X0306 4 2021-11-16 0 0000763901 POPULAR, INC. BPOP 0001503166 MONZON GILBERTO P.O.BOX 362708 SAN JUAN PR 00924 PUERTO RICO 0 1 0 0 EXECUTIVE VICE PRESIDENT Common Stock Par Value $0.01 per share 2021-11-16 4 S 0 5000 84.20 D 41373.476 D Includes 347.059 shares acquired pursuant to reinvestment of dividends paid by the Corporation. The shares were acquired in transaction exempt from Section 16 of the Securities Exchange Act of 1934 pursuant to Rule 16a-11 thereunder. Includes 2.925 shares acquired under Popular Inc. Puerto Rico Savings and Investment Plan in exempt transactions pursuant to Rule 16 of the Securities Exchange Act. Marie Reyes-Rodriguez, Attorney-in-fact 2021-11-17