
Property, plant and equipment, gross		546,765	613,765
Computer Equipment [Member]
Property, plant and equipment, gross		504,037	493,349
Software Development [Member]
Property, plant and equipment, gross		431,331	435,593
Transportation Equipment [Member]
Property, plant and equipment, gross		114,511	114,511
Lab Equipment [Member]
Property, plant and equipment, gross		1,992,179	1,992,179
Construction in Progress [Member]
Property, plant and equipment, gross		$ 127,106	$ 93,936

[1] (1) Includes amortization expense of $112,310 and $124,550 for the year ending December 31, 2021 and the year ended December31, 2020, respectively. Such amortization expense relates to other capitalized and intangibles assets.