10KSB 1 v071653_10ksb.htm Unassociated Document
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, DC 20549
 
FORM 10-KSB
 
 ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
 
For the Fiscal Year Ended December 31, 2006
 
 TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 
 
For the Transition Period From _______to_______             
 
Commission File No. 0-23553
 
IMCOR PHARMACEUTICAL CO.
(Name of small business issuer in its charter)
 
NEVADA
(State or other jurisdiction of incorporation or organization)
 
62-1742885
(I.R.S. Employer Identification No.)
 
4660 La Jolla Drive, Suite 500
San Diego, CA 92122
(Address of principal executive offices) (Zip Code)
 
(858) 546-2955
(Registrant’s telephone number, including area code)
 
Securities registered under Section 12(b) of the Exchange Act:  None
 
Securities registered under Section 12(g) of the Exchange Act:  common stock, par value $.001 per share
 
Check whether the issuer is not required to file reports pursuant to Section 13 or 15(d) of the Exchange Act.
 
Check whether the issuer (1) filed all reports required to be filed by Section 13 or 15(d) of the Exchange Act during the past 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.  Yes   No 
 
Check if there is no disclosure of delinquent filers in response to Item 405 of Regulation S-B contained in this form, and no disclosure will be contained, to the best of registrant’s knowledge, in definitive proxy or information statements incorporated by reference in Part III of this Form 10-KSB or any amendment to this Form 10-KSB.   
Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes            No x
 
The issuer’s revenues for its most recent fiscal year: $1,200,000.
 
The aggregate market value of voting and non-voting common stock held by non-affiliates computed as of April 10, 2007, based upon the last sale price of the common stock reported on the Pink Sheets was approximately $41,724.  For purposes of this calculation only, the registrant has assumed that its directors and executive officers, and any person known to the issuer to hold 10% or more of the outstanding common stock, are affiliates.
 
The number of shares outstanding of each of the registrant’s classes of common stock, as of March 31, 2007 was 6,962,456.


 
 
TABLE OF CONTENTS
 
           
Page
PART I. 
 
 
 
 
 
 1
 
 
ITEM 1
 
DESCRIPTION OF BUSINESS. 
 
1
 
 
ITEM 2  
 
DESCRIPTION OF PROPERTY.
 
15
 
 
ITEM 3  
 
LEGAL PROCEEDINGS. 
 
15
 
 
ITEM 4  
 
SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS. 
 
15
PART II. 
 
 
 
 
 
15
 
 
ITEM 5  
 
MARKET FOR COMMON EQUITY, RELATED STOCKHOLDER MATTERS AND SMALL BUSINESS ISSUER PURCHASES OF EQUITY SECURITIES.
 
15
 
 
ITEM 6  
 
MANAGEMENT’S DISCUSSION AND ANALYSIS OR PLAN OF OPERATION. 
 
17
 
 
ITEM 7 
 
FINANCIAL STATEMENTS.
 
30
 
 
ITEM 8
 
CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING AND FINANCIAL DISCLOSURE. 
 
74
 
 
ITEM 8A 
 
CONTROLS AND PROCEDURES. 
 
74
 
 
ITEM 8B
 
OTHER INFORMATION.
 
75
PART III. 
 
 
 
 
 
75
 
 
ITEM 9  
 
DIRECTORS, EXECUTIVE OFFICERS, PROMOTERS AND CONTROL PERSONS; COMPLIANCE WITH SECTION 16(a) OF THE EXCHANGE ACT.
 
75
 
 
ITEM 10
 
EXECUTIVE COMPENSATION. 
 
78
 
 
ITEM 11  
 
SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT AND RELATED STOCKHOLDER MATTERS. 
 
82
 
 
ITEM 12  
 
CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS. 
 
84
 
 
ITEM 13  
 
EXHIBITS. 
 
85
 
 
ITEM 14  
 
PRINCIPAL ACCOUNTANT FEES AND SERVICES. 
 
91
 

 

PART I.
 
 
ITEM 1. DESCRIPTION OF BUSINESS
 
INTRODUCTION
 
The company was incorporated on December 28, 1994 as a Nevada corporation under the name MT Financial Group, Inc. (“MT Financial”). On May 15, 1997, MT Financial changed its name to Photogen Technologies, Inc. (then subsequently on February 5, 2004 to IMCOR Pharmaceutical Co. to reflect the changed nature of our business to imaging pharmaceuticals). On March 4, 2005, we effected a one-for-twenty reverse split of our common stock and the trading symbol for our common stock changed to “ICRP.” We previously effected a one-for-four reverse split of our common stock in 2002. Unless otherwise indicated, all data (including historical numbers) in this Form 10-KSB reflect the impact of the reverse splits.
 
 We have one FDA approved product, Imagent® (perflexane lipid microspheres), an ultrasound imaging contrast agent that we acquired in June 2003.
 
As discussed below, we are not currently marketing Imagent or further developing our technologies or manufacturing products using those technologies and, instead, we are implementing a restructuring plan and evaluating our alternatives with respect to efforts to maximize value to the company, and our shareholders and creditors. We will continue to consider as alternatives the sale or license of our remaining assets, a merger or other strategic transaction.
 
TECHNOLOGIES AND PRODUCTS: IMAGENT 
 
On June 18, 2003, we acquired related diagnostic imaging assets from Alliance Pharmaceutical Corp. (“Alliance”).  The focus of this acquisition was Imagent, an FDA approved contrast agent for ultrasound imaging. Included in our purchase was the lease of an FDA-approved manufacturing facility, and the acquisition of the marketing, manufacturing and supporting infrastructure with experience in the diagnostic imaging field and an intellectual property portfolio of approximately thirty patents in the area of ultrasound imaging.
 
Imagent is a sterile powder comprising hollow, porous microspheres that contain the internal gases perflexane vapor and nitrogen. It was sold in a complete kit which included all the components necessary to prepare and administer the agent; all of which were conveniently stored at room temperature. When the sterile water is added, the formulation is a dispersion of flexible, surfactant-coated microbubbles in a buffered solution. The microbubbles suspended within this solution are, on average, smaller than a red blood cell and, upon injection, circulate freely within the small blood vessels, through the organs and tissue. During an ultrasound exam, the microbubbles are highly “echogenic” in that they strongly reflect the ultrasound beam and provide enhancement within the area being examined.
 
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 The FDA approved Imagent in May 2002 for marketing in the U.S. for use in patients with sub-optimal echocardiograms. Sub-optimal exams often occur in patients who are obese or have other body characteristics or lung conditions which make it difficult for ultrasound waves to penetrate the chest. As the microbubbles travel within the bloodstream they allow visualization of the blood flow and anatomy within the left ventricle or the main pumping chamber of the heart. By improving the delineation of the endocardial borders of the heart with contrast, the physician is better able to diagnose heart disease during an echocardiography examination.
 
As part of the Imagent acquisition, we also assumed a worldwide development and commercialization agreement for Imagent with Schering Aktiengesellschaft (“Schering AG”) providing us exclusive rights to market the product worldwide until mid-2008, with Schering AG to be paid a royalty based on a percentage of net sales.  At the expiration of the period, we have the right to pay all of any remaining royalty obligations to Schering AG up to $20,000,000 and thus retain all rights to the product on a worldwide basis, or alternatively, to allow Schering AG the opportunity to obtain co-promotion rights along with us. With the ability to enter into worldwide development and commercialization agreements for Imagent, in December 2003, we entered into a product license agreement with Kyosei Pharmaceutical Co., Ltd. (“Kyosei”), a unit of Sakai Chemical Industry Co. Ltd., for the development and marketing of Imagent in Japan for all radiology and cardiology indications.  The company and Kyosei amended and restated this license agreement effective as of November 13, 2006 to provide (among other things) relief from our obligation under the original agreement to manufacture and supply Imagent for Kyosei. We assigned to Kyosei certain patents and a trademark for use in Japan, for which we received $1,200,000 in 2006 for our benefit and another $100,000 which we received from Kyosei but passed directly through to Alliance as their share of the license revenue pursuant to the terms of a “Settlement Agreement” between Alliance and us dated as of September 19, 2005.
 
   In October 2004, we entered into a non-exclusive technology cross-license agreement with Bristol-Myers Squibb Medical Imaging, Inc. covering ultrasound contrast agent patents. Under the agreement, Bristol-Myers Squibb Medical Imaging, Inc. and IMCOR will have the right to further develop and commercialize their respective ultrasound contrast imaging agents without risk of infringing upon the other company’s patent rights and without having to pay further license fees or royalties. We received a total payment of $8,500,000 under the terms of the license agreement and a related stock purchase agreement with Bristol-Myers Squibb Company for our Series A Convertible Preferred Stock, and we will have the right of first negotiation to license select compounds from Bristol-Myers Squibb Medical Imaging, Inc. Elsewhere in this Form 10-KSB, we refer to Bristol-Myers Squibb Medical Imaging, Inc. and Bristol-Myers Squibb Company collectively as “Bristol-Myers Squibb.” In 2005, we also entered into a cross-license agreement with affiliates of GE Healthcare Ltd. to settle patent infringement litigation. This license was valued at $1,200,000 in favor of IMCOR, for which we received $1,000,000 directly. The balance, or $200,000, was paid directly to Alliance. 
 
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In connection with our restructuring plan, we have suspended manufacturing operations and vacated our leased manufacturing facility located in San Diego, California. On May 18, 2005, we notified the FDA of the cessation of our manufacturing operations. Because we no longer manufacture Imagent, operations and sales staff are not necessary. Therefore, we no longer maintain the contract sales and distribution agreements with Cardinal Health, Inc. See “Risk Factor -- We no longer maintain any internal quality control and stability program for Imagent,” below.
 
MARKETS FOR IMAGENT 
 
The market for the current indication of all ultrasound contrast agents is for use in imaging patients with sub-optimal echocardiograms. The potential of this market is anticipated to be approximately 20% of the 18 million echocardiograms performed annually in the U.S. The larger market opportunity will be for indications in the diagnosis of coronary artery disease (“CAD”).
 
 Approximately 14 million Americans have CAD. CAD occurs when the coronary arteries become blocked with plaque and no longer deliver adequate amounts of blood, containing nutrients and oxygen, to the heart. The two most commonly used non-invasive imaging techniques for the detection of CAD are nuclear stress perfusion imaging and stress echocardiography imaging. A nuclear stress perfusion examination involves the injection of radioactive labeled drugs at rest and during stress initiated by physical activity or administration of a drug. The patient is then imaged, most commonly using SPECT (single photon emission computed tomography) cameras to detect disparities between the stress and resting perfusion (blood flow) in major areas of the myocardium. Nuclear imaging assesses blood flow to the heart muscle by the radioactive material attaching to live muscle cells of the heart, providing a difference in enhancement between labeled and non-labeled tissue. The limitations of nuclear cardiology are that it:
 
·  
Uses radioactive drugs,
 
·  
Requires expensive imaging equipment,
 
·  
Is usually performed in a hospital,
 
·  
Requires subjecting the patient to cardiac stress, and
 
·  
Costs about $1,000 per procedure and takes 5-6 hours to perform.
 
There are approximately 8 million nuclear stress exams performed in the U.S. annually.
 
 Stress echocardiography imaging, or stress echo, assesses the ability of the heart to contract and circulate blood by observing motion of the walls of the heart in real time. Patients with CAD typically have inadequate perfusion to certain segments of the heart. The reduced flow, during stress, will cause the walls of the heart to move abnormally particularly when increased demands on the heart require more blood flow. This is detected as wall motion abnormalities during a stress echo. Stress is induced in the patient by exercise or pharmacologic agents. This imaging procedure is performed in 30-45 minutes. There are approximately 3 million stress echo studies performed in the U.S. each year.
 
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 While no ultrasound contrast agent is approved for assessment of perfusion to the heart (also called “myocardial perfusion”), non-clinical and clinical research has been conducted to investigate the ability of agents to evaluate the blood flow to the heart muscle and to assist in the detection of CAD.  
 
RAW MATERIALS SUPPLY
 
We have no existing agreements with any raw material providers. Any party to whom we grant the right to further develop Imagent would have to enter into such agreements for its own benefit.
 
RESTRUCTURING PLAN
 
In April 2005, we adopted an initial restructuring plan which included a reduction-in-force of a majority of the full-time employees and part-time employees or consultants who perform administrative support, manufacturing and related functions. In addition, a limited number of full-time employees were transferred to part-time positions to assist us with the actions necessary to curtail our operations. We also suspended our manufacturing operations.
 
Our board of directors later concluded that, for a variety of factors, including some of which are cited in Notes 1 and 13 of our financial statements, it was not probable that we would obtain additional cash funds to continue operating even on a limited basis in the near term. Therefore, during May 2005, we modified our restructuring plan to include the disposition of furniture, fixtures and equipment, to vacate our premises, and other steps to effect an orderly cessation or suspension of operations other than those necessary to facilitate completion of the restructuring plan.
 
During the fiscal year ended December 31, 2006 we continued to implement the restructuring plan by terminating all of the company’s employees. The company’s operations are now maintained by two contract consultants on an as-needed basis. Our primary activities during this time have included:
 
·  
Negotiating and concluding an amendment and restatement of our license agreement with Kyosei, which relieved us of the obligation to manufacture and supply Imagent for Kyosei in exchange for which we transferred to Kyosei certain patents and a trademark for use in Japan, for which we received $1,200,000 as our share of the license fee compensation;
 
·  
Maintaining our intellectual property and patent estate related to Imagent, including conducting those additional activities necessary to preserve the value of this asset for potential other licensing or related strategic transactions;
 
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·  
Investigating with other parties as to potential transactions that would create additional revenues (license, royalty or other form of revenues) from the licensing or sale of Imagent;
 
·  
Meeting our regulatory, financial and tax reporting obligations; and
 
·  
Negotiating with certain creditors and executing related settlement agreements, wherein those certain creditors have agreed to take fractional payments for their liability claims in exchange for full and final release of the related indebtedness, resulting in gains from debt extinguishment inuring to our benefit.
 
As part of the employee reduction plan, the employment of our CEO and President was terminated effective May 31, 2005. We recorded a reserve for severance (equal to one year’s salary, as required by this individual’s employment contract), amounting to $275,000, as expense during the quarter ending June 30, 2005. This obligation remains unpaid and is accordingly included in accrued expenses at December 31, 2006.
 
Our subsidiary, Sentigen, Ltd., a Bermuda entity, currently has no operations. It is likely to be administratively dissolved by the Bermuda authorities.
 
When Imagent was initially acquired in June 2003 from Alliance, we acquired the underlying technology of the FDA approved product Imagent, and an ongoing operation which held the possibility at the time that we could generate at least two strategic sources of revenue: (a) from direct product sales and (b) from product licensing and/or technology cross-licensing activities. For those reasons, the accounting policy was then established that the value of Imagent (“the Purchased Technology”) should be amortized on a straight-line basis into expense over the estimated useful remaining life of the underlying intellectual property, including the patent estate, which was 12 years from the date of the acquisition.
 
As a result of the second part of the strategic revenue plan, that of obtaining cash-based revenues from product licensing and/or technology cross-licensing activities, we received:
 
·  
 $4,000,000 paid by Kyosei, a unit of the Sakai Group in Japan, in December 2003 and April 2004 pursuant to a product license;
 
·  
$4,000,000 paid by Bristol-Myers Squibb in October 2004 for a technology cross-license;
 
·  
$1,200,000 paid by Amersham Health Inc. (“Amersham”) and affiliates in September 2005 for a technology cross-license; and
 
·  
$1,200,000 paid by Kyosei in November and December 2006 in connection with the amendment and restatement of the original product license agreement referenced above.
 
5

 
We have no material future performance obligations in the furtherance of the two technology cross-license agreements with Bristol-Myers Squibb and Amersham, and the amended and restated license agreement with Kyosei.
 
 The Imagent acquisition transaction and the related follow-on transactions for the above-described strategic revenues collected through 2005, together with the derivative royalties obligation owed to Schering AG (as related to the Kyosei product license agreement and its amendment/restatement) were inextricably related to one another. Accordingly, our accounting policies were adopted with one objective being to match the recognition of license/cross-license revenue and related royalties expense to the underlying amortization of Imagent, especially during the time we were a fully functioning company with both production and selling capabilities. Therefore, up to December 31, 2005, the related license fees and royalties had been deferred and only partially recognized on a straight-line basis into license revenue and royalties expense, based on schedules which commenced on the dates the respective transactions were concluded, and over the remaining estimated useful lives of the underlying technology.
 
Prior to December 31, 2005, we were not able to predict what types of arrangements might ultimately be made with potential business partners for Imagent, financial or otherwise. At December 31, 2005, we made an estimate as to the certainty of additional revenues which might flow from the underlying Imagent asset, license or otherwise, particularly in light of our overall restructuring activities commenced in 2005 and the cessation of normal operations, and concluded that the net fair value of the underlying Imagent Purchased Technology should not exceed $1,000,000. In part this valuation was also made after also taking into consideration one transaction we were then currently negotiating and had a reasonable expectation we might conclude in 2006. Accordingly, we wrote down the carrying value of the Purchased Technology by $11,373,572, as well as the then-remaining deferred revenue credit totaling $8,119,485 and the corresponding remaining deferred royalties asset of $416,666 remaining as of that date, as an impairment charge to operations netting to $3,670,753.
 
 During 2006 we continued to face certain continuing challenges to preserve and optimize the value of Imagent for the benefit of creditors and shareholders, not the least of which is the current lack of a full-time staff and reduced financial resources. Without an immediate capability to manufacture the Imagent product, we were no longer able to support the prospective aspects of the Kyosei product license agreement as originally drafted, therefore we found it necessary to amend and restate the license agreement on mutually acceptable terms. Under the terms of the amended and restated license agreement effective as of November 13, 2006 we were relieved of our obligation to manufacture and supply Imagent for Kyosei and we assigned to Kyosei certain patents and a trademark for use in Japan, for which Kyosei paid a total fees of $1,300,000.
 
In accordance with the terms of the Settlement Agreement between the company and Alliance dated as of September 19, 2005 an aggregate of $100,000 (approximately $91,000 net, after deducting Alliance’s allocated share of direct expenses) of the consideration due from Kyosei was paid to Alliance, and we retained the balance of $1,200,000, which we recorded as license revenues in 2006. After taking into account direct expenditures attributed to this transaction for which the company had remaining responsibility, and which totaled approximately $104,000 (including agent commission fees and incremental royalty obligations to Schering AG), we retained on a net basis approximately $1,096,000.
 
6

 
Following this 2006 transaction with Kyosei, we again assessed the carrying value of the Purchased Technology at December 31, 2006 and decided, in light of the conclusion of this transaction together with the likelihood of concluding any similar transaction in the near term, that we should further reduce the carrying value to $-0-. Therefore, at December 31, 2006, we made a further impairment charge to operations for $1,000,000. We have now established an aggregate impairment allowance of $12,373,572, of which $11,373,572 had previously been established by December 31, 2005, for the Purchased Technology. 
 
In August 2005, we notified the FDA that we suspended any activity related to the Investigational New Drug Application (“IND”). It is unlikely that we can readily restart the production of Imagent without first commencing a lengthy and costly process to reestablish manufacturing capabilities, which also eliminates for the time being the additional possibility of Imagent product sales.
 
As a result our restructuring activities involving the facilities lease termination, sale of equipment, sale of the technology license and impairment of the Purchased Technology, together with the recognition of the related deferred revenues and corresponding deferred royalties, we recorded cumulative asset impairment losses during 2005 and 2006 of $7,506,566 and $1,000,000, respectively (see Note 13 of our financial statements).
 
 We continue to evaluate our alternatives with respect to selling or otherwise maximizing asset values related to our remaining assets, principally consisting of Imagent. We will continue to consider as alternatives the sale or license of our remaining assets, a merger or other material transaction. Such a transaction may include selling Imagent, a license or sale of the patent portfolio underlying Imagent, a manufacturing rights agreement, or another form of transaction. To date, efforts to complete such additional arrangements have not been successful. However, we continue to hold discussions with potentially interested parties, and there remain some potential for a sale, license, development agreement or comparable transaction, however remote, and which may take several months or years to develop and/or consummate.
 
Subject to the availability of capital, we intend to protect our patent portfolio, and seek additional value for the benefit of creditors and shareholders if factors warrant and the underlying cost-benefit analysis supports such action(s). While our history of enforcing our rights in patents indicates that there is merit in this approach, patent protection, enforcement and/or possible litigation activities can be costly, time consuming and the results are inherently uncertain, so there can be no assurance that this business strategy will result in net benefits to us, our creditors or our shareholders.  
 
During the next year, we will focus our limited resources primarily on preserving the value of the Imagent assets, to the extent possible, and exploring various options concerning our business, including joint venturing, licensing or selling the Imagent assets and other possible strategic transactions. We no longer have human, financial and other resources available to us at this time to carry out our original business plan or fully develop and commercialize Imagent on our own. To date our board of directors has only authorized activities in support of the restructuring plan in order to maximize asset value to creditors and shareholders. We must conduct additional investigation before we can reach any definitive conclusions as to the ultimate values of the Imagent assets.
 
7

 
PATENTS 
 
We have twenty issued U.S. patents and four pending U.S. patent applications, which are directed to the composition, manufacture, and use of novel stabilized microbubble compositions used in ultrasound or harmonic ultrasound imaging.  Foreign applications directed to the same subject matter are also granted or pending. We also have five issued U.S. patents covering the use of various contrast agents, including Imagent, in harmonic imaging.
 
 We also attempt to protect our proprietary products, processes and other information by relying on trade secret laws and non-disclosure and confidentiality agreements with our employees, consultants, and certain other persons who have access to such products, processes and information. Among other things, these agreements affirm that all inventions conceived by employees are the exclusive property of the company. “IMCOR” is a trademark and Imagent® is a registered trademark of IMCOR. All other trademarks or trade names used in this registration statement are trademarks or trade names of their respective owners. 
 
GOVERNMENT REGULATIONS 
 
Because we are not currently undertaking any development, manufacturing, or marketing activities, compliance with regulatory matters requires only annual updates of the IND and New Drug Application (“NDA”) to the FDA.
 
All of the products that can be developed from our technologies require approval by the FDA prior to sales being made within the U.S. and by comparable foreign agencies prior to sales being made outside the U.S. Imagent has received FDA approval for use in patients with sub-optimal echocardiograms. The FDA and comparable foreign regulatory agencies impose substantial requirements on the manufacturing and marketing of pharmaceutical products and medical devices. These agencies and other entities extensively regulate, among other things, research and development activities and the testing, manufacturing, quality control, safety, effectiveness, labeling, storage, record keeping, approval, advertising and promotion of these products.
 
 We, like other public companies, are also subject to the requirements of the federal securities laws. Among other things, these laws regulate how we raise capital and how we manage our internal financial and disclosure controls and reporting.
 
 Another area of regulation that could impact the value of Imagent is ongoing developments in health care reimbursement and delivery practices as a means to better control health care costs. Currently, Imagent qualifies for reimbursement in both the in-patient and out-patient cardiac settings by the Centers for Medicare & Medicaid Services. 
 
8

 
 COMPETITION 
 
The industry for contrast agents is intensely competitive, and subject to significant change with respect to technology for the diagnosis and treatment of disease. We expect that competition in the ultrasound contrast imaging agent field (and for our other potential products) will be based primarily on each product’s safety profile, efficacy, stability, ease of administration, breadth of approved indications, and physician, healthcare payor and patient acceptance. There are two ultrasound contrast agents approved in the U.S. for use in cardiology which are competitive with Imagent Optison (sales by GE Healthcare, Inc. have been on hold since 2005 due to sterility problems in manufacturing), and Definity (sold by Bristol-Myers Squibb). POINT Biomedical Corp. filed their New Drug Application (NDA) for Cardiosphere in January 2006. To the best of our knowledge, Acusphere Inc. has completed two Phase III myocardial perfusion studies with Imagify (formerly AI-700). One study for Imagify failed to achieve the endpoint for sensitivity. The second study, completed in October 2006, is undergoing blinded reader re-training to improve the sensitivity values before NDA submission in 2007.
 
Imagent contains no human blood components (albumin), does not require refrigeration, and does not require a mechanical shaker to activate the product. Optison contains human albumin, carrying the appropriate label warnings for injection of a human based product; and it also requires refrigeration. Having this component has limited Optison’s development in certain countries. Definity requires a mechanical shaker to manufacture the microbubble at the patient’s bedside as well as it requires refrigeration. CardioSphere contains human albumin and requires refrigeration. Imagify also requires refrigeration.
 
RISK FACTORS 
 
This Form 10-KSB contains (and other filings with the Securities and Exchange Commission, press releases and other public statements we may issue from time to time may contain) forward-looking statements regarding our business and operations. Statements in this document that are not historical facts are forward-looking statements. Such forward-looking statements include those relating to:
 
·  
Our current business and product development plans,
 
·  
Our future business and product development plans,
 
·  
The timing and results of regulatory approval for proposed products, and
 
·  
Projected capital needs, working capital, liquidity, revenues, costs, and income.
 
Examples of forward-looking statements include predictive statements, statements that depend on or refer to future events or conditions, and statements that may include words such as “expects,” “anticipates,” “intends,” “plans,” “believes,” “estimates,” “should,” “may,” or similar expressions, or statements that imply uncertainty or involve hypothetical events.
 
Forward-looking statements involve known and unknown risks and uncertainties that may cause our actual results in future periods to differ materially from what is currently anticipated. We make cautionary statements in certain sections of this Form 10-KSB, including under “Risk Factors.” You should read these cautionary statements as being applicable to all related forward-looking statements wherever they appear in this Form 10-KSB, in the materials referred to in this Form 10-KSB, in the materials incorporated by reference into this Form 10-KSB, or in our press releases or other public statements. In light of these risks, uncertainties and assumptions, the forward-looking events discussed in this Form 10-KSB or other documents incorporated by reference might not occur. No forward-looking statement is a guarantee of future performance and you should not place undue reliance on any forward-looking statement. We do not undertake any obligation to release publicly any revisions to these forward looking statements, to reflect events or circumstances after the date of this Form 10-KSB, or to reflect the occurrence of unanticipated events, except as may be required under applicable securities laws.
 
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WE CURRENTLY HAVE INSUFFICIENT FUNDS AVAILABLE TO PAY ALL OF OUR LIABILITIES. 
 
Our cash and cash equivalents at December 31, 2006 was approximately $1,309,498. At December 31, 2006, we had current liabilities totaling approximately $4,603,451. 
 
IF WE ARE UNABLE TO FIND A PARTNER OR BUYER OF OUR REMAINING ASSETS AT ACCEPTABLE PRICES WE WILL CONTINUE TO BE UNABLE TO MEET OUR OBLIGATIONS TO OUR CREDITORS AND MAY ENTER INTO BANKRUPTCY PROCEEDINGS, OR LIQUIDATE AND DISSOLVE UNDER APPLICABLE STATE LAWS. 
 
We have implemented a restructuring plan which resulted in a reduction-in-force of all our employees, terminating sales efforts and manufacturing operations, terminating clinical development, vacating our leased premises, selling our furniture, fixtures and manufacturing equipment, and selling our rights to other intellectual property (our iodine-based nanoparticulate contrast agent). Our board of directors has authorized actions necessary to effectuate the restructuring plan.
 
 We plan to focus our efforts primarily on exploring various options concerning our business, including licensing or selling all or a portion of our remaining assets (Imagent), finding a partner with whom to pursue the clinical development and commercialization of Imagent and maintain our patent portfolio. To date, we have not been able to raise sufficient capital to operate the company, and the difficulties and delays in settling the lawsuit with Amersham Health, Inc. have resulted in our vacating our manufacturing facility, stopping the manufacturing of our Imagent product, and terminating clinical development. We need to find an acceptable buyer or partner for our Imagent assets in order to proceed with any type of development plan. If we are not able to find a buyer or partner for these assets in a timely manner and at acceptable prices, we will continue to not have sufficient funds to meet our obligations to our creditors and may be forced into voluntary or involuntary bankruptcy proceedings, or liquidate and dissolve under applicable state laws. The steps to sell or otherwise dispose of our assets (including negotiating agreements and obtaining shareholder approval to the extent required) are costly and will diminish the proceeds available for other purposes. The holder of our Series A Preferred Stock will, under certain circumstances, have a preferred claim on the proceeds of any such transaction. See “Series A Convertible Preferred Stock” below.
 
10

 
WE EXPECT TO INCUR SIGNIFICANT COSTS IN CONNECTION WITH SECURITIES EXCHANGE ACT OF 1934 COMPLIANCE AND MAY ELECT TO REMOVE THE COMPANY FROM THE SECURITIES EXCHANGE ACT OF 1934 REPORTING REQUIREMENTS, WHICH WOULD MAKE RULE 144 RESALES UNAVAILABLE TO INVESTORS. 
 
We are currently subject to the rules of the Exchange Act and the related reporting requirements. Compliance with the reporting requirements of the Exchange Act requires the timely filing of Quarterly Reports on Form 10-QSB, Annual Reports on Form 10-KSB and Current Reports on Form 8-K, among other actions. Our compliance with the reporting requirements involves significant costs and expenditures of management’s time. Given our current financial position and the limited resources of our management, our board of directors may elect to remove the company from the reporting obligations of the Exchange Act at some point in 2007 or thereafter. If we make such an election, investors would not be able to utilize Rule 144 in connection with the resale of their shares of our common stock (until the shares become freely tradable under Rule 144(k)). 
 
OUR CURRENT FINANCIAL SITUATION COULD LEAD TO SHAREHOLDER OR CREDITOR LITIGATION WHICH COULD RESULT IN SUBSTANTIAL COSTS AND DISTRACT OUR MANAGEMENT FROM OUR RESTRUCTURING EFFORTS. 
 
Historically, companies in financial situations similar to ours have often been the target of litigation by creditors or shareholders. We may become involved in this type of litigation as a result of the actions we have taken and/or our inability to meet our obligations to our creditors and others. If such a lawsuit is filed against us, the litigation is likely to be expensive, and, even if we ultimately prevail, the process will divert our attention away from implementing our current restructuring plan. If we do not prevail in such a lawsuit, we may be liable for damages. We cannot predict the amount of such damages, but they may be significant and could further reduce our limited available cash.
 
WE HAVE A HISTORY OF LOSSES, AND WE DO NOT EXPECT TO ACHIEVE OR MAINTAIN PROFITABILITY IN THE FUTURE OR PAY CASH DIVIDENDS. 
 
We have incurred losses since the beginning of our operations. As of December 31, 2006, we have incurred cumulative net losses (before dividends on preferred stock) of approximately $91,239,032. We expect our losses to increase in the future as our financial resources are used to preserve the value of our assets and to the extent possible, pay creditors. It is unlikely that we will be able to achieve or maintain profitability in the future. 
 
We do not anticipate paying any dividends on our common stock in the foreseeable future, and, given our outstanding debt to creditors, it is unlikely that shareholders will receive funds from us if it is dissolved. 
 
WE NO LONGER MAINTAIN A MANUFACTURING FACILITY AND WE MAY ENCOUNTER DIFFICULTIES RESTARTING OUR MANUFACTURING OPERATIONS IF WE CHOSE TO DO SO IN THE FUTURE OR CONTRACTING WITH A CONTRACT MANUFACTURER. 
 
11

 
We have suspended manufacturing operations and vacated our leased manufacturing facility located in San Diego, California. We do not have the resources to resume manufacturing at another facility ourselves and we cannot assume that a third party would be able to take over manufacturing. Any purchaser of Imagent or development or manufacturing partner will be required to comply with FDA manufacturing standards. A new manufacturing facility would require FDA submissions and approvals. Timing of this event, should it occur, would affect initiation of clinical trials and regulatory submissions. All of the above has prevented us from being able to fulfill certain of our previous contractual obligations to provide product (including fulfilling our obligations under our original license agreement with Kyosei). 
 
WE NO LONGER MAINTAIN ANY INTERNAL QUALITY CONTROL AND STABILITY PROGRAM FOR IMAGENT. 
 
Since we have suspended manufacturing operations and vacated our leased manufacturing facility located in San Diego, California, we no longer have the ability to support any clinical testing of the product. 
 
WE NO LONGER MAINTAIN ANY CLINICAL OR REGULATORY STAFF. 
 
We are required to rely on the services of outside consultants for clinical and regulatory advice, and maintenance of the IND and NDA. If we cannot use the services of those consultants, the IND and NDA may have to be abandoned, significantly reducing the assets of the corporation. In August 2005, we notified the FDA that we suspended any activity related to the IND. 
 
FAILURE TO ACHIEVE AND MAINTAIN EFFECTIVE INTERNAL CONTROLS IN ACCORDANCE WITH SECTION 404 OF THE SARBANES-OXLEY ACT COULD HAVE A MATERIAL ADVERSE EFFECT ON OUR BUSINESS AND OPERATING RESULTS. 
 
Effective internal controls are necessary for us to provide reliable financial reports and effectively prevent fraud. If we cannot provide reliable financial reports and prevent fraud, our operating results could be harmed and current and potential stockholders could lose confidence in our financial reporting, which could have a material adverse effect on our stock price and ability to raise capital. Due to the lack of sufficient personnel and financial resources, we have concluded that our internal controls over financial reporting include certain material weaknesses and reportable conditions. For further information concerning our controls, see ”Item 8A. Controls and Procedures.”
 
Beginning in 2004, we began to implement steps to address our internal controls and procedures. We have completed certain steps and had started to implement remediation procedures to address the identified reportable conditions and material weaknesses. However, based on our limited capital resources and the adoption of a restructuring plan in April 2005, which included a reduction-in-force of our full-time employees and part-time employees or consultants who perform financial, administrative support, manufacturing and related functions, we have been unable to complete the previously identified remediation plans. Since it is unlikely that we can further rectify these material weaknesses through measures and improvements to our systems and procedures, management may encounter difficulties in timely assessing business performance and identifying incipient strategic and oversight issues.
 
12

 
 We are committed to maintaining high standards of corporate governance and public disclosure. As a result, our efforts to comply with evolving laws, regulations and standards have resulted in, and are likely to continue to result in, management time and attention being focused on compliance activities. In particular, although the SEC has granted an extension for compliance with certain aspects of Section 404 of the Sarbanes-Oxley Act of 2002 and the related regulations regarding our required assessment of our internal controls over financial reporting and our independent registered public accounting firm’s audit of that assessment, compliance with these regulations will require the commitment of significant financial and managerial resources that we currently do not have. In addition, if we fail to improve our internal controls, we may not be able to conclude on an ongoing basis that we have effective internal controls over financial reporting in accordance with Section 404 of the Sarbanes-Oxley Act. 
 
WE DEPEND ON A SMALL NUMBER OF CONTRACT CONSULTANTS TO PROVIDE MANAGEMENT EXPERTISE, AND THE LOSS OF THIS EXPERTISE MAY INTERFERE WITH OUR OPERATIONS OR DELAY OUR ABILITY TO IMPLEMENT OUR RESTRUCTURING PLAN. 
 
We currently have one acting Principal Executive Officer (Mr. DeFranco) who was a part-time employee of the company until October 2005. Mr. DeFranco became a consultant to the company in November 2005 and is engaged by us on a part-time, as needed basis through June 30, 2007. We also have retained Larry D. Grant, a financial consultant, to provide advisory and management services, on a part-time basis, on financial, operational and strategic matters. These individuals have entered into consulting agreements, confidentiality and/or non-competition agreements with us. If an individual performing one of these executive or consulting functions for us terminates his association with us or breaches their agreement with us: 
 
·  
We would not have anyone available to promote or negotiate a sale or development transaction with a third-party,
 
·  
We could suffer competitive disadvantage or loss of intellectual property protection, and
 
·  
We could experience a delay in our ability to implement our restructuring plan until we arrange for another individual or firm to fulfill the role.
 
13

 
TWO RELATED STOCKHOLDERS HAVE SIGNIFICANT VOTING POWER, WHICH MAY DELAY OR PREVENT A CHANGE OF CONTROL OF IMCOR AND MAY LIMIT THE TRADING VOLUME OF OUR COMMON STOCK. 
 
As of December 31, 2006, two related stockholders controlled approximately 4,652,969 shares, or 66.8% of our issued and outstanding common stock at that date. This concentration of ownership and control may delay or prevent a change in control of IMCOR, and may also result in a small supply of shares available for purchase in the public securities markets. These factors may affect the market and the market price for its common stock in ways that do not reflect the intrinsic value of our common stock.  
 
WE HAVE ISSUED A SUBSTANTIAL NUMBER OF SECURITIES CONVERTIBLE INTO SHARES OF OUR COMMON STOCK THAT WILL RESULT IN SUBSTANTIAL DILUTION TO THE OWNERSHIP INTERESTS OF OUR EXISTING SHAREHOLDERS.
 
As of December 31, 2006, we had reserved 2,437,701 shares of our common stock for issuance upon exercise or conversion of warrants or stock options (including options that have been granted and that are available for grant in the future). Furthermore, on October 29, 2004, we issued and sold 4,500 shares of our newly issued Series A Convertible Preferred Stock which are convertible into 833,334 shares of our common stock.
 
 If our options and warrants are all issued and exercised, or convertible securities converted, investors may experience significant dilution in the voting power of their common stock. The sale of these shares could also place downward pressure on the overall market price of our common stock.
 
APPLICABLE SECURITIES AND EXCHANGE COMMISSION RULES GOVERNING THE TRADING OF “PENNY STOCKS” LIMITS THE TRADING AND LIQUIDITY OF OUR COMMON STOCK, WHICH MAY AFFECT THE TRADING PRICE OF OUR COMMON STOCK. 
 
Our common stock currently is quoted on the Pink Sheets. We are not considering seeking a listing of our shares on another exchange at this time. As a result, our common stock may have fewer market makers, lower trading volumes and larger spreads between bid and asked prices than securities listed on an exchange such as the New York Stock Exchange or the NASDAQ Stock Market. These factors may result in higher price volatility and less market liquidity for our common stock.
 
 Because our common stock is currently trading below $5.00 per share, our common stock is considered a “penny stock” and subject to Securities and Exchange Commission rules and regulations, which impose limitations upon the manner in which our shares can be publicly traded. Our common stock may also trade below $5.00 per share in the future. These regulations require the delivery, prior to any transaction involving a penny stock, of a disclosure schedule explaining the penny stock market and the associated risks. Under these regulations, certain brokers who recommend such securities to persons other than established customers or certain accredited investors must make a special written suitability determination regarding such a purchaser and receive such purchaser’s written agreement to a transaction prior to sale. These regulations have the effect of limiting the trading activity of our common stock and reducing the liquidity of an investment in our common stock. 
 
14

 
 
 
ITEM 3. LEGAL PROCEEDINGS. 
 
 
ITEM 4. SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS. 
 
None. 
 
 
ITEM 5. MARKET FOR COMMON EQUITY, RELATED STOCKHOLDER MATTERS AND SMALL BUSINESS ISSUER PURCHASES OF EQUITY SECURITIES. 
 
COMMON STOCK 
 
Our common stock is quoted from time to time on the Pink Sheets under the symbol “ICRP.PK” As of March 31, 2007, there were approximately 6,962,456 shares of our common stock outstanding and as of March 31, 2007 there were approximately 145 stockholders of record. Holders of our common stock are entitled to receive such dividends as may be declared by our Board of Directors. We have not declared or paid cash dividends on our common stock and we do not anticipate paying any cash dividends in the foreseeable future.
 
 The high and low closing bid prices for our common stock for each quarter of the fiscal years ended December 31, 2005 and December 31, 2006 are set forth below.
 
 
Year Ended
December 31, 2005
(Amounts in $)
 
Year Ended
December 31, 2006
(Amounts in $)
 
 
 
High
 
Low
 
High
 
Low
 
1st Quarter
 
$
2.00
 
$
1.60
 
$
0.10
 
$
0.07
 
2nd Quarter
   
1.65
   
0.06
   
0.10
   
0.026
 
3rd Quarter
   
0.65
   
0.06
   
0.04
   
0.021
 
4th Quarter
   
0.35
   
0.06
   
0.025
   
0.015
 
 
The foregoing information was obtained from the Pink Sheets. The quotations generally reflect inter-dealer prices, without retail mark-up, mark-down or commission and may not represent actual transactions. The foregoing information reflects bid prices, as indicated. See “Risk Factor--Two related stockholders has significant voting power, which may delay or prevent a change of control of IMCOR and may limit the trading volume of our common stock,” above, regarding the possible effects of the concentrated ownership of our stock on the market of our stock.
 
15

 
In 2006, we did not grant any qualified incentive stock options or non-qualified stock options pursuant to our 2000 Long Term Incentive Compensation Plan.
 
All of the shares issued in January through April 2005 were subject to pending registration statements which were not declared effective by the SEC. The effectiveness of the registration statements was delayed while we responded to the SEC’s various comments which arose during the comment process. Given our current financial circumstances and our goal to maximize the funds available to our creditors, our board of directors determined that we would not continue to pursue our efforts to effect our registration statements that were on file with the SEC (File Nos. 333-122625 and 333-117907). Those registration statements have been withdrawn.
 
Many of our investors have held their shares in the Company for more than a year and will be qualified to sell their shares under Rule 144, subject to the restrictions set forth therein; indeed, several such investors have sold shares utilizing Rule 144. For that reason, we stopped accruing penalty shares for certain shareholders who had registration rights. However, given our current financial situation, at some point in 2007 or thereafter we may elect to cease reporting under the Exchange Act, and as a result, investors will no longer be eligible to resell their shares of our common stock under Rule 144 (unless the shares have been held for two years, in which case they would be freely saleable under Rule 144(k)).
 
 As of April 14, 2007, approximately 4,970,248 shares of our common stock are “restricted stock” or are beneficially owned by persons who as of March 31, 2007 were affiliates of the company as defined in Rule 144 under the Securities Act. For purposes of this calculation only (and the comparable disclosure on the cover page of this Form 10-KSB) we have assumed that officers, directors, 10% stockholders and that stock held by Oxford Bioscience Partners IV L.P. and MRNA Fund II L.P., other than shares and warrants which are covered by an effective registration statement, would be deemed to be beneficially owned by Jonathan Fleming (a director) (although Mr. Fleming disclaims beneficial ownership of those shares for all other purposes), and that a person beneficially owns stock subject to an option, warrant or convertible instrument that is exercisable or convertible within 60 days from April 14, 2007. A portion of those shares would be eligible for resale by company affiliates and others who have satisfied the requisite holding periods, subject to the volume limitations and other provisions of Rule 144 and applicable law. As of April 14, 2007, we had approximately 1,992,208 shares eligible for sale free of restriction under Rule 144(k) which are not subject to an effective registration statement. 
 
EQUITY COMPENSATION PLAN INFORMATION 
 
See Part III Item 11 for information regarding our equity compensation plans.
 
16

 
SERIES A CONVERTIBLE PREFERRED STOCK 
 
In October 2004, in connection with our technology cross-licensing agreement, we entered into a securities purchase agreement with Bristol-Myers Squibb pursuant to which we sold an aggregate of 4,500 shares of Series A Convertible Preferred Stock for a total purchase price of $4,500,000. The Certificate of Designation, Preferences and Rights which authorizes the Series A Convertible Preferred Stock generally provides that:
 
·  
In the event of any liquidation, dissolution or winding up of the company (including the sale of all or substantially all the assets of the company unless the holders of 66-2/3% of the preferred stock then outstanding vote not to treat such a sale as a liquidation event), whether voluntary or involuntary, and subject to the rights of the holders of any future senior securities, each holder of preferred stock is entitled to be paid out of the funds and assets of the company available for distribution to holders of our capital stock before any payment or setting apart for payment of any amount shall be made in respect of any common stock, an amount equal to $1,000 per share of preferred stock;
 
·  
The holder of the preferred stock shall have no voting rights except as required by law; and
 
·  
The preferred stock is convertible into common stock at a ratio of 185.1854 shares of common stock for each share of preferred stock. As of December 31, 2006, conversion of the preferred stock would result in issuance of 833,334 shares of our common stock. We have the right to require conversion of the preferred stock into common stock if the closing price of our common stock exceeds $8.10 per share for ten consecutive trading days. The conversion ratio is subject to adjustments for dilution resulting from stock splits and combinations, certain dividends and distributions, reorganization, reclassification or merger of the company.
 
 
Portions of the discussion in this item contain forward-looking statements and are subject to the “Risk Factors” described above. All forward-looking statements included in this item are based on information available to us on the date hereof, and we assume no obligation to update any such forward-looking statements. Our actual results could differ materially from those anticipated in these forward-looking statements as a result of a number of factors, including those set forth in the section captioned “RISK FACTORS” and elsewhere in this Form 10-KSB.
 
 The following should be read in conjunction with our audited financial statements included herein. References to the “Imagent Business” are to the property, plant and equipment, technology and medical imaging business of Alliance that we acquired on June 18, 2003. References to the “Purchased Technology” are to the technology and intellectual property that are part of the Imagent Business.
 
17

 
 These financial statements present the results of operations of the Imagent Business following its acquisition on June 18, 2003 and have been adjusted to reflect the one-for-twenty reverse split effected on March 4, 2005.
 
LIQUIDITY; CAPITAL RESOURCES
 
The independent registered public accounting firm’s report dated April 13, 2007 included in our December 31, 2006 Annual Report on Form 10-KSB, as amended, contained the following explanatory paragraph:
 
The accompanying financial statements have been prepared assuming that the Company will continue as a going concern. As discussed in Note 2 to the financial statements, the Company has reported recurring losses from operations through December 31, 2006 and had a working capital deficit at December 31, 2006. These factors raise substantial doubt about the Company’s ability to continue as a going concern. Management’s plans as to these matters are described in Note 2. The accompanying financial statements do not include any adjustments that might result from the outcome of this uncertainty.
 
 At December 31, 2006, we had cash and cash equivalents totaling approximately $1,309,498, compared to $717,024 at the end of the 2005 fiscal year. At December 31, 2006, we had a net shareholders’ deficit position of $3,263,305, compared to a net shareholders’ deficit position of $2,955,432 at the end of the 2005 fiscal year.
 
 During 2006, our board of directors continued to implement our restructuring plan that resulted in cessation or suspension of substantially all operations, including a complete employee reduction-in-force, sale of excess equipment, suspension of manufacturing and clinical activities, cessation of manufacturing and selling activities, vacating our premises, and the sale and licensing of certain of our technology.
 
 We entered into an amended and restated license agreement with Kyosei effective as of November 13, 2006. Under the terms of the revised agreement we have been relieved of our obligation to manufacture and supply Imagent for Kyosei and we assigned to Kyosei certain patents and a trademark for use in Japan. Kyosei paid a total fee of $1,300,000. In accordance with the terms of our Settlement Agreement with Alliance dated as of September 19, 2005, an aggregate of $100,000 (approximately $91,000 net, after deducting Alliance’s allocated share of direct expenses) of payment from Kyosei was paid to Alliance. In addition, after taking into account direct expenditures attributed to this transaction for which we had remaining responsibility, and which totaled approximately $104,000 (including agent commission fees and incremental royalty obligations to Schering AG), we received net approximately $1,096,000.
 
18

 
From January 1, 2006 through December 31, 2006, significant uses of our cash, which totaled approximately $620,000 (leaving us a net cash amount of $1,309,498 at December 31, 2006) (all amounts approximate) included:
 
·  
$48,000 net commissions to an agent for facilitation of the amended and restated agreement with Kyosei;
 
·  
$132,000 for legal costs associated with patent protection matters related to Imagent, in order to preserve intellectual property viability and values;
 
·  
$81,000 for legal costs associated with general corporate, contract, and SEC reporting matters;
 
·  
$86,000 for accounting and auditing services, including $16,000 related to income tax reporting compliance matters;
 
·  
$36,000 net payments to creditors in exchange for the cancellation of $361,000 in total payable obligations, yielding a gain on extinguishment of debt of $325,000;
 
·  
$96,000 for contract consultants related to all administrative, revenue license negotiations, debt extinguishment negotiations and overall financial and SEC reporting compliance efforts;
 
·  
$75,000 for directors and officers insurance premiums;
 
·  
$19,000 in related SEC compliance expenditures;
 
·  
$15,000 payment to reduce a remaining creditor obligation under the sale of our technology license asset related to our iodine-based nanoparticulate compounds during 2005;
 
·  
$14,000 to a local tax authority as partial payment for unpaid property taxes (an unsecured obligation); and
 
·  
$18,000 other miscellaneous.
 
 From January 1, 2007 through April 5, 2007, significant uses of our cash, which totaled approximately $290,000 (leaving us a net cash amount of $1,035,000 at April 5, 2007) (all amounts approximate) included:
 
·  
$61,000 for legal costs associated with patent protection matters related to Imagent, in order to preserve intellectual property viability and values;
 
·  
$21,000 for legal costs associated with general corporate, contract, and SEC reporting matters;
 
·  
$44,000 for accounting and auditing services, including $13,000 related to income tax reporting compliance matters;
 
19

 
·  
$47,000 net payments to a single creditor in exchange for the cancellation of $417,000 in total payable obligations which were undisputed, and another $100,000 in disputed obligations, yielding a gain on extinguishment of debt of $370,000;
 
·  
$58,000 for directors and officers insurance premiums;
 
·  
$25,000 for contract consultants related to administration, revenue license negotiations, debt extinguishment negotiations and overall financial and SEC reporting compliance efforts;
 
·  
$30,000 transferred to a custodial account related to the remaining royalty payment obligation currently owed to Schering related to the amended and restated license agreement with Kyosei related to our Imagent during the year ending December 31, 2006;
 
·  
$3,000 in related SEC compliance expenditures; and
 
·  
$1,000 other miscellaneous.
 
Based on the lack of potential transactions which might be concluded in the near term, particularly in light of the amended and restated license agreement with Kyosei which we concluded during the year ended December 31 2006, and for which we were paid $1,200,000 as our share of the gross license proceeds, we have determined that the carrying value of the Imagent assets should be written down as of December 31, 2006 to $-0- carrying value by an additional increase in the valuation impairment allowance, with a corresponding charge for the net carrying value of $1,000,000 carried over from December 31, 2005.
 
 We are still considering our alternatives with respect to efforts to sell or otherwise maximize asset values related to the Purchased Technology, and will continue to consider as alternatives the sale or license of our remaining assets, a merger or other material transaction. Such a transaction may include selling the Purchased Technology, a license or sale of the patent portfolio underlying the Purchased Technology, a manufacturing rights agreement, or another form of transaction.
 
We incurred gross decreases to shareholders’ equity totaling approximately $349,816 ($307,873, net of increase in paid-in capital attributed to the recognition of stock option compensation totaling $41,943) during the year ended December 31, 2006. The most significant reduction to shareholders’ equity during this same period resulted from continuing net losses, totaling approximately $349,816. Accordingly, the net shareholders’ deficit of $2,955,432 at December 31, 2005 was increased to a deficit of $3,263,305 at December 31, 2006.
 
Our financial condition raises substantial doubt about our ability to continue as a going concern (which activities have been limited to implementing our restructuring plan as discussed above) without further financing and adjustments to our levels of expenditures that we deem necessary to maximize the remaining asset values. In 2006, our operations consumed approximately $620,236 in cash. However, after giving effect to the gross receipt of $1,200,000 related to the amendment and restatement of the Kyosei agreement and additional cash increases related to $12,711 in interest income, our net cash increased for 2006 by approximately $592,474.
 
20

 
 The “Assumed acquisition obligations” relates primarily to past due payment obligations owed to several parties totaling $622,750 at December 31, 2006. Our former CEO is owed $206,250 for a bonus earned in 2004 and $275,000 for severance relating to the termination of his employment in 2005. No portion of these obligations, totaling $481,250, has been paid; such amounts are included in “Accrued payroll, deferred bonuses and related expenses” at December 31, 2006. For a discussion of other changes in accrued expenses and assumed acquisition obligations see Note 7 to our financial statements.
 
 In connection with our acquisition of the Imagent Business, we undertook certain obligations, including (i) subject to reaching satisfactory agreements with certain Alliance secured and unsecured creditors, to pay an aggregate amount of up to approximately $3,000,000 to creditors, of which all but approximately $1,179,000 has been paid, and (ii) to pay certain royalties based upon sales of Imagent through June 2010, subject to certain offsets. The remaining unpaid obligations assumed in connection with the Imagent Business acquisition referenced above now totals approximately $925,000 at year end 2006.  This includes $622,750 related to certain notes (of which all remain past due at year end). Our other obligations that we assumed from Alliance have been discharged.
 
RESULTS OF OPERATIONS
 
Revenue and License Fees
 
We did not generate significant product revenues during 2005 or 2006, due to capital constraints limiting our sales and marketing capability and the cessation of manufacturing operations related to the closing of our FDA-approved manufacturing facility in 2005. Any sales of products are therefore included in our financial statements under “investment and other income.”
 
 License revenues relate to the amortization and/or recognition of license revenue received but previously deferred in December 2003 ($2,000,000), April 2004 ($2,000,000), October 2004 ($4,000,000), September 2005 ($1,200,000) and November and December 2006 ($1,200,000).
 
In December 2003, we entered into a product license agreement with Kyosei for the development and marketing of Imagent in Japan for all radiology and cardiology indications. We received a gross payment of $2,000,000 from Kyosei in late 2003 and another $2,000,000 in the second quarter of 2004 (both of which were recorded as deferred revenue on a gross basis), less a total of $400,000 of taxes withheld at the source (for which $200,000 was charged against operations in each of 2003 and 2004). In November and December 2006 we entered into an amended and restated license agreement which yielded another $1,300,000, ($1,200,000 to us and $100,000 to Alliance). As a result of these Kyosei payments aggregating $5,300,000, we are obligated to pay Schering AG a total of $530,000 ($100,000 of which was paid in 2004 and an additional amount now totaling $430,000 remains unpaid at December 31, 2006. Through December 31, 2005 we recognized income from these payments ratably over the remaining lives of our related underlying Imagent patents, as calculated at the time the respective payments are received. Subsequent to that date we have recognized the full license fees inuring to our benefit without further deferrals. Accordingly, we recognized $1,200,000 as earned license revenue in 2006, and $338,095 as license revenue in 2005 in connection with the Kyosei agreements. Because we no longer conducted manufacturing operations, effective November 13, 2006 we entered into an amended and restated license agreement with Kyosei which relieved us of the obligation to manufacture and supply Imagent for Kyosei and we assigned to Kyosei certain patents and a trademark for use in Japan. Kyosei paid a total fee of $1,300,000. In accordance with our Settlement Agreement with Alliance dated as of September 19, 2005 an aggregate of $100,000 (approximately $91,000 net, after deducting Alliance’s allocated share of direct expenses) of the Kyosei proceeds was paid to Alliance. After taking into account direct expenditures attributed to this transaction for which we had remaining responsibility, and which totaled approximately $104,000 (including agent commission fees and incremental royalty obligations to Schering AG), we received net approximately $1,096,000.
 
21

 
 In 2004, we entered into a non-exclusive technology cross-license agreement with Bristol-Myers Squibb. We received a gross payment of $4,000,000 in connection with the license and an additional $4,500,000 under a related stock purchase agreement. We have recognized $358,212 and $-0- license revenue for 2005 and 2006, respectively, in connection with this technology license utilizing the same revenue recognition method described above. We do not owe Schering AG any royalty on the payments from this technology license because, among other things, it did not involve our sale of products.
 
 Research and Development 
 
 Essentially all of our research expenses since the third quarter of 2004 until the early second quarter 2005 had been directed toward infrastructure and expenses associated with regulatory compliance and continued development of Imagent for new indications and the maintenance of our manufacturing capability. Since early in the second quarter of 2005, however, the majority of the costs have been expended with a focus on patent considerations, regulatory and clinical considerations in keeping with our overall objective to preserve net asset values for the benefit of creditors and shareholders. In August 2005, we notified the FDA that we suspended any activity related to the IND. Our regulatory and clinical operations were discontinued as part of our restructuring plan.  Based on the discontinuance of our research and development, regulatory and clinical operations, patent costs incurred in connection with preserving the Company’s intellectual property, which previously had been classified as research and development activities, have been reclassified to selling, general and administrative expenses. The following is a summary of our major research and development cost categories (all amounts approximate):

 
 
Fiscal Year Ended
December 31, 2005
 
Fiscal Year Ended
December 31, 2006
 
Increase/
(Decrease)
2005 to 2006
 
Personnel
 
$
746,000
 
$
 
$
(746,000
)
Contract consultants
   
341,000
   
   
(341,000
)
Production facilities costs
   
122,000
   
   
(122,000
)
Supplies
   
17,000
   
   
(17,000
)
Gain on equipment lease settlement
   
   
   
 
Other
   
75,000
   
   
(75,000
)
Total
 
$
1,301,000
 
$
 
$
(1,301,000
)
 
22

 
We had no personnel, contract consultants’ charges, production facilities costs and supplies in 2006, and to the extent incurred during 2005 were greatly reduced over prior years primarily due to our cessation of operations and implementation of other aspects of our restructuring plan which was initiated in the three months ending June 30, 2005. The only research and development costs incurred in 2006 related solely to patent and related intellectual property protection activities for Imagent, in furtherance of our restructuring plan.
 
 Our research and development expenses related to Imagent were approximately $1,301,000 and $-0- for the 2005 and 2006 fiscal years, respectively. We have incurred a total of $6,842,000 in development expense for Imagent. 
 
Selling, General and Administrative Expense
 
The following is a summary of the major cost categories in selling general and administrative expenses (all amounts approximate):

 
 
Fiscal Year
Ended
December 31,
2005
 
Fiscal Year
Ended
December 31,
2006
 
Increase/
(Decrease)
2005 to 2006
 
Personnel
 
$
845,000
 
$
   
(845,000
)
Contract consultants
   
646,000
   
108,000
   
(538,000
)
Stock based compensation
   
1,078,000
   
42,000
   
(1,036,000
)
Legal and accounting
   
1,324,000
   
191,000
   
(1,133,000
)
Fees
   
1,675,000
   
   
(1,675,000
)
Facilities costs
   
937,000
   
12,000
   
(925,000
)
Insurance
   
476,000
   
173,000
   
(303,000
)
Commission related to earned license revenues
   
    48,000     48,000  
Royalties related to earned license revenues
   
    28,000     28,000  
Depreciation & amortization
   
618,000
   
   
(618,000
)
Amortization of purchase technology
   
1,303,000
   
   
(1,303,000
)
Patent costs
    148,000     157,000     9,000  
Other
   
396,000
   
31,000
   
(365,000
)
Total
 
$
9,446,000
 
$
790,000
   
(8,656,000
)
 
Personnel, contract consultants, facilities and insurance expenses decreased from 2005 to the comparable 2006 period, primarily due to our efforts to cut expenses and implement our restructuring plan.
 
 There were no personnel costs in 2006, as all employee relationships were terminated in 2005 as part of our restructuring activities. Personnel costs in 2005 include a contractually obligated bonus of $206,250 to our then chief executive officer incurred in 2004, which remains unpaid in its entirety at December 31, 2006. In addition, the personnel costs incurred for 2005 include approximately $329,000 in net one-time charges for severance and incentive retention bonuses. Gross charges incurred during 2005 totaled $389,000, but was reduced by the offsetting waiver of a previously accrued bonus of $60,000 related to a prior period. Of the gross charges of $389,000, of which $34,000 represented nominal severance incentives paid to former staff in order to induce orderly restructuring of our affairs, $275,000 reflects the accrual of a one year salary severance obligation contractually owed to our former chief executive officer whose employment with us ended on May 31, 2005 (and which also remains unpaid in its entirety at December 31, 2006) and $80,000 in incentive retention bonuses issued in favor of our chief operating officer and one other employee who were both deemed integral to conducting the orderly restructuring of our operations in a manner necessary to preserve net asset values for creditors and shareholders.
 
23

 
 Contract consultant charges decreased significantly from the fiscal year ended December 31, 2005 for the comparable 2006 period, due to the restructuring plan commenced in the second quarter of 2005.
 
 Stock based compensation expense decreased during the fiscal year ended December 31, 2006 over the comparable 2005 period. The 2005 charges were significantly larger primarily due to the accelerated expense recognition of approximately 88,290 option-shares which had previously been issued at then below-market strike process to our former chief executive officer, but which became 100% vested on his employment termination date of May 31, 2005. Expenses recognized in 2006 related to options granted in prior period to two board members as compensation for their service on our board of directors.
 
 Legal and accounting expense decreased significantly from the fiscal year ended December 31, 2006 from the comparable period in 2005. Costs incurred during 2006 were relatively lower as a result of completing or curtailing litigation and registration activities. Costs incurred in 2006 related primarily to contract-related matters (including the amended and restated license agreement with Kyosei effective as of November 13, 2006) and SEC compliance and related reporting matters.
 
 There were no expenditures on fees in 2006. Fees incurred during the fiscal year ended December 31, 2005 related almost entirely to late registration penalties that began accruing in January 2005 for shares for which we have filed two registration statements.  Given our financial circumstances and goal to maximize the funds available to creditors, we withdrew those registration statements. We have stopped accruing penalty shares for investors that had registration rights, either by agreement (as with Oxford Bioscience Partners IV L.P., MRNA Fund II, L.P. and Mi3 L.P.) or because the shares originally issued became salable under Rule 144.
 
 Commissions of $48,000 and royalties of $28,000 incurred in 2006 (none in 2005) related solely to the amended and restated license agreement with Kyosei effective as of November 13, 2006, net of that portion which was reimbursed by Alliance as their pro rata portion (approximately $4,000 and $2,000, respectively).
 
Depreciation and amortization costs incurred during 2005 related to only that portion expensed up through April 2005, as after that date we took our equipment out of use and prepared for public auction, which was conducted in June 2005, in accordance with our restructuring activities.
 
24

 
Loss on Disposal of Property, Plant and Equipment

During the year ended December 31, 2005, furniture, fixtures and equipment with a net book value of $550,689 ($1,827,859 cost, less $1,083,993 accumulated depreciation and amortization and less $193,177 allowance for impairment reserve) was sold or otherwise disposed of for $324,384 in net proceeds, resulting in a loss on disposal of equipment totaling $226,305. No such losses were incurred in 2006, as all equipment was disposed in 2005 in accordance with our restructuring activities.
 
Impairment Losses
 
In 2006, we recorded impairment losses totaling $1,000,000 against the remaining net value of our Purchased Technology, after completing the amended and restated license agreement with Kyosei for which we received gross compensation of $1,200,000, after which we gave further consideration as to the likelihood of concluding any similar transactions, which we deem unlikely in the near term.
 
In 2005, we recorded the impairment losses totaling a net amount of approximately $7,506,500 in order to reflect fair market value of certain assets for which we were able to make reasonable estimations, all as a result of our restructuring activities (all amounts approximate):
 
·  
Leasehold improvements - $3,072,500 (reduced to a remainder carrying value of $20,000 at June 30, 2005, an amount which was associated with a pending transaction that was subsequently concluded by December 31, 2005 for which we received cash consideration);
 
·  
Equipment - $193,000 (reduced to a remainder carrying value of $31,220 at June 30, 2005, an amount which was associated with a pending transaction that was subsequently concluded by December 31, 2005 for which we received cash consideration);
 
·  
Technology license - $570,500 (reduced to a remainder carrying value of $102,500 at June 30, 2005, an amount which was associated with a pending transaction that was subsequently concluded by December 31, 2005 for which we received cash consideration);
 
·  
Purchased Technology - $11,373,500 (reduced to a remainder carrying value of $1,000,000 at December 31, 2005); and
 
·  
Deferred royalties - $416,500 (reduced to a carrying value of $-0- at December 31, 2005).
 
25

 
In addition, the above impairment charges, totaling approximately $15,626,000, were offset by the adjustment of previously deferred revenue totaling approximately $8,119,500, resulting in net impairment charges recognized in 2005 amounting to approximately $7,506,500. 
 
Investment and Other Income

Investment and other income for the years ended December 31, 2005 and 2006 was $42,875 and $12,711, respectively. Investment and other income for 2006 decreased from the comparable period in 2005, primarily due to the cessation of the production and sales of Imagent in 2005. Our investment and income in 2006 consisted solely of interest earnings on our cash reserves, whereas only $3,952 was attributed to interest earnings in 2005. 
 
Gain on Extinguishment of Debt

In 2005, we obtained a settlement of obligations totaling $114,802 in exchange for cash payments of $10,360, resulting in a gain on the extinguishment of debt of $104,442. In 2006, we obtained a settlement of obligations totaling $361,242 in exchange for cash payments of $36,321, resulting in a gain on the extinguishment of debt of $324,921. We continue to negotiate with creditors from time to time, with the objective of achieving compromises with similar discounts, to the extent our cash reserves permit.
 
Interest Expense

Interest expense was $90,857 and $97,187 for the years ended December 31, 2005 and 2006, respectively. There as no change in the underlying amounts of obligations of interest-bearing notes receivable and other interest bearing obligations during 2006, which is attributable to royalties accrued from Schering AG (with an adjustable interest rate feature), obligations assumed in the Alliance transactions, and amounts owed to certain shareholders. No interest payments have been made in either year.
 
Preferred Stock
 
There were no preferred stock dividend obligations in either 2005 or 2006, as to any series of Preferred Stock.
 
Loss Attributable to Common Shareholders
 
As a result of the above factors, the net loss applicable to common shareholders was $17,697,883 and $349,816 for the years ended December 31, 2005 and 2006 respectively. Basic and diluted loss per common share was $2.95 and $$0.05, respectively, for these periods. Weighted average shares utilized in these calculations were 6,003,141 and 6,962,456, respectively. The increase in weighted shares outstanding was due primarily to the issuance of shares in settlement of penalties and late registration fees during 2005, all of which were outstanding for the duration of 2006.  There were no additional issuances of common stock made in 2006, other than related to rounding by one share associated with the continued exchange of common shares pursuant to the reverse stock split effected in 2005.
 
26

 
PLAN OF OPERATION 
 
In April and May 2005, we adopted a restructuring plan that resulted in cessation or suspension of substantially all operations, including significant employee reduction-in-force, sale of excess equipment, suspension of manufacturing and clinical activities, cessation of current selling activities, vacating its premises, and the sale of certain of our technology. We also helped locate a third party to occupy our facility, and accordingly were able to negotiate a lease termination agreement which was concluded in July 2005. However, abandoning our facility resulted in us no longer being able to manufacture Imagent ourselves. We have also sold our equipment and other licensed technology assets except for the Imagent Purchased Technology.
 
 Therefore, we are currently unable to operate in a manner that would allow us to further develop or promote the Imagent product. In August 2005, we notified the FDA that we suspended any activity related to the Investigational New Drug Application. We will focus our limited resources primarily on preserving the value of the Purchased Technology, to the extent possible, and exploring various options concerning our business, including joint venturing, licensing or selling our Imagent Purchased Technology and other possible strategic transactions. We no longer have current human, financial and other resources available to us at this time to carry out our original business plan or fully develop and commercialize Imagent on our own. Our plan is to effectuate the restructuring plan described above.
 
We will continue to investigate with other parties as to potential transactions that would create additional revenues (license, royalty or other form of revenues) from the licensing or sale of Imagent. In addition, we plan to maintain our intellectual property and patent estate related to Imagent, including conducting those additional activities necessary to preserve the value of this asset for potential other licensing or related strategic transactions. Our activities will also include those actions necessary to meet our regulatory, financial and tax reporting obligations. When opportunities present themselves, we will negotiate with certain creditors and execute related settlement agreements with those certain creditors who have agreed to take fractional payments for their liability claims in exchange for a full and final release of the related indebtedness, which will result in gains from debt extinguishment for our benefit. We have no current plans to hire any staff or to pursue any manufacturing, marketing or distribution activities.
 
CONTRACTUAL OBLIGATIONS
 
The following table summarizes our approximate contractual obligations as of December 31, 2006 and the effect such obligations are expected to have on our liquidity and cash flow for future periods:

 
 
Total
Obligations
All Years
 
2007
 
2008
 
2009
 
2010
 
Imagent purchase obligations and related notes (remaining)
 
$
808,000
 
$
808,000
 
$
 
$
 
$
 
 
                     
Notes payable
   
192,000
   
192,000
   
   
   
 
 
                     
Accrued royalty liabilities
   
432,000
   
432,000
   
   
   
 
 
               
 
     
Severance and unpaid bonus to former CEO
   
481,000
   
481,000
   
   
   
 
 
                     
Settlement amounts owed and guaranteed pursuant to equipment lease settlement
   
493,000
   
493,000
   
   
   
 
 
                     
Other liabilities- past due
   
696,000
   
696,000
   
   
   
 
 
                     
Accounts payable- ($1,452,000 past due)
   
1,501,000
   
1,501,000
   
   
   
 
 
                     
Total contractual cash obligations
 
$
4,603,000
 
$
4,603,000
 
$
 
$
 
$
 
 
27

 
We were released from operating lease obligations totaling approximately $2,285,000, which were related to our facilities lease at 6175 Lusk Boulevard in San Diego, pursuant to a lease termination agreement executed July 19, 2005 and made effective on or about July 31, 2005.
 
 As of December 31, 2006, we have not entered into any purchase orders for capital equipment.  
 
SIGNIFICANT ESTIMATES 
 
Our discussion and analysis of our financial condition and results of operations are based on our consolidated financial statements, which have been prepared in accordance with generally accepted accounting principles in the United States. The preparation of these financial statements requires us to make estimates and judgments that affect the reported amounts of assets, liabilities and expenses. On an ongoing basis, we evaluate our estimates and judgments, including those related to evaluation of impairment analysis of long-lived assets. We based our estimates on historical experience and on various other assumptions that we believe to be reasonable under the circumstances, the results of which form the basis for making judgments about the carrying values of assets and liabilities that are not readily apparent from other sources. Actual results may differ from these estimates under different assumptions or conditions. We believe our most significant estimates relate to the impairment analysis we perform on long-lived assets to assess when a change in circumstances indicates that the carrying value may not be recoverable and we estimate the probable future cash flows related to that asset. We base our valuation assumptions on currently available information including estimates of market size and penetration, pricing, competitive threats and general operating expenses. These estimates may change and such changes may impact future estimates of carrying value.
 
 We consider the valuation of our investment in the Imagent Business to be a significant estimate. The carrying value of the Imagent Business at December 31, 2005 was approximately $1,000,000, net of accumulated depreciation and amortization and allowances for impairment, including assets purchased subsequent to the acquisition of the Imagent Business. On an annual basis (or more often as conditions may warrant), we continue to evaluate the carrying value of the Imagent Business and make any necessary adjustments (which we did again at December 31, 2006). Our valuation assumptions have been based on currently available information including estimates of market size and penetration, pricing, competitive threats and general operating expenses. These estimates may change and such changes may impact future estimates of carrying value.
 
28

 
At December 31, 2006, after giving consideration to a) the amended and restated license agreement with Kyosei, for which we received gross proceeds of $1,200,000 in additional earned license revenue in November and December 2006, and b) the likelihood of executing any similar agreements in the near term, we recorded an additional and final charge for impairment losses on the Imagent Purchased Technology in the amount of $1,000,000, reducing the carrying value on our balance sheet as of that date to $-0-.
 
RECENT ACCOUNTING PRONOUNCEMENTS
 
In March 2006, the FASB issued Statement No. 156, “Accounting for Servicing of Financial Assets, an amendment of FASB Statement No. 140” (“SFAS No. 156”). SFAS No. 156 amends SFAS No. 140 to require that all separately recognized servicing assets and liabilities in accordance with SFAS No. 140 be initially measured at fair value, if practicable. Furthermore, this standard permits, but does not require, fair value measurement for separately recognized servicing assets and liabilities in subsequent reporting periods. SFAS No. 156 is also effective for the Company beginning January 1, 2007; however, the standard is not expected to have any impact on the Company’s financial position, results of operation or cash flows.
 
In June 2006, the FASB issued Interpretation No. 48, “Accounting for Uncertainty in Income Taxes - an interpretation of FASB Statement No. 109,” (“FIN 48”). FIN 48 clarifies the accounting for uncertainty in tax positions and requires that a Company recognize in its financial statements the impact of a tax position, if that position is more likely than not of being sustained on audit, based on the technical merits of the position. The provisions of FIN 48 are effective for fiscal years beginning after December 15, 2006. The adoption of FIN 48 is not expected to have any impact on the Company’s financial statements.
 
In September 2006, the FASB issued Statement No. 157, “Fair Value Measurements” (“SFAS No. 157”). SFAS 157 defines fair value, establishes a framework for measuring far value in generally accepted accounting principles and expands related disclosures about fair value measurements. This Statement focuses on creating consistency and comparability in fair value measurements. SFAS No. 157 is effective for the Company beginning January 1, 2008, including any interim reporting periods. The Company is currently evaluating the impact of adopting SFAS No. 157 on its financial statements.
 
In September 2006, the SEC Staff issued Staff Accounting Bulletin No. 108 (“SAB 108”) to require registrants to quantify financial statement misstatements that have been accumulating in their financial statements for years and to correct them, if material, without restating. Under the provisions of SAB 108, financial statement misstatements are to be quantified and evaluated for materiality using both balance sheet and income statement approaches. SAB 108 is effective for fiscal years ending after November 15, 2006. The adoption of SAB 108 did not have a material impact on our financial statements.

29

 
 
ITEM 7. FINANCIAL STATEMENTS.
 
INDEX TO FINANCIAL STATEMENTS
 
 
 
Page
 
 
 
 
 
Report of Independent Registered Public Accounting Firm
   
31
 
 
       
FINANCIAL STATEMENTS:
       
 
       
Consolidated Balance Sheets as of December 31, 2005 and 2006
   
33
 
 
       
 Consolidated Statements of Operations for the Years Ended
   
 
 
December 31, 2005 and 2006 and for the Period from November 3, 1996
       
(inception) through December 31, 2006
   
34
 
 
       
Consolidated Statements of Shareholders’ Equity (Deficit) for
   
 
 
the Period from November 3, 1996 (inception) through
       
December 31, 2006
    35  
 
       
Consolidated Statements of Cash Flows for the Years Ended
   
 
 
December 31, 2005 and 2006 and for the Period from
       
November 3, 1996 (inception) through December 31, 2006
   
41
 
 
     
Notes to Consolidated Financial Statements
   
44
 
 
30

 

REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM


To the Board of Directors and Stockholders of
IMCOR Pharmaceutical Co.
 
We have audited the accompanying balance sheets of IMCOR Pharmaceutical Co. (the “Company”), a Development Stage Company, as of December 31, 2006 and 2005, and the related statements of operations, stockholders' deficit, and cash flows for the years then ended, and for the period from November 3, 1996 (inception) through December 31, 2006. These financial statements are the responsibility of the Company's management. Our responsibility is to express an opinion on these financial statements based on our audit.

We conducted our audits in accordance with the standards of the Public Company Accounting Oversight Board (United States).  Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements are free of material misstatement.  The Company is not required to have, nor were we engaged to perform, an audit of its internal control over financial reporting. Our audit included consideration of internal control over financial reporting as a basis for designing audit procedures that are appropriate in the circumstances, but not for the purpose of expressing an opinion on the effectiveness of the Company’s internal control over financial reporting. Accordingly, we express no such opinion.  An audit also includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial statements, assessing the accounting principles used and significant estimates made by management, as well as evaluating the overall financial statement presentation.  We believe that our audits provide a reasonable basis for our opinion.

In our opinion, the financial statements referred to above present fairly, in all material respects, the financial position of IMCOR Pharmaceutical Co. as of December 31, 2006 and 2005, and the results of its operations and its cash flows for the years then ended, and for the period from November 3, 1996 (inception) through December 31, 2006, in conformity with accounting principles generally accepted in the United States of America.

As discussed in Note 2 to the financial statements, the Company changed its method of accounting for stock-based compensation, effective January 1, 2006, as a result of the adoption of Statement of Financial Accounting Standards No. 123R, Share-Based Payments.
 
31

 

The accompanying financial statements have been prepared assuming that the Company will continue as a going concern. As discussed in Note 2 to the financial statements, the Company has reported recurring losses from operations through December 31, 2006 and had a working capital deficit at December 31, 2006. These factors raise substantial doubt about the Company’s ability to continue as a going concern. Management’s plans as to these matters are described in Note 2. The accompanying financial statements do not include any adjustments that might result from the outcome of this uncertainty.
 
SQUAR, MILNER, PETERSON, MIRANDA & WILLIAMSON, LLP
 
San Diego, California
April 13, 2007
 
32

 

IMCOR PHARMACEUTICAL CO. AND SUBSIDIARIES
(A Development Stage Company)
CONSOLIDATED BALANCE SHEETS

 
 
December 31,
2005
 
December 31,
2006
 
 
 
 
 
 
 
ASSETS
 
 
 
 
 
 
 
 
 
 
 
Current Assets:
 
 
 
 
 
Cash and cash equivalents
 
$
717,024
 
$
1,309,498
 
Prepaid expenses and other current assets
   
144,535
   
30,648
 
 Total current assets
   
861,559
   
1,340,146
 
 
           
 
           
Other assets:
           
Purchased technology, net
   
1,000,000
   
 
 
   
1,000,000
   
 
 
 
$
1,861,559
 
$
1,340,146
 
 
LIABILITIES AND SHAREHOLDERS’ DEFICIT
 
 
 
 
 
 
 
 
 
 
 
Current Liabilities:
 
 
 
 
 
  Notes payable - unsecured
 
$
192,233
 
$
192,233
 
  Accounts payable
   
1,841,667
   
1,500,940
 
  Accrued expenses and assumed acquisition obligations
   
1,888,161
   
1,985,348
 
  Accrued royalty fees
   
401,946
   
431,946
 
  Accrued equipment lease obligation
   
492,984
   
492,984
 
    Total current liabilities
   
4,816,991
   
4,603,451
 
 
           
Commitments and contingencies (Notes 3, 8 and 13)
             
 
           
SHAREHOLDERS’ DEFICIT:
           
Preferred stock, $0.01 par value; 5,000,000 shares authorized
           
    Series A preferred stock: 4,500 shares
           
      authorized, issued and outstanding as of December 31, 2005
           
      and 2006, respectively; $1,000 liquidation preference per share
           
      ($4,500,000 in aggregate as of December 31, 2005
           
      and 2006)
   
45
   
45
 
Common stock, $0.001 par value; 200,000,000 shares authorized;
           
  6,962,455 and 6,962,456 shares issued and outstanding
           
  as of December 31, 2005 and 2006, respectively
   
6,962
   
6,962
 
Additional paid-in capital
   
87,926,777
   
87,968,720
 
Deficit accumulated during the development stage
   
(90,889,216
)
 
(91,239,032
)
 
   
(2,955,432
)
 
(3,263,305
)
 
           
 
 
$
1,861,559
 
$
1,340,146
 
 
See notes to consolidated financial statements.

33

 
 
IMCOR PHARMACEUTICAL CO. AND SUBSIDIARIES
(A Development Stage Company)
CONSOLIDATED STATEMENTS OF OPERATIONS
 
   
Year Ended
December 31,
2005
 
Year Ended
December 31,
2006
 
Period from
Inception
(November 3,
1996) to
December 31,
2006
 
 
 
 
 
 
 
 
 
License revenue
 
$
725,575
 
$
1,200,000
 
$
2,280,515
 
 
                 
Operating expenses:
                 
Research and development
   
1,301,149
   
   
11,981,528
 
Selling, general and administrative
   
9,445,898
   
790,261
   
56,514,811
 
Restructuring charges
   
   
   
1,541,455
 
Provision for future lease payments
   
   
   
1,264,208
 
Loss on disposal of property, plant and equipment
   
226,305
   
   
226,305
 
Impairment losses, net
   
7,506,566
   
1,000,000
   
8,781,045
 
Total operating expenses
   
18,479,918
   
1,790,261
   
80,309,352
 
 
                 
Operating loss
   
(17,754,343
)
 
(590,261
)
 
(78,028,837
)
 
                 
Loss from joint venture
   
   
   
(14,518,000
)
Investment and other income
   
42,875
   
12,711
   
1,507,585
 
Gain on extinguishment of debt
   
104,442
   
324,921
   
429,363
 
Interest expense
   
(90,857
)
 
(97,187
)
 
(1,729,794
)
Loss from continuing operations
   
(17,697,883
)
 
(349,816
)
 
(92,339,683
)
 
                 
Discontinued operations:
                 
Operating loss from therapeutic business
   
   
   
(10,679,101
)
Gain from split-off of therapeutic business
   
   
   
11,779,752
 
   
   
   
1,100,651
 
 
                 
Net loss
 
$
(17,697,883
)
$
(349,816
)
$
(91,239,032
)
 
                 
Basic and Diluted loss per common share from
               
continuing operations
 
$
(2.95
)
$
(0.05
)
   
Basic and Diluted Loss per common share
               
from discontinued operations
 
$
 
$
     
Basic and diluted net loss per common share
 
$
(2.95
)
$
(0.05
)
   
 
               
Weighted average number of common shares
               
outstanding- basic and diluted
   
6,003,141
   
6,962,456
     

See notes to consolidated financial statements.

34

 
 
IMCOR PHARMACEUTICAL CO. AND SUBSIDIARIES
(A Development Stage Company)
CONSOLIDATED STATEMENTS OF SHAREHOLDER EQUITY (DEFICIT)

 
 
 
 
 
 
Common
 
 
 
Deficit
 
 
 
 
 
Preferred Stock
 
 
 
 
 
Stock
 
Unearned
 
Additional
 
Accumulated
 
 
 
 
 
Series A
 
Series B
 
Common Stock
 
Members’
 
To Be
 
Compen-
 
Paid-in
 
Development
 
 
 
 
 
Shares
 
Amount
 
Shares
 
Amount
 
Shares
 
Amount
 
Capital
 
Issued
 
sation
 
Capital
 
Stage
 
Total
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Contribution of capital
   
 
$
   
 
$
   
 
$
 
$
7,268
 
$
 
$
 
$
 
$
 
$
7,268
 
Net loss for the period ended December 31, 1996
   
   
   
   
   
   
   
(1,779
)
 
   
   
   
   
(1,779
)
Balance, at December 31, 1996
   
   
   
   
   
   
   
5,489
   
   
   
   
   
5,489
 
 
                                                 
Contribution of capital
   
   
   
   
   
   
   
   
   
   
   
   
 
Net loss for the period January 1, 1997 to May 15, 1997
   
   
   
   
   
   
   
3,511
   
   
   
   
(3,511
)
 
 
Balance, at May 15, 1997
   
   
   
   
   
   
   
9,000
   
   
   
   
(3,511
)
 
5,489
 
                                                 
Issuance of common stock
   
   
   
   
   
78,910
   
79
   
   
   
   
1,803,371
   
   
1,803,450
 
Effect of recapitalization and merger
   
   
   
   
   
371,090
   
371
   
(9,000
)
 
   
   
1,210,816
   
1,732
   
1,203,919
 
Cost associated with recapitalization and merger
   
   
   
   
   
   
   
   
   
   
(371,111
)
 
   
(371,111
)
Net loss for the period May 16, 1997 to December 31, 1997
   
   
   
   
   
   
   
   
   
   
   
(554,702
)
 
(554,702
)
 
                                                 
Balance, at December 31, 1997
   
   
   
   
   
450,000
   
450
   
   
   
   
2,643,076
   
(556,481
)
 
2,087,045
 
 
                                                 
Issuance of common stock
   
   
   
   
   
10,938
   
11
   
   
   
   
6,999,989
   
   
7,000,000
 
Costs associated with common stock issuance
   
   
   
   
   
   
   
   
   
   
(50,000
)
 
   
(50,000
)
Options issued to consultants
   
   
   
   
   
   
   
   
   
   
45,446
   
   
45,446
 
Net loss for the year ended December 31,  1998
   
   
   
   
   
   
   
   
   
   
   
(1,973,913
)
 
(1,973,913
)
 
                                                 
Balance, at December 31, 1998
   
   
   
   
   
460,938
   
461
   
   
   
   
9,638,511
   
(2,530,394
)
 
7,108,578
 
 
35

 

IMCOR PHARMACEUTICAL CO. AND SUBSIDIARIES
(A Development Stage Company)
CONSOLIDATED STATEMENTS OF SHAREHOLDER EQUITY (DEFICIT) (Continued)
 
               
Common
         
Deficit
     
   
Preferred Stock
         
Stock
 
Unearned
 
Addtional
 
Accumulated
     
   
Series A
 
Series B
 
Common Stock
 
Members’
 
To Be
 
Compen-
 
Paid-in
 
Development
     
   
Shares
 
Amount
 
Shares
 
Amount
 
Shares
 
Amount
 
Capital
 
Issued
 
sation
 
Capital
 
Stage
 
Total
 
Exercise of stock options
   
   
   
   
   
56
   
   
   
   
   
50,063
   
   
50,063
 
Issuance of warrants and options
   
   
   
   
   
   
   
   
   
   
3,664,749
   
   
3,664,749
 
Issuance of common stock
   
   
   
   
   
6,298
   
6
   
   
   
   
6,082,648
   
   
6,082,654
 
Issuance of preferred stock
   
12,015
   
120
   
   
   
   
   
   
   
   
11,578,839
   
   
11,578,959
 
Reclassification of Series A shares as mezzanine equity in accordance with EITF D-98
   
(12,015
)
 
(120
)
 
   
   
   
   
   
   
   
(11,578,839
)
 
   
(11,578,959
)
 
                                                 
Net loss for the year ended December 31,  1999
   
   
   
   
   
   
   
   
   
   
   
(6,052,841
)
 
(6,052,841
)
 
                                                 
Balance, at December 31, 1999
   
   
   
   
   
467,292
   
467
   
   
   
   
19,435,971
   
(8,583,235
)
 
10,853,203
 
 
                                                 
Stock option compensation
   
   
   
   
   
   
   
   
   
   
125,020
   
   
125,020
 
Issuance of warrants and options
   
   
   
   
   
   
   
   
   
   
1,366,050
   
   
1,366,050
 
Issuance of preferred stock dividend
   
841
   
8
   
   
   
   
   
   
   
   
(8
)
 
   
 
Issuance of preferred stock
   
   
   
337,056
   
3,370
   
   
   
   
   
   
5,272,970
   
   
5,276,340
 
Beneficial accretion of Series A shares reclassified as mezzanine equity
   
   
   
   
   
   
   
   
   
   
(240,464
)
 
   
(240,464
)
Net loss for the year ended December 31,  2000
   
   
   
   
   
   
   
   
   
   
   
(10,787,062
)
 
(10,787,062
)
 
                                                 
Balance, at December 31, 2000
   
841
   
8
   
337,056
   
3,370
   
467,292
   
467
   
   
   
   
25,959,539
   
(19,370,297
)
 
6,593,087
 
 
                                                 
Stock option compensation
   
   
   
   
   
   
   
   
   
   
64,729
   
   
64,729
 
Issuance of common stock for cash
   
   
   
   
   
2,462
   
2
   
   
   
   
418,721
   
   
418,723
 
 
36

 

IMCOR PHARMACEUTICAL CO. AND SUBSIDIARIES
(A Development Stage Company)
CONSOLIDATED STATEMENTS OF SHAREHOLDER EQUITY (DEFICIT) (Continued)
 
               
Common
 
 
 
 
 
Deficit
 
 
 
 
 
Preferred Stock
 
 
 
 
 
Stock
 
Unearned
 
Additional
 
Accumulated
 
 
 
 
 
Series A
 
Series B
 
Common Stock
 
Members’
 
To Be
 
Compen-
 
Paid-in
 
Development
 
 
 
 
 
Shares
 
Amount
 
Shares
 
Amount
 
Shares
 
Amount
 
Capital
 
Issued
 
sation
 
Capital
 
Stage
 
Total
 
Issuance of common stock in satisfaction of anti-dilution provision
   
   
   
   
   
9,543
   
10
   
   
   
   
(10
)
 
   
 
Issuance of preferred stock dividend
   
   
   
20,224
   
202
   
   
   
   
   
   
(202
)
 
   
 
Beneficial accretion of Series A shares reclassified as mezzanine equity
   
   
   
   
   
   
   
   
   
   
(195,577
)
 
   
(195,577
)
Net loss for the year ended December 31,  2001
   
   
   
   
   
   
   
   
   
   
   
(9,723,016
)
 
(9,723,016
)
Balance, at December 31, 2001
   
841
   
8
   
357,280
   
3,572
   
479,297
   
479
   
   
   
   
26,247,200
   
(29,093,313
)
 
(2,842,054
)
Stock option compensation
   
   
   
   
   
   
   
   
   
   
73,870
   
   
73,870
 
Issuance of warrants for service
   
   
   
   
   
   
   
   
   
   
322,000
   
   
322,000
 
Issuance of options in settlement of lawsuit
   
   
   
   
   
   
   
   
   
   
806,415
   
   
806,415
 
Employee compensation from stock options
   
   
   
   
   
   
   
   
   
   
988,184
   
   
988,184
 
Issuance of preferred stock dividends
   
   
   
40,194
   
402
   
   
   
   
   
   
(402
)
 
   
 
Conversion of Series B to common stock
   
   
   
(397,474
)
 
(3,974
)
 
21,116
   
21
   
   
   
   
3,953
   
   
 
Beneficial inducement costs for convertible debt converted
   
   
   
   
   
   
   
   
   
   
206,348
   
   
206,348
 
Conversion of line of credit with Élan to common stock
   
   
   
   
   
6,422
   
6
   
   
   
   
3,082,481
   
   
3,082,487
 
Conversion of line of credit with entity controlled by director of company to common stock
   
   
   
   
   
115,741
   
116
   
   
   
   
2,499,884
   
   
2,500,000
 
Retirement of common stock returned in shareholder transaction 
   
   
   
   
   
(256,855
)
 
(257
)
 
   
   
   
(12,226,062
)
 
   
(12,226,319
)
 
37

 

IMCOR PHARMACEUTICAL CO. AND SUBSIDIARIES
(A Development Stage Company)
CONSOLIDATED STATEMENTS OF SHAREHOLDER EQUITY (DEFICIT) (Continued)

                   
Common
         
Deficit
     
 
 
Preferred Stock
 
 
 
 
 
 
 
Stock
 
Unearned
 
Additional
 
Accumulated
 
 
 
 
 
Series A
 
Series B
 
Common Stock
 
Members’
 
To Be
 
Compen-
 
Paid-in
 
Development
 
 
 
 
 
Shares
 
Amount
 
Shares
 
Amount
 
Shares
 
Amount
 
Capital
 
Issued
 
sation
 
Capital
 
Stage
 
Total
 
Issuance of common stock for cash
   
   
   
   
   
441,153
   
441
   
   
   
   
9,141,460
   
   
9,141,901
 
Net loss for the year ended December  31, 2002
   
   
   
   
   
   
   
   
   
   
   
348,119
   
348,119
 
 
                                                 
Balance, at December  31, 2002
   
841
   
8
   
   
   
806,874
   
806
   
   
   
   
31,145,331
   
(28,745,194
)
 
2,400,951
 
Issuance of common stock for cash
   
   
   
   
   
1,389
   
1
   
   
   
   
29,999
   
   
30,000
 
Issuance of common stock for standstill agreement
   
   
   
   
   
37,500
   
38
   
   
   
   
1,173,712
   
   
1,173,750
 
Conversion of Series B to common stock
   
   
   
   
   
5
   
   
   
   
   
   
   
 
Options issued to consultants for services
   
   
   
   
   
   
   
   
   
   
9,200
   
   
9,200
 
Shares issued to consultant for services
   
   
   
   
   
3,438
   
4
   
   
   
   
132,258
   
   
132,262
 
Employee compensation from stock options
   
   
   
   
   
   
   
   
   
   
1,236,566
   
   
1,236,566
 
Shares issued in Technology Purchase
   
   
   
   
   
109,907
   
110
   
   
   
   
5,583,158
   
   
5,583,268
 
Shares to be issued in Technology Purchase
   
   
   
   
   
   
   
   
5,043,226
   
   
   
   
5,043,226
 
Shares previously subject to rescission
   
   
   
   
   
6,231
   
6
   
   
   
   
649,994
   
   
650,000
 
Shares issued to Xmark for penalties
   
   
   
   
   
4,941
   
5
   
   
   
   
163,671
   
   
163,676
 
Shares issued to Xmark for interest
   
   
   
   
   
1,082
   
1
   
   
   
   
48,596
   
   
48,597
 
Shares to be issued to Xmark  and other former Alliance creditors for interest and penalties
   
   
   
   
   
   
   
   
76,933
   
   
   
   
76,933
 
Options exercised through cashless exercise
   
   
   
   
   
1,861
   
2
   
   
   
   
(2
)
 
   
 
Xmark puttable shares classified as mezzanine equity
   
   
   
   
   
   
   
   
   
   
(1,969,668
)
 
   
(1,969,668
)
 
38

 

IMCOR PHARMACEUTICAL CO. AND SUBSIDIARIES
(A Development Stage Company)
CONSOLIDATED STATEMENTS OF SHAREHOLDER EQUITY (DEFICIT) (Continued)
 
                   
Common
         
Deficit
     
   
Preferred Stock
         
Stock
 
Unearned
 
Additional
 
Accumulated
     
   
Series A
 
Series B
 
Common Stock
 
Members’
 
To Be
 
Compen-
 
Paid-in
 
Development
     
   
Shares
 
Amount
 
Shares
 
Amount
 
Shares
 
Amount
 
Capital
 
Issued
 
sation
 
Capital
 
Stage
 
Total
 
Net loss for the year ended December  31, 2003
   
   
   
   
   
   
   
   
   
   
   
(22,773,504
)
 
(22,773,504
)
Balance, at December  31, 2003
   
841
   
8
   
   
   
973,228
   
973
   
   
5,120,159
   
   
38,202,815
   
(51,518,698
)
 
(8,194,743
)
 
                                                 
Shares issued to consultant for services
   
   
   
   
   
11,562
   
12
   
   
   
(10,500
)
 
43,675
   
   
33,187
 
Shares to be issued for legal fees
   
   
   
   
   
   
   
   
247,865
   
   
   
   
247,865
 
Employee compensation from stock options
   
   
   
   
   
   
   
   
   
   
959,283
   
   
959,283
 
Shares issued in Imagent Business purchase
   
   
   
   
   
99,276
   
99
   
   
(5,043,226
)
 
   
5,043,127
   
   
 
Shares issued for penalties
   
   
   
   
   
8,935
   
9
   
   
(107,513
)
 
   
244,460
   
   
136,956
 
Shares to be issued to Xmark and secured creditors for interest and penalties
   
   
   
   
   
   
   
   
252,357
   
   
   
   
252,357
 
Shares issued as payment for promissory notes
   
   
   
   
   
1,679,173
   
1,679
   
   
   
   
13,431,705
   
   
13,433,384
 
Shares issued for cash, net
   
   
   
   
   
1,268,750
   
1,269
   
   
   
   
9,323,731
   
   
9,325,000
 
Shares to be issued to investors for late registration
   
   
   
   
   
   
   
   
832,300
   
   
   
   
832,300
 
Issuance of stock in settlement of lease
   
   
   
   
   
30,829
   
31
   
   
   
   
586
   
   
617
 
Xmark puttable shares issued from mezzanine equity
   
   
   
   
   
   
   
   
   
   
1,969,668
   
   
1,969,668
 
Conversion of Series A to common stock
   
(841
)
 
(8
)
 
   
   
9,763
   
10
   
   
   
   
12,161,445
   
   
12,161,447
 
Retirement of puttable shares
   
   
   
   
   
(80,600
)
 
(81
)
 
   
(203,190
)
 
   
(1,575,176
)
 
   
(1,778,447
)
Adjust shares for prior rounding
   
   
   
   
   
   
   
   
   
   
   
   
 
Shares to be issued to consultants for services
   
   
   
   
   
   
   
   
22,000
   
   
   
   
22,000
 
Shares issued for cash, net
   
4,500
   
45
   
   
   
   
   
   
   
   
4,139,955
   
   
4,140,000
 
 
39


IMCOR PHARMACEUTICAL CO. AND SUBSIDIARIES
(A Development Stage Company)
CONSOLIDATED STATEMENTS OF SHAREHOLDER EQUITY (DEFICIT) (Continued)
 
                   
Common
         
Deficit
     
   
Preferred Stock
         
Stock
 
Unearned
 
Additional
 
Accumulated
     
   
Series A
 
Series B
 
Common Stock
 
Members’
 
To Be
 
Compen-
 
Paid-in
 
Development
     
   
Shares
 
Amount
 
Shares
 
Amount
 
Shares
 
Amount
 
Capital
 
Issued
 
sation
 
Capital
 
Stage
 
Total
 
Proceeds from contribution by shareholder
   
   
   
   
   
   
   
   
   
   
46,690
   
   
46,690
 
Warrants issued for services rendered
   
   
   
   
   
   
   
   
   
   
28,400
   
   
28,400
 
Net loss for the year ended December  31, 2004
   
   
   
   
   
   
   
   
   
   
   
(21,672,635
)
 
(21,672,635
)
Balance December 31, 2004
   
4,500
   
45
   
   
   
4,000,916
   
4,001
   
 
$
1,120,752
 
$
(10,500
)
 
84,020,364
   
(73,191,333
)
 
11,943,329
 
Shares issued for services
   
   
   
   
   
105,610
   
105
   
   
(269,865
)
 
10,500
   
269,760
   
   
10,500
 
Employee compensation from stock options
   
   
   
   
   
   
   
       
   
1,077,780
   
   
1,077,780
 
Shares issued for penalties
   
   
   
   
   
2,855,743
   
2,856
   
   
(850,887
)
 
   
2,516,623
   
   
1,668,592
 
Options issued in settlement of claim
   
   
   
   
   
   
   
   
   
   
42,250
   
   
42,250
 
Shares issued per round-up requirement related to reverse stock split
   
   
   
   
   
186
   
   
   
   
   
   
   
 
Net loss for the year ended December  31, 2005
   
   
   
   
   
   
   
   
   
   
   
(17,697,883
)
 
(17,697,883
)
Balance December 31, 2005
   
4,500
   
45
   
   
   
6,962,455
 
$
6,962
   
   
   
   
87,926,777
   
(90,889,216
)
 
(2,955,432
)
Employee compensation from stock options
   
   
   
   
   
   
   
       
   
41,943
   
   
41,943
 
Shares issued per round-up requirement related to reverse stock split
   
   
   
   
   
1
   
   
   
   
   
   
   
 
Net loss for the year ended December  31, 2006
   
   
   
   
   
   
   
   
   
   
   
(349,816
)
 
(349,816
)
Balance December 31, 2006
   
4,500
 
$
45
   
 
$
   
6,962,456
 
$
6,962
 
$
 
$
 
$
 
$
87,968,720
 
$
(91,239,032
)
$
(3,263,305
)
 
40

 

IMCOR PHARMACEUTICAL CO. AND SUBSIDIARIES
(A Development Stage Company)
CONSOLIDATED STATEMENTS OF CASH FLOWS
 
   
Year Ended
December 31,
2005
 
Year Ended
December 31,
2006
 
Period from
Inception
(November 3,
1996) to
December 31,
2006
 
CASH FLOWS FROM OPERATING ACTIVITIES:
 
 
 
 
 
 
 
Net loss
 
$
(17,697,883
)
$
(349,816
)
$
(91,239,032
)
Net gain from discontinued operations
   
   
   
(1,100,651
)
Adjustments to reconcile net loss to cash (used in)
                 
provided by operating activities:
                 
Depreciation and amortization
   
1,920,667
   
   
8,406,351
 
Loss on disposal of property, plant and equipment
   
226,305
   
   
262,529
 
Gain on sale of marketable securities
   
   
   
(18,503
)
United States Treasury Notes amortization
   
   
   
12,586
 
Stock based compensation
   
1,077,780
   
41,943
   
5,003,342
 
Gain on extinguishment of debt
   
(104,442
)
 
(324,921
)
 
(429,363
)
Gain from equipment lease settlement
   
   
   
(126,257
)
License revenue deferred
   
1,000,000
   
   
9,000,000
 
Recognition of deferred license revenue
   
(725,575
)
 
   
(1,080,515
)
Amortization of deferred royalties expense
   
41,667
   
   
83,334
 
Valuation impairment allowances
   
7,506,566
   
1,000,000
   
8,781,045
 
Beneficial inducement costs for convertible notes
   
   
   
206,348
 
Issuance of warrants for services rendered
   
   
   
4,345,491
 
Issuance of stock options in settlement of lawsuit
   
   
   
806,415
 
Issuance of stock for standstill agreement
   
   
   
1,173,750
 
Issuance of stock for services rendered
   
10,500
   
   
445,814
 
Issuance of stock for interest payments and penalties
   
1,668,592
   
   
3,179,410
 
Equity in loss of affiliate
   
   
   
14,518,000
 
Changes in operating assets and liabilities:
                 
Accounts receivable
   
33,916
   
   
 
Prepaid expenses and other current assets
   
298,267
   
113,887
   
(30,648
)
Deferred royalties expense
   
   
   
(500,000
)
Accounts payable
   
29,558
   
(15,806
)
 
2,073,942
 
Accrued expenses and assumed acquisition obligations
   
(58,944
)
 
127,187
   
(286,770
)
Accrued equipment lease obligation
   
   
   
1,050,589
 
Other
   
   
   
10,000
 
Net cash (used in) provided by continuing operating activities
   
(4,773,026
)
 
592,474
   
(35,452,793
)
 
                 
Net cash used in discontinued operations
   
   
   
(10,679,101
)
 
41

 
 
IMCOR PHARMACEUTICAL CO. AND SUBSIDIARIES
(A Development Stage Company)
CONSOLIDATED STATEMENTS OF CASH FLOWS (Continued)

 
 
Year Ended
December 31,
2005
 
Year Ended
December 31,
2006
 
Period from
Inception
(November 3,
1996) to
December 31,
2006
 
CASH FLOWS FROM INVESTING ACTIVITIES:
 
 
 
 
 
 
 
Sale of marketable securities
   
   
   
2,164,464
 
Purchases of marketable securities
   
   
   
(2,182,967
)
Purchases of United States Treasury Notes
   
   
   
(38,656,973
)
Sale of United States Treasury Notes
   
   
   
39,778,548
 
Purchase of property, plant and equipment
   
(3,040
)
 
   
(754,674
)
Proceeds from disposal of property, plant and equipment
   
344,384
   
   
492,135
 
Proceeds from disposal of technology license
   
102,500
   
   
102,500
 
Patent acquisition costs
   
   
   
(237,335
)
Investment in and advances to affiliate
   
   
   
(15,107,468
)
Increase in note receivable
   
   
   
(1,255,000
)
Decrease (increase) in deposits
   
324,750
   
   
(439,370
)
Purchase of Imagent business
   
   
   
(5,074,761
)
Net cash provided by (used in) investing activities
   
768,594
   
   
(21,170,901
)
 
                 
Net cash used in investing activities of discontinued operations
   
   
   
(1,306,676
)
 
                 
CASH FLOWS FROM FINANCING ACTIVITIES
                 
Principal payments on capital leases
   
   
   
(291,704
)
Net proceeds from issuance of equity and mezzanine equity
   
   
   
54,004,340
 
Capital contributions from shareholders
   
   
   
1,958,364
 
Principal payments on acquisition debt
   
   
   
(2,500,000
)
Principal payments on other debt
   
   
   
(3,350,641
)
Proceeds from issuance of debt
   
   
   
20,544,721
 
Payments on lease settlement obligation
   
   
   
(75,000
)
Cost of recapitalization
   
   
   
(371,111
)
Net cash provided by financing activities
   
   
   
69,918,969
 
 
                 
NET (DECREASE) INCREASE IN CASH AND CASH EQUIVALENTS
   
(4,004,432
)
 
592,474
   
1,309,498
 
CASH AND CASH EQUIVALENTS, BEGINNING OF YEAR
   
4,721,456
   
717,024
   
 
CASH AND CASH EQUIVALENTS, END OF YEAR
 
$
717,024
 
$
1,309,498
 
$
1,309,498
 
 
                 
SUPPLEMENTAL SCHEDULE OF CASH FLOWS
                 
INFORMATION
                 
Interest paid
 
$
 
$
 
$
481,769
 
 
42

 
 
IMCOR PHARMACEUTICAL CO. AND SUBSIDIARIES
(A DEVELOPMENT STAGE COMPANY)
CONSOLIDATED STATEMENTS OF CASH FLOWS (CONTINUED)

NON-CASH INVESTING AND FINANCING ACTIVITIES:
 
YEAR ENDED DECEMBER 31, 2006:
 
NONE
 
YEAR ENDED DECEMBER 31, 2005:
 
In February 2005, the Company issued modified options in further settlement of claims by a former employee. The modification of the options resulted in a $42,250 decrease of accrued expenses with a corresponding increase in additional paid-in capital.
 
In September 2005, the Company entered into two simultaneous agreements with GE Healthcare Ltd. and Alliance Pharmaceutical Corp., for among other things, a technology cross-license valued at $1,200,000 in favor of the Company, for which the Company received $1,000,000. By agreement, the balance, or $200,000, was paid directly by GE Healthcare Ltd. to Alliance Pharmaceutical Corp., resulting in a non-cash increase in license revenue deferred and a decrease in assumed acquisition liabilities.

43

 

IMCOR PHARMACEUTICAL CO. AND SUBSIDIARIES
(A DEVELOPMENT STAGE COMPANY)
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS (CONTINUED)
 
1. OPERATIONS AND RESTRUCTURING OVERVIEW
 
IMCOR Pharmaceutical Co. (formerly Photogen Technologies, Inc.) and Subsidiaries (the “Company”) is a development-stage pharmaceutical company previously focused on developing medical imaging pharmaceutical products. On February 5, 2004, the Company changed its name to IMCOR Pharmaceutical Co. to reflect the changed nature of the Company’s business to imaging pharmaceuticals.
 
One of the imaging agents is an FDA approved product, Imagent® (perflexane lipid microspheres) (“Imagent”), an ultrasound imaging contrast agent that was acquired in June 2003. Imagent had been previously approved for marketing by the FDA for use in patients with sub-optimal echocardiograms to opacify the left ventricle of the heart and improve delineation of the endocardial borders of the heart. Additionally, the Company had previously sought to expand the label indication for Imagent to myocardial perfusion imaging for the detection of coronary artery disease.
 
During the second quarter of 2005, the Company’s board of directors concluded that substantial additional capital resources required to fund its ongoing operations would not be forthcoming, and as more further described in Note 13, the Company has adopted and implemented an evolving restructuring plan that resulted in cessation or suspension of substantially all operations, including complete employee reduction-in-force, sale of excess equipment, suspension of manufacturing and clinical activities, cessation of current selling activities, vacating its premises, and the sale of certain of its technology. During the quarter ending September 30, 2005 the Company entered into a technology cross-license and two settlement agreements to resolve certain litigation and related disputes with other parties, as further described in Notes 3 and 8.
 
As a result of these restructuring activities, the Company is no longer able to operate in a manner that would allow it to further develop or promote the Imagent product on its own, and is currently evaluating its alternatives with respect to efforts to sell or otherwise maximize asset values related to the “Purchased Technology” (defined as the assets acquired on June 18, 2003 from Alliance Pharmaceutical Corp. (“Alliance”) which relate to the medical imaging business, including Imagent® (perflexane lipid microspheres), an FDA-approved product), and will continue to consider as alternatives the sale or license of it’s remaining assets, a merger or other material transaction. Such a transaction may include selling the Purchased Technology, a license or sale of the patent portfolio underlying the Purchased Technology, a manufacturing rights agreement, or another form of transaction. While such efforts as of December 31, 2006 have resulted in one such arrangement which yielded $1,200,000 in gross license revenues totaling $1,200,000 for the year then ended (see Note 13), no other definitive agreements have been reached nor transactions concluded. Although the Company is still contacting other interested or potentially interested parties, the attainment of a sale, license, development agreement or comparable transaction, while possible, is not likely to be developed and/or consummated in the near term.
 
44

 
The Company had two additional contrast agents in development for use in computed tomography (“CT”) and x - ray imaging with potential applications, (1) as a blood pool agent to diagnose diseased tissue in the cardiovascular system and other organs (PH-50), and (2) to diagnose cancer metastasizing into the lymphatic system (N1177). PH-50 and N1177 are iodinated nanoparticulate formulations and were still in early stages of development when the Company concluded a sale of the Technology License (to which these assets relate) for $102,500 in the third quarter 2005.
 
For the two years prior to the acquisition of the Imagent business in 2003, substantially all the Company’s research and development efforts were focused on the preclinical testing of PH-50. In addition, the Company had conducted research and development activities on the development of certain therapeutic photodynamic therapy applications and the development of a medical laser. These operations were split-off to the founding scientists as of November 12, 2002 and were recorded as discontinued operations in the financial statements.
 
The Company has previously realized only minimal revenues resulting from the licensing and sale of Imagent through the date of the suspension of selling activities in the second quarter of 2005. Such sales were intermittent and represented selective market efforts and were not necessarily indicative of future revenues or market penetration which might have been derived from the Company’s then current or prospective indications, and in the event adequate financial resources had been available to the Company.
 
Currently, the Company’s core business focus has evolved from an operating entity conducting research and development, manufacturing and limited selling activities, to one which is now developing alternatives with respect to maximizing the asset value for its remaining principal Purchased Technology asset, continuing to protect its patent portfolio, securing extended payment terms and/or release of creditor claims in exchange for significantly discounted settlement payments to its current creditors and conducting other compliance-related activities, including the submission of required filings with the Securities and Exchange Commission (SEC). Costs associated with conducting these activities will be incurred only so long as sufficient capital remains available, and with the overall primary objective remaining as that of maximizing net values available to unsecured creditors first and shareholders second.
 
2. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES:
 
LIQUIDITY AND BASIS OF PRESENTATION - GOING CONCERN: The accompanying consolidated financial statements are prepared assuming the Company is a going concern.  The Company has reported accumulated losses since inception of $91,239,032, and as of December 31, 2006, has a working capital deficit of approximately $3,263,305. In addition, and as indicated above and in more details in Note 13, a restructuring plan was implemented commencing in the second quarter of 2005.
 
To the extent that the Company was able to estimate with reasonable certainty the fair value of certain assets as a result of its restructuring activities, it provided for valuation impairment allowances during 2005 where necessary to reflect the estimated fair values, including property, leasehold improvements, and equipment and technology license. As a result, all non-working capital assets with the exception of the Purchased Technology asset and the related deferred royalty asset were written down to a carrying value of $-0- by September 30, 2005.
 
45

 
At December 31, 2005, and then again at December 31, 2006, the Company reassessed the carrying value of the Purchased Technology and the related deferred royalties asset, after taking into consideration the following factors:

 
The experience related to the continued solicitation of interest in alternative transactions involving the Company’s Purchased Technology, particularly in the aftermath of the settlement of its litigation and the corresponding entry into the technology cross-license and the two settlement agreements;

 
The continued evolution of the Company’s business model from an operating entity with research and development, manufacturing and limited selling capabilities to a holder of intellectual property which might have commercial application to other interested parties;

 
The lack of adequate capital which precludes the Company from supporting next-stage obligations associated with its current product license for Imagent, wherein it acts as the licensor, and which has therefore disrupted the prospective nature of this commercialization activity with the licensee and which may therefore require an adjustment to the future business arrangements between the parties, which currently is being explored but has not concluded. See Note 14; and

 
The uncertainty about obtaining additional capital in amounts adequate to provide for the continued protection of the Company’s patent portfolio associated with the Purchased Technology, notwithstanding the two technology cross-licenses entered into in the fourth quarter 2004 and the third quarter 2005, respectively and the license agreement amendment finalized in the fourth quarter of 2006.

In light of these factors, discussed in greater detail in Note 13, the Company determined that as of December 31, 2005, the carrying values of the Purchased Technology and the related deferred royalties asset and the deferred revenue, should be reduced to their estimated fair values and the amount of the write-down recognized as additional “Impairment losses.”
 
Accordingly the net carrying value of the Purchased Technology was written down to $1,000,000 and the related deferred royalties asset and deferred revenue were written down to $-0- at December 31, 2005.
 
At December 31, 2006, the Company concluded, after further evaluation and taking into consideration a) the amended and restated license agreement with Kyosei, for which the Company received gross proceeds of $1,200,000 earned license revenue in November and December 2006 and b) the likelihood of entering into any similar transactions in the near term, that the remaining $1,000,000 Purchased Technology should be written down to $-0-, and a charge of the same amount was recorded as an additional and final impairment loss on Purchased Technology for the year ended December 31, 2006.
 
The financial statements do not include any additional adjustments to reflect the possible future effects on the recoverability and classification of assets or the amount and classification of liabilities that may result from the outcome of any remaining uncertainties.
 
46

 
Recapitalization and Merger - In May 1997, IMCOR Pharmaceutical Co. (formerly known as Photogen Technologies, Inc. which was then known as M T Financial Group, Inc. (“M T Financial”)), acquired Photogen, Inc. through a subsidiary merger. As a result, Photogen, Inc. became a wholly-owned subsidiary of M T Financial and then M T Financial changed its name to Photogen Technologies, Inc. (then subsequently on February 5, 2005 to IMCOR Pharmaceutical, Co.).
 
Principles of Consolidation - The accompanying consolidated financial statements include the accounts of IMCOR Pharmaceutical Co. and its wholly owned subsidiary, Sentigen Ltd. (“Sentigen”), a Bermuda entity. Sentigen was a joint venture with Elan International, Ltd. which was formed in October 1999 with the Company as an 80.1% owner. Elan was a 19.9% owner but retained substantive participation and management rights. On June 10, 2004, the joint venture was terminated and Sentigen became a wholly owned subsidiary of the Company. The Company’s investment in Sentigen was accounted for under the equity method from inception through June 10, 2004 and consolidated thereafter. All inter-company transactions have been eliminated. Sentigen currently has no operations and it is likely that it will be dissolved by the Bermuda authorities.
 
Stock Splits - On March 4, 2005, the Company effected a 1-for-20 reverse stock split of its common stock. In November 2002, the Company effected a 1-for-4 reverse stock split of its common stock. All share and per share amounts related to common stock in the consolidated financial statements have been retroactively adjusted for all periods presented to give effect to these reverse stock splits.
 
Use of Estimates - The preparation of financial statements in conformity with accounting principles generally accepted in the United States of America requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and the disclosure of contingent assets and liabilities at the date of the financial statements, as well as the reported amounts of revenue and expenses during the reporting period.  Actual results could differ materially from the estimates and assumptions that the Company uses in the preparation of its financial statements.
 
Cash Equivalents - Highly liquid investments with a maturity of three months or less when purchased are classified as cash equivalents. Cash equivalents are carried at cost, which approximate their fair market value.
 
Concentration Risk - The Company maintains its cash in bank deposit accounts which, at times, may exceed federally insured limits. The Company has not experienced any losses in such accounts and believes it is not exposed to significant concentration risk based on the quality of the financial institutions where deposits are maintained. Cash balances held by federally insured institutions at December 31, 2006 which exceed federally insured limits amount to $1,212,935.
 
Property, Plant and Equipment - Property, plant and equipment were originally stated at cost.  Depreciation and amortization of equipment and furniture and fixtures was provided for using the straight-line method over the estimated useful lives of the assets, generally three to seven years.  Leasehold improvements are being amortized on a straight-line basis over the lives of the respective leases or the service lives of the improvements, whichever is shorter. Expense for maintenance and repairs are expensed as incurred. Impairment in the carrying values of these respective assets has been charged to “Impairment losses.” Upon disposition, all associated property, plant and equipment asset costs, together with the related accumulated depreciation and amortization and allowance for valuation impairment for the respective assets have been written off, and to the extent that such net carrying values exceeded the amount of the disposition proceeds received, if any, such difference is then charged to “Loss on sale of equipment.”
 
47

 
Long-Lived Assets - The Company reviews the carrying values of its long-lived assets for possible impairment whenever an event or change in circumstances indicates that the carrying value of these assets may not be recoverable and recognizes a loss in the form of an allowance for valuation impairment when it is probable that the estimated future cash flows will be less than the carrying value of the asset. Any long-lived assets held for disposal are reported at the lower of their carrying amounts or fair value less cost to sell.
 
Intangible Assets and Deferred Royalties - Intangible assets are amortized on a straight-line basis over their estimated useful lives. Deferred royalties assets are amortized over the same period as the related deferred revenue to which these assets relate. The carrying values of intangible assets are periodically reviewed and impairments, if any, are recognized when the expected future benefit to be derived from an intangible asset is less than its carrying value. Upon disposition, all associated intangible asset and deferred royalties asset costs, together with the related accumulated amortization and allowance for valuation impairment for the respective assets are written off, and to the extent that such net carrying values exceeded the amount of the disposition proceeds received, if any, such difference is then additionally recognized.
 
Research and Development - Research and development costs are charged to expense when incurred.
 
Revenue Recognition and Deferred Revenue - Prior to December 31, 2005, the date by which the Company had ceased production, operating and sales activities associated with its Imagent Purchased Technology and had sold off all of its other technology assets, the Company recognized revenue arising from previously received payments related to product and technology cross-license agreements ratably over remaining useful life (10-12 years) of the related technology as calculated from that time forward the respective licensing payments were received. At December 31, 2005, the Company recognized the then remaining deferred revenue as a reduction of “Impairment losses” related to the corresponding impairment write downs on intangible assets and deferred royalties made on a contemporaneous basis. Commencing in the year ending December 31, 2006, receipts for fees related to product and technology license agreements for which there are no future performance obligations are recognized when the Company has the contractual rights to receive the funds. See Notes 6, 13 and 14.
 
Income Taxes - Deferred tax liabilities and assets are provided for differences between the book and tax bases of existing assets and liabilities and tax loss carryforwards and credits using tax rates expected to be in effect in the years in which differences are expected to reverse. Valuation allowances are provided to the extent realization of tax assets is not considered likely.
 
48

 
Basic and Diluted Loss Per Common Share - Basic and diluted loss per common share is computed based on the weighted average number of common shares outstanding. Loss per share excludes the impact of outstanding options, warrants and convertible preferred stock as they are anti-dilutive. Potential common shares excluded from the calculation at each of the years ended December 31, are as follows:
 
 
 
2005
 
2006
 
Options pursuant to plans
   
167,017
   
110,671
 
Options outside of plans, net of cashless component
   
34,977
   
34,977
 
Warrants
   
819,736
   
819,736
 
Issuable upon conversion of preferred stock
   
833,334
   
833,334
 
Total
   
1,855,064
   
1,798,718
 
 
Fair Value of Financial Instruments - The carrying amounts reported in the consolidated balance sheets for cash, accounts payable and accrued expenses approximate fair value because of the short-term nature of these amounts. The carrying value of unsecured notes payable approximates its fair value, as interest approximates market rates.
 
Gain on Extinguishment of Debt - Reductions of amounts owed obtained through debt settlement arrangements with creditors are recorded as gains from extinguishment of debt in the period such arrangements are reached.
 
Stock Options - Effective January 1, 2006, the Company adopted the provisions of FASB Statement No. 123(R), “Share-Based Payments,” (“SFAS 123(R)”) which establishes the accounting for employee stock-based awards. Under the provisions of SFAS No.123(R), stock-based compensation is measured at the grant date, based on the calculated fair value of the award, and is recognized as an expense over the requisite employee service period (generally the vesting period of the grant). The Company adopted SFAS No. 123(R) using the modified prospective method and, as a result, periods prior to January 1, 2006 have not been restated.
 
Recent Accounting Pronouncements:
 
In March 2006, the FASB issued Statement No. 156, “Accounting for Servicing of Financial Assets, an amendment of FASB Statement No. 140” (“SFAS No. 156”). SFAS No. 156 amends SFAS No. 140 to require that all separately recognized servicing assets and liabilities in accordance with SFAS No. 140 be initially measured at fair value, if practicable. Furthermore, this standard permits, but does not require, fair value measurement for separately recognized servicing assets and liabilities in subsequent reporting periods. SFAS No. 156 is also effective for the Company beginning January 1, 2007; however, the standard is not expected to have any impact on the Company’s financial position, results of operation or cash flows.
 
In June 2006, the FASB issued Interpretation No. 48, “Accounting for Uncertainty in Income Taxes - an interpretation of FASB Statement No. 109,” (“FIN 48”). FIN 48 clarifies the accounting for uncertainty in tax positions and requires that a Company recognize in its financial statements the impact of a tax position, if that position is more likely than not of being sustained on audit, based on the technical merits of the position. The provisions of FIN 48 are effective for fiscal years beginning after December 15, 2006. The adoption of FIN 48 is not expected to have any impact on the Company’s financial statements.
 
49

 
In September 2006, the FASB issued Statement No. 157, “Fair Value Measurements” (“SFAS No. 157”). SFAS 157 defines fair value, establishes a framework for measuring far value in generally accepted accounting principles and expands related disclosures about fair value measurements. This Statement focuses on creating consistency and comparability in fair value measurements. SFAS No. 157 is effective for the Company beginning January 1, 2008, including any interim reporting periods. The Company is currently evaluating the impact of adopting SFAS No. 157 on its financial statements.
 
In September 2006, the SEC Staff issued Staff Accounting Bulletin No. 108 (“SAB 108”) to require registrants to quantify financial statement misstatements that have been accumulating in their financial statements for years and to correct them, if material, without restating. Under the provisions of SAB 108, financial statement misstatements are to be quantified and evaluated for materiality using both balance sheet and income statement approaches. SAB 108 is effective for fiscal years ending after November 15, 2006. The adoption of SAB 108 did not have a material impact on our financial statements.
 
Reclassification - Certain reclassifications have been made to the prior years’ financial statements to conform to the current year presentation. These reclassifications had no effect on previously reported results of operations or retained earnings.
 
3. Acquisition of Imagent Business:
 
On June 18, 2003, the Company acquired the medical imaging business from Alliance Pharmaceutical Corp. (“Alliance”), pursuant to an Asset Purchase Agreement dated June 10, 2003 (the “Alliance Asset Purchase Agreement”). The acquisition costs and allocation to the assets acquired and liabilities assumed were as follows:
 
Total consideration and acquisition costs:        
Fair value of common stock issued in 2003
 
$
5,583,268
 
Fair value of common stock issued in 2004
   
5,043,226
 
Prior cash advances from Company
   
4,018,052
 
Cash paid at closing
   
669,117
 
Current year payments to vendors on behalf of Alliance
   
388,387
 
Notes payable assumed
   
2,500,000
 
Obligation to pay Alliance creditors
   
3,421,891
 
Acquisition costs
   
1,254,205
 
 
 
$
22,878,146
 
 
     
Fair value of assets acquired:
     
Leasehold improvements
 
$
5,527,738
 
Equipment
   
1,712,262
 
 
   
7,240,000
 
Purchased technology
   
15,638,146
 
 
 
$
22,878,146
 

The fair value of the common stock issued in 2003 and 2004 were all based on the fair value of the shares of stock on June 18, 2003, which was the date the shares were issuable. The Alliance Asset Purchase Agreement provided that the Company was obligated to pay Alliance creditors up to a specified amount for various categories of creditors. During 2004, some obligations to Alliance creditors were satisfied for less than the amounts originally estimated and as a result, the Company reduced both accrued expenses and the original acquisition cost of the leasehold improvements by $240,000.
 
50

 
Prior to reaching a settlement agreement with Alliance dated September 19, 2005 in conjunction with the settlement of certain litigation (see Note 8) (the “Alliance Settlement”), the Company was obligated to pay Alliance under the Alliance Asset Purchase Agreement contingent consideration (“Earnout”) based on revenues from the sale of Imagent from June 18, 2003 through June 18, 2010, subject to certain reductions. The Earnout was to be based on varying percentages applied to the revenue during the twelve month periods ending on each anniversary date as follows: 7.5% of revenue up to $20,000,000; 10% of revenue from $20,000,001 up to $30,000,000; 15% of revenue from $30,000,001 up to $40,000,000; and 20% of revenue in excess of $40,000,000. The Earnout was to have been reduced by the net amounts the Company was obligated to pay pursuant to a license agreement with Schering Aktiengesellschaft (“Schering AG”) and any amounts that may be due from Alliance pursuant to an indemnification agreement. The Earnout was subject to three additional offsets that were to have been applied in different priorities but in total may have provided reductions to the Earnout obligation up to approximately $7,000,000. Due to the absence of any meaningful current or expected revenue from Imagent, management was not previously able to, and therefore did not include the present value of future estimated Earnout payments in the determination of the consideration paid for the acquisition. Future Earnout obligations under the original arrangement would have therefore have been expensed in the periods when they could have been reasonably estimated.
 
As noted above, the Company entered into the Alliance Settlement on September 19, 2005, pursuant to which (i) each party’s respective ongoing obligations to one another under the Alliance Asset Purchase Agreement were terminated, including any obligations related to Earnout and Future Earnout, (ii) each party granted the other a mutual general release (which resolved, among other things, the parties’ claims against one another for various accumulated post-closing payments), and (iii) the parties agreed to share in the proceeds of future transactions involving the disposition of the Company’s Imagent asset in accordance with the following schedule:

Proceeds
 
Alliance Percentage
 
Company Percentage
$1 to $1,450,000
 
10.0%, not to exceed $100,000
 
90.0% of first $1,000,000;
100.0% of next $450,000
$1,450,001 to $5,000,000
 
30.0%
 
70.0%
$5,000,001 and above
 
33.3%
 
66.7%
 
The purchase costs allocated to intangible assets related to the acquisition of the Purchased Technology were estimated by management based on the fair value of the assets acquired. Purchased Technology has been amortized on a straight-line basis over the estimated remaining life of twelve years up to and through December 31, 2005, at which date it was written down to a carrying value of $1,000,000. This remaining value of $1,000,000 was further reduced to a carrying value of $-0- at December 31, 2006.  Purchased Technology is stated at cost, less accumulated amortization and allowance for impairment. See Note 6.
 
51

 
4. Investment in and Advances to Affiliate
 
On October 7, 1999, Sentigen, Ltd. (“Sentigen”) was formed as a joint venture between the Company and Elan International Services, Ltd. (“Elan”) to develop and commercialize nanoparticulate diagnostic imaging agents for the detection and treatment of cancer through lymphography.
 
On June 10, 2004, the Company and Elan terminated the joint venture. As a result, on that date Sentigen became a wholly owned subsidiary of the Company and was consolidated in the Company’s financial statements, with a carrying value of $735,916, whose value was wholly related to a worldwide license to certain patented Elan technology.
 
Through that date the Company had recognized “Loss from joint venture” totaling $14,518,000, primarily as a result of the amortization on the underlying license and impairment charges which had been taken from time to time, based on Sentigen’s period assessments of the future cash flows or valuation of the fair value of the license.
 
By December 31, 2005 this resulting license asset had been sold to a third party - see Note 6.
 
 5. Property, Plant and Equipment
 
 As a result of restructuring activities began by the Company during 2005 (See Note 13), all previously recorded property, plant and equipment had been either sold or written down to a $0 carrying value by December 31, 2005.
 
Depreciation and amortization expense on property, plant and equipment was $593,901 in 2005 at the time the assets were taken out of service pursuant to the Company’s restructuring activities commenced during the second quarter of 2005 and $-0- in 2006. See Note 13. In addition an impairment allowance reserve was established in 2005 totaling $3,265,492, of which $3,072,315 was attributed to leasehold improvements and $193,177 was attributed to furniture, fixtures and equipment.
 
During the year ended December 31, 2005, furniture, fixtures and equipment with a net book value of $550,689 ($1,827,859 cost, less $1,083,993 accumulated depreciation and amortization and less $193,177 allowance for impairment reserve)] was sold or otherwise disposed of for $324,384 in net proceeds, resulting in a loss on disposal of equipment totaling $226,305.
 
On July 19, 2005, and as part of its continued restructuring activities, the Company concluded two concurrent, interdependent negotiations with EOP-Industrial Portfolio, LLC (“EOP”), its lessor of the Company’s leased facilities property located at 6175 Lusk Boulevard in San Diego, California, and a new tenant for this property. See Note 8 for additional discussion. As a result of these negotiations, the Company executed a lease termination agreement, involving among other things, a surrender of the facility and the underlying leasehold improvements with a net book value of $20,000 ($5,287,738 cost, less $2,195,423 accumulated amortization and less $3,072,315 allowance for impairment reserve). Concurrent with that transaction and pursuant to an agreement with the new tenant, the Company received $20,000 from the new tenant, resulting in no gain or loss in the leasehold improvements, other than to the extent of the previously recorded impairment allowance noted above.
 
52

 
6. Intangible Assets and Deferred Royalties:
 
The cost and accumulated amortization of intangible assets and deferred royalties as of each of the years ended December 31, are as follows:

 
 
2005
 
2006
 
Purchased technology:
         
Cost
 
$
15,638,146
 
$
15,638,146
 
Less allowance for valuation impairment
   
(11,373,572
)
 
(12,373,572
)
Accumulated amortization
   
(3,264,574
)
 
(3,264,574
)
 
 
$
1,000,000
 
$
 
Patents:
           
Cost
 
$
500,000
 
$
500,000
 
Less allowance for valuation impairment
   
(274,479
)
 
(274,479
)
Accumulated amortization
   
(225,521
)
 
(225,521
)
 
  $
 
$
 
             
Deferred royalties:
           
Cost
 
$
500,000
 
$
500,000
 
Less allowance for valuation impairment
   
(416,666
)
 
(416,666
)
Accumulated amortization
   
(83,334
)
 
(83,334
)
 
  $
 
$
 

During 2005 the Company, as part of its restructuring activities (see Note 13), entered into an agreement in principal with a third party to sell its technology license asset for $102,500, net of certain costs, and an impairment allowance of $570,321 was then recorded, resulting in a net carrying cost of $102,500 ($735,916 cost, less $63,095 accumulated amortization and less $570,321 allowance for impairment reserve). During the quarter ending September 30, 2005 the agreement was finalized, and the Company received the contemplated $102,500, resulting in no further gain or loss on the sale of this technology license asset, other than to the extent of the previously recorded impairment allowance noted above.
 
The carrying values of the Purchased Technology were amortized on a straight-line basis over their estimated useful lives ranging from 10-12 years through December 31, 2005. The deferred royalties asset was amortized into operations over the same period as the related deferred revenues associated from a product license agreement to which these assets relate, which is 12 years, also through December 31, 2005. However, in light of the additional considerations addressed by the Company associated with its continuing restructuring activities (See Notes 2 and 13), management determined at December 31, 2005 that impairment allowances for the Purchased Technology and the deferred royalties assets, amounting to $11,373,572 and $416,666, respectively were appropriate, and the necessary adjustments were recorded. At December 31, 2006 management made a subsequent adjustment of further and final impairment allowance for the remaining $1,000,000, related to the Purchased Technology. This determination was made after giving consideration to a) the conclusion of the amended and restated license agreement with Kyosei, for which the Company received $1,200,000 in earned license revenues and b) the likelihood of any similar agreements which might be reached in the near term.
 
53

 
Amortization expense for purchased technology, patents and technology license was $1,326,766 in and $-0- in 2005 and 2006, respectively. There is no additional amortization contemplated in the next five years, as the only remaining intangible asset held by the Company, the Purchased Technology, has no current carrying value at December 31, 2006, even though it continues to be held in the event that the Company might reach one or more alternative transactions which may result in net cash payments to the Company (none of which is predicted in the near term).
 
7. Accrued Expenses and Assumed Acquisition Obligations:
 
 
 
December 31,
 
December 31,
 
 
 
2005
 
2006
 
Assumed acquisition obligations
 
$
924,784
 
$
924,784
 
Accrued payroll, deferred bonuses and related expenses
   
512,656
   
512,656
 
Accrued legal fees
   
139,153
   
139,153
 
Accrued interest
   
121,568
   
218,755
 
Other accrued expenses
   
190,000
   
190,000
 
 
 
$
1,888,161
 
$
1,985,348
 

During 2005, the Company reduced its “Assumed acquisition obligations” by $200,000 as a result of reaching overall settlements in litigation and other disputes involving the Purchased Technology. See Note 8. The remainder of the “Assumed acquisition obligations” relates primarily to past due payment obligations owed to several parties totaling $622,750 at December 31, 2005 and 2006.
 
During 2005 the Company also paid out $353,884 in salary-related costs which had been accrued at December 31, 2004 in “Accrued payroll, deferred bonuses and related expenses,” including $156,172 in accrued salary, $159,787 in earned vacation and $37,925 in the remainder of a severance obligation for a former employee. There were no further payments of salary related costs made in 2006.
 
During 2005, the former CEO’s employment with the Company was terminated, and the Company recorded a reserve for severance totaling $275,000. This individual is also owed $206,250 for a bonus earned in 2004. No portion of these obligations, totaling $481,250, has been paid; such amounts are included in “Accrued payroll, deferred bonuses and related expenses” at both December 31, 2005 and 2006.
 
One of the Company’s law firms had originally agreed to accept shares of the Company’s common stock for a portion of their services rendered during the six months ending June 30, 2005. However, prior to the end of this period, the law firm advised the Company that it preferred to be compensated for these services in cash payment, to the extent the Company is ultimately able to pay. The Company agreed to this request and has accordingly recorded this obligation, totaling $139,153, to “Accrued legal fees” at both December 31, 2005 and 2006.
 
Incurred but unpaid interest totaling $218,755, which represents an increase of $97,187 from December 31, 2005 to December 31, 2006, is included in “Accrued interest,” and is associated with various interest-bearing obligations, including “Notes payable unsecured” ($192,233), “Accrued royalty fees” owed to Schering AG ($431,946) and various payable obligations associated with the “Assumed acquisition obligations” referenced above ($622,750). 
 
54

 
Incurred but unpaid Board fees, including related fees for service on various committees, totaling $180,000, and which were incurred during the period January 1 to December 31, 2005 ($101,000) are included in “Other accrued expenses.” No additional Board fees were accrued during the period January 1 to December 31, 2006. There have been no payments for any such obligations incurred after the first quarter ending March 31, 2004.
 
8. Commitments and Contingencies
 
Leases: The Company previously leased its facilities and certain equipment under non-cancelable operating leases, which expired at various times through 2008. The facilities leases required the Company to pay for all maintenance, insurance and property taxes.
 
As more completely discussed in Note 13, the Company was released from the remainder of its building lease obligations related to future minimum rental payments totaling $2,244,113 pursuant to a lease termination agreement executed July 19, 2005 and made effective on or about July 31, 2005.
 
The Company had two other lease obligations for rental equipment, but at the time of vacating its former facilities, the Company made this equipment available back to the respective lessors, and believes it has no further financial obligations beyond that which was incurred in 2005 totaling approximately $123,000.
 
Commencing approximately August 1, 2005, the Company rented temporary office space, originally for a minimum of 3 months, but then converting this arrangement to month-to-month by year end. Total expense incurred under this arrangement totaled $12,654 for the remainder of the year ended December 31, 2005 and $5,018 for the year ended December 31, 2006.
 
Total rental expense charged to operations for the years ended December 31, 2005 was approximately $583,000. In addition to the rental expense, the charges from the landlord at 6175 Lusk Boulevard in San Diego, California for maintenance, insurance and property taxes totaled approximately $93,000 in 2005.
 
License Agreements: As part of the acquisition of the Imagent business from Alliance in June 2003, the Company assumed a license agreement between Alliance and Schering AG (“Schering AG License”) which provides the Company with exclusive marketing and manufacturing rights, drug compositions, and medical devices and systems related to perfluorocarbon ultrasound imaging products, including Imagent, in the United States, for a five-year period from the date of the first commercial sale of a related product, which was August 2003. Schering AG is entitled to royalty payments based on five percent of sales revenues ($4,871 earned through December 31, 2006) and ten percent of license fee revenues that are received as lump sum payments ($4,871 and $530,000, respectively, earned through December 31, 2006). Only $102,950 of such royalties have been paid as of December 31, 2006.
 
If at the expiration of the five-year period the Company has not provided royalty payments to Schering AG in excess of $20,000,000 then Schering AG has the option to become a co-promoter of products, in which event the Company will be entitled to receive royalty payments from Schering AG. It is unlikely that the Company can meet this minimum royalty threshold obligation.
 
55

 
The Company entered into an amended and restated license agreement with Kyosei effective as of November 13, 2006. Under the terms of the revised agreement the Company has been relieved of its obligation under the original agreement to manufacture and supply Imagent for Kyosei and Kyosei was assigned certain patents and a trademark for use in Japan. Kyosei paid a total fee of $1,300,000. In accordance with the terms of the Settlement Agreement between the company and Alliance dated as of September 19, 2005 an aggregate of $100,000 (approximately $91,000 net, after deducting Alliance’s allocated share of direct expenses) of the consideration due from Kyosei was paid to Alliance. In addition, after taking into account direct expenditures attributed to this transaction for which the company had remaining responsibility, and which totaled approximately $104,000 (including agent commission fees and incremental royalty obligations to Schering AG), the company received net approximately $1,096,000
 
Litigation: On June 18, 2003, the Company, together with Alliance, the prior owner of the Purchased Technology, filed a complaint against Amersham Health, Inc. and two other Amersham affiliates (now known as GE Healthcare Ltd.) (collectively “Amersham”) alleging that certain Amersham products infringed on claims in the patents covering Imagent. The complaint alleged that principally through the Optison® product, Amersham infringed on eight patents owned by the Company. The Company further alleged misappropriation of trade secrets as well as other state law claims against Amersham.
 
The Company entered a Settlement Agreement and License (the “Amersham Settlement”) dated as of September 19, 2005 with Amersham, Alliance and Molecular Biosystems, Inc., at which time the parties dismissed their litigation and granted each other fully paid-up, irrevocable, royalty-free, non-exclusive cross-licenses, with the right to sub-license, and mutual releases. The Amersham Settlement resolved the parties’ claims arising under the case described above. See Notes 13 and 14 for a discussion of the financial terms of these settlements.
 
On May 11, 2005, the Company was served with an unlawful detainer lawsuit by EOP, the lessor of the property located at 6175 Lusk Boulevard in San Diego, California, regarding the Company’s default on its building lease for failing to pay back rent. As described more in Notes 8 and 13, as part of the Company’s restructuring activities commenced in the second quarter ended June 30, 2005, the Company was allowed to peacefully vacate the premises by July 31, 2005 pursuant to a lease termination agreement. The Company was further released from all past due rents, late payment fees and any future lease payments for which the base rents totaled at least $2,244,000.
 
The Company is not now a party to any litigation.
 
9. Notes Payable:
 
Notes Payable - Unsecured:
 
The unsecured notes payable bear interest at eight percent annually.
 
56

 
One of the Company’s directors is a general partner in the two entities that are owed $192,233 as of both December 31, 2005 and 2006.
 
10. Shareholders’ Equity (Deficit) and Mezzanine Equity:
 
  (a)  Series A Preferred Stock - In October 2004, the Company authorized and issued 4,500 shares of Series A Convertible Preferred Stock (“Series A-New”) to Bristol-Meyers Squibb Medical Imaging, Inc. (“BMSMI”) for $4,500,000 in conjunction with a non-exclusive technology cross-licensing agreement whereby BMSMI also paid the Company $4,000,000. Each share of the Series A-New is entitled to a liquidation preference of $1,000 per share and is convertible into 833,334 shares of the Company’s common stock at an effective conversion rate of $5.40 per common share. The Company may force the conversion of these shares into common stock after October 2005 in the event that the value of the Company’s common stock exceeds $8.10 for ten consecutive days. This mandatory conversion feature is limited to converting into an amount of common shares which does not exceed 19.9 percent of the then outstanding shares of the Company’s common stock.
 
An investment banking firm was paid a $680,000 fee and issued warrants expiring in October 2009 to purchase 66,667 shares of the Company’s common stock at $5.40 per share. The Company estimated $60,400 value for the warrants using the Black-Scholes pricing model. These costs were allocated pro rata between the value of the cross-licensing agreement and the value of the Series A-New shares. Accordingly, $392,000 was charged to shareholders’ equity as a reduction of the proceeds from the Series A-New shares and $348,400 was charged to expense.
 
  (b) Common Stock - As of December 31, 2004, the Company was subject to four groups of registration rights agreements. In the aggregate, these agreements cover approximately 5,553,969 shares of common stock (including approximately 735,881 shares issuable upon the exercise of warrants and 833,334 shares issuable upon the conversion of the Series A Convertible Preferred Stock) and require the Company to register those shares under various terms and subject to specific conditions in the agreements. In accordance with the terms of certain of these registration rights agreements, on January 11, 2005 a registration statement became effective relating to the resale of 2,332,679 shares of common stock including 735,881 shares issuable upon the exercise of warrants. In addition, on February 8, 2005 the Company filed a registration statement relating to the resale of 2,448,467 shares of common stock.
 
All of the shares issued in January through April 2005 were subject to pending registration statements which are not currently effective. The effectiveness of the registration statements was delayed while the Company responded to the SEC’s various comments which arose during the comment process. Given the Company’s current financial circumstances and its goal to maximize the funds available to its creditors, its board of directors has determined that the Company will not continue to pursue its efforts to effect its registration statements that were on file with the SEC (File Nos. 333-122625 and 333-117907). Those registration statements will be withdrawn.
 
The Company has stopped accruing penalty shares for the security holders who received shares subject to that certain registration rights agreement dated as of April 14, 2004 because without an effective registration statement the Company is unable to abide by the contractual requirement that the penalty shares such parties receive freely tradable shares.  In addition, we entered into an agreement with Oxford Bioscience Partners IV L.P., MRNA Fund II, L.P., and Mi3 L.P. to cease accruing penalty shares as of June 30, 2005.   In general, privately issued shares held by investors for more than one year may be sold under Rule 144.
 
57

 
Many of the Company’s investors have held their shares in the Company for more than a year and will be qualified to sell their shares under Rule 144, subject to the restrictions set forth therein; indeed, several such investors have sold shares utilizing Rule 144. However, given the Company’s current financial situation, at some point in 2006 or thereafter the Company may elect to cease reporting under the Exchange Act, and as a result, investors will no longer be eligible to resell their shares of the Company’s common stock under Rule 144 (unless the shares have been held for two years, in which case they would be freely saleable under Rule 144(k)).
 
On March 13, 1998, the Company completed a private placement of 10,938 shares of common stock for $640 per share to a number of accredited investors.  The Company received $6,950,000, net of related expenses of approximately $50,000 from this offering.
 
On February 9, 2001, the Company’s shelf registration on Form S-3 was declared effective.  Under the shelf registration, the Company could have issued up to $40,000,000 of common stock.  As of December 31, 2002, 8,694 shares had been issued under the shelf registration for cash proceeds of $1,068,723, net of related expenses of $56,252.  The Company’s registration statement is no longer effective.
 
As of April 2, 2001, the Company no longer met the eligibility requirements to continue selling shares under the S-3.  Prior to realizing it was ineligible to continue using the S-3, the Company sold 6,231 shares of common stock for $650,000.  Through June 2003, this amount had been reclassified from permanent equity to mezzanine equity as the Company could be required to repay a portion of this amount to the purchaser.  In the second quarter of 2003 the Company recognized in permanent equity the issuance of these shares.
 
On November 12, 2002, the Company completed a private placement of 416,667 shares of common stock for $21.60 per share to a number of accredited investors.  The Company received proceeds of $8,677,000, net of related expenses of $387,000.  Proceeds included cash of $6,113,000 and the conversion of a credit facility with an entity controlled by a then director of the Company with borrowings of $2,500,000 which converted into 115,741 shares of common stock.
 
In December 2002, the Company completed a second closing of the November 12, 2002 private placement in which 140,227 shares of common stock were sold for $21.60 per share for gross proceeds of $3,028,902.
 
On November 12, 2002, the Company effected the split-off of Photogen, Inc. and the assets and liabilities related to the Company’s therapeutic line of business to the five founding stockholders of the Company (the “Tennessee Stockholders”) in exchange for all of their common stock in the Company.  The Tennessee Stockholders owned 256,855 shares of the Company and those shares were cancelled prior to December 31, 2002.  The market value of the 256,855 shares on the date of the split-off was $12,226,319.
 
58

 
Pursuant to a Standstill and Make Whole Agreement dated as of December 30, 2002 with Xmark Fund L.P. and Xmark Fund, Ltd. (collectively “Xmark”), secured creditors of Alliance, the Company issued a total of 37,500 shares to Xmark in January through March 2003.  Xmark agreed to not exercise any rights against Alliance as a creditor.  The value of these shares was treated as an expense at fair market value amounting to $1,173,750.
 
On May 2, 2003, the Company executed a Going Forward Agreement with Xmark that provided, among other things, for the issuance of shares of the Company’s common stock upon the acquisition of the Purchased Technology as payment for interest owed by Alliance to Xmark.  On June 18, 2003, the Company issued 109,907 shares of its common stock to certain creditors of Alliance, including 52,807 shares to Xmark pursuant to the Going Forward Agreement, as partial consideration for the Technology Purchase.  Following approval by shareholders, the Company would issue an additional approximately 99,276 shares to certain other creditors as part of the Purchased Technology.  The value of these shares was treated as acquisition consideration at fair market value (see Note 3).  Such approval was obtained at the Company’s shareholder meeting held on February 5, 2004.
 
On May 27, 2003 the Company issued 563 shares of its Common Stock to Xmark as a penalty for failure to timely register certain shares held by Xmark. The value of these shares was treated as an expense at fair market value amounting to $25,200.
 
On July 31, 2003 the Company issued 4,149 shares of its Common Stock to Xmark for interest and penalties, including the failure to timely register certain shares of its Common Stock held by Xmark as of that date.  The value of these shares was treated as an expense at fair market value amounting to $158,987.
 
On September 2, 2003, pursuant to a Letter Agreement dated as of August 18, 2003 with Xmark, the Company issued 1,312 shares of its Common Stock to Xmark for the failure to timely register certain shares of its Common Stock held by Xmark as of that date.  The value of these shares was treated as an expense at fair market value amounting to $28,085.
 
Total shares issued to Xmark as a result of the agreements noted above was 96,331.  In addition, an aggregate of 2,152 shares of the Company’s Common Stock were issuable to Xmark for payment of accrued interest.  Xmark had a put right for all these shares that, under certain circumstances, would have required the Company to purchase the shares from Xmark at a price of $20.00 per share.  As a result, $1,969,668 was classified as mezzanine equity at December 31, 2003.
 
During 2003, in addition to the above issuances, the Company issued an aggregate of 7,005 shares pursuant to several factors including cash, compensation for service and cashless exercise of stock options.
 
In February 2004 the Company received $46,690 from Xmark as proceeds from the sale of unregistered shares in excess of their original purchase price.
 
On March 5, 2004, the Company issued 102,699 shares of the Company’s common stock to certain creditors of Alliance. Of the total shares issued, 99,276 shares (valued at $5,043,226) related to the acquisition consideration for the Imagent Business which had been classified as Common Stock to be Issued at December 31, 2003.
 
59

 
During the six months ended June 30, 2004, Xmark sold 15,732 shares of common stock for which it held a put right. In June 2004, the Company entered into an agreement with Xmark whereby the Company exchanged all remaining 80,600 puttable shares held by Xmark plus related obligations and fees for an aggregate of $2,128,447 of Secured Notes that were payable on or before December 1, 2004.
 
On April 19 and June 30, 2004, the Company sold 1,268,750 shares of its common stock for $8.00 per share and 735,875 warrants exercisable for $10.00 per share (including 101,500 warrants issued to its two placement agents), for approximately $10.15 million. The net proceeds to the Company were approximately $9,325,000. In addition, holders of an aggregate of approximately $12,719,500 principal amount of the Company’s Secured Promissory Notes and Revolving Convertible Senior Secured Promissory Notes (“Notes”), plus $713,884 interest accrued and added to the note balance, converted these Notes into 1,687,034 shares of the Company’s common stock at $8.00 per share, 7,861 of which were returned prior to year-end 2004 due to an over-issuance associated with an interest computation adjustment.
 
In June 2004, the Company issued 30,829 shares of its common stock as a partial settlement of obligations under an equipment lease (See Note 13). As part of the terms of the settlement, the Company remains obligated to make an additional payment equal to the difference (if any) between the net proceeds the lessor receives from sales of these shares of stock during the 12 months after the Company registers the shares and $468,601 (which represents the number of issued shares valued at $15.20 per share). Accordingly, the Company has recorded into equity only that portion of the issued shares’ par value, or $617. The balance of $467,984 is included in the balance of Accrued Equipment Lease Obligation in the balance sheet at December 31, 2004.
 
During 2004, the Company issued 11,563 shares of common stock to consultants for services rendered and to be rendered. The value of these shares was $43,688 of which $10,500 is presented as Unearned Stock Compensation.
 
During 2004, the Company recorded $1,221,613 for penalties and fees, representing 327,957 shares of common stock due to shareholders for late registration of their shares. In June 2004, the Company extinguished its obligation for $203,190 (8,323 shares) of penalties and fees, which included $70,239 accrued as of December 31, 2003, as part of the exchange of Xmark puttable shares, noted previously. In December 2004, the Company issued 8,935 shares related to $244,469 of penalties and fees. As of December 31, 2004, the balance of shares to be issued which could be quantified included (a) 316,462 shares related to penalties and late registration fees totaling $812,000 and (b) 818 shares related to penalties and late registration fees totaling $18,587. In addition, an additional $20,300 in penalties and late registration fees were accrued but for which the number of shares to be issued could not be quantified as of December 31, 2004.
 
On January 11, 2005, 328,053 common shares were issued in settlement of penalties and late registration fees totaling $893,200, including those 316,462 shares which were quantifiable at December 31, 2004. Accordingly, $832,300 was reclassified from common stock to be issued, the additional $60,900 was charged off to current 2005 year operations, and the combined amounts totaling $893,200 were recorded to common stock and additional paid in capital in 2005.
 
60

 
On February 8, 2005, the remainder 818 shares which were quantifiable at December 31, 2004 were issued and the corresponding value of $18,587 was reclassified from common stock to be issued to common stock and additional paid in capital.
 
During 2004 one of the Company’s law firms agreed to accept shares of the Company’s common stock for services rendered. As of December 31, 2004, 101,378 shares are issuable related to $247,865 of services, which were expensed.
 
During 2004 two of the Company’s consultants agreed to accept shares of the Company’s common stock for services rendered. As of December 31, 2004, 4,232 shares are issuable related to $22,000 of services, which were expensed. These shares were subsequently issued on February 8, 2005 and accordingly $22,000 was reclassified from common stock to be issued to common stock and additional paid in capital at that time.
 
On February 10, 2005, in final settlement of further and all claims from a former employee, the Company modified exiting options for 1,875 shares to make them effectively exercisable in 21,125 net shares at an exercise price equal to zero. At December 31, 2004, the $42,250 cost associated with this contemplated transaction was accrued into operations. Upon completing the agreement in 2005, the associated accrued expense was reclassified into additional paid in capital.
 
During 2005 the Company issued an additional 2,526,872 common shares to settle $1,607,693 of penalties and late registration fees, associated with registration obligations relating to 1,679,173 common shares issued in 2004 upon the conversion of debt and accumulated interest totaling $13,433,384. 2,008,913 of these common shares were issuable at June 30, 2005, and have been accordingly included in the Company’s weighted average computations of weighted common shares outstanding for the year ending December 31, 2005. The common shares to settle these penalties and late registration fees were issued as follows: (a) 63,810 common shares on February 8, 2005, (b) 454,149 common shares on April 11, 2005, and (c) 2,008,913 common shares on December 30, 2005.
 
During 2005 the Company recorded into expense $10,500 related to previously issued shares which had been recorded to unearned compensation.
 
On January 24, 2005, the Company amended it Articles of Incorporation to increase the number of common shares authorized from 150,000,000 to 200,000,000. 
 
61

 
11. Stock Incentive Plans, Options and Warrants
 
The Company maintains three long-term incentive compensation plans (“Plans”) as follows:
 
The 1998 Long-Term Incentive Compensation Plan, which provides for the granting of up to 25,000 stock options to key employees, directors and consultants (57 of which have been exercised to date); 421 options were outstanding as of December 31, 2006.
 
The 2000 Long-Term Incentive Compensation Plan, which provides for the granting of up to 1,500,000 stock options to key employees, directors and consultants (none of which have been exercised to date); 110,250 options were outstanding as of December 31, 2006.
 
The 2000 Senior Executive Long-Term Incentive Compensation Plan, which provides for the granting of up to 50,000 stock options to senior executives (none of which have been exercised to date). Options exercised under this plan contain certain registration rights; no options were outstanding as of December 31, 2006.
 
Options granted under these Plans may be either “incentive stock options” within the meaning of Section 422A of the Internal Revenue Code, or nonqualified options. The stock options are exercisable over a period determined by the Board of Directors (through its Compensation Committee), but generally no longer than 10 years after the date they are granted.
 
The following summarizes the activity under the Plans combined for each of the years ended December 31,:
 
 
 
2005
 
2006
 
Options outstanding at beginning of year
   
516,670
   
167,017
 
Options granted
   
95,000
   
 
Exercised
   
   
 
Options forfeited
   
(444,653
)
 
(56,346
)
Options outstanding at end of year
   
167,017
   
110,671
 
 
           
Option prices per share granted
 
$
8.00
 
$
n/a
 
 
           
Weighted average exercise price:
           
Options granted
 
$
8.00
 
$
 
Options granted at less than market price
 
$
 
$
 
Options granted at the market price
 
$
8.00
 
$
 
Options forfeited
 
$
123.20
 
$
184.79
 
Options outstanding at end of year
 
$
70.49
 
$
12.29
 
Options exercisable at end of year
 
$
97.80
 
$
15.67
 
Number of shares exercisable
   
116,267
   
61,921
 
Aggregate Intrinsic Value
 
$
 
$
 
 
62

 
A summary of the status of the Company’s nonvested shares as of December 31, 2006, and changes during the year ended December 31, 2006, is presented below:
 
Nonvested Shares
 
Shares
 
Weighted-Average
Grant Date
Fair Value
 
Nonvested at January 1, 2005
   
50,750
 
$
1.79
 
Granted
   
   
 
Vested
   
(2,000
)
$
4.61
 
Forfeited
   
   
 
Nonvested at December 31, 2006
   
48,750
 
$
1.68
 
 
As of December 31, 2006, there was $19,011 of total unrecognized compensation cost related to nonvested share-based compensation arrangements granted under the Plan. That cost is expected to be recognized over a weighted average period of 11.6 months.
 
In addition to the options issued as part of the Plans summarized above, in 2002, the Company issued fully vested options outside of the plans that, after amendment in 2003, expire in February 2010. 1,875 of these options were exercisable at $84 per share and the balance of the options were effectively exercisable into 13,852 shares of the Company’s stock at an exercise price equal to zero, of which 500 were exercised in 2003 (the exercise price for these “cashless” options was originally $25.40 per share). These options were issued in settlement of claims from a former employee and were fully expensed in 2002. On February 10, 2005, in final settlement of further and all claims, the Company modified the options for the 1,875 shares to make them effectively exercisable into 21,125 shares at an exercise price equal to zero.
 
The following table summarizes information related to outstanding and exercisable options of the Plans as of December 31, 2006:
 
 
 
Options Outstanding
 
Options Exercisable
 

Range of
Exercise Price
 

Number of
Shares
 

Weighted
Average
Exercise
Price
 
Weighted
Average
Remaining
Contractual
Life in Years
 

Number of
Shares
 

Weighted
Average
Exercise
Price
 
$2.80 - $18.40
   
103,000
 
$
7.85
   
8.13
   
54,250
 
$
7.71
 
$18.41 - $21.60
   
500
 
$
18.60
   
6.01
   
500
 
$
18.60
 
$21.61- $91.20
   
6,813
 
$
41.71
   
6.34
   
6,813
 
$
41.71
 
$91.21 - $220.00
   
45
 
$
220.00
   
3.92
   
45
 
$
220.00
 
$220.01 - $550.00
   
88
 
$
550.00
   
3.70
   
88
 
$
550.00
 
$550.0 1- $1060.00
   
225
 
$
890
   
1.68
   
225
 
$
890.00
 
Total
   
110,671
 
$
12.29
   
7.99
   
61,921
 
$
15.67
 

During the year ended December 31, 2006, the Company recognized stock-based compensation of $41,943 pursuant to SFAS No.123(R) in the “Selling, general and administrative” line item of the Consolidated Statement of Operations. Additionally, no modifications were made to outstanding stock options prior to the adoption of SFAS No. 123(R), and no cumulative adjustments were recorded in the Company’s financial statements.
 
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Prior to January 1, 2006, the Company accounted for stock-based compensation in accordance with provisions of Accounting Principles Board Opinion No. 25, “Accounting for Stock Issued to Employees,” (“APB No. 25”) and related interpretations. Under APB No. 25, compensation cost was recognized based on the difference, if any, on the date of grant between the fair value of the Company’s stock and the amount an employee must pay to acquire the stock. In certain cases the Company granted stock options at an exercise price less than the market price on the date of grant, and accordingly compensation expense was recognized for the stock option grants in periods prior to the adoption of SFAS No. 123(R).
 
SFAS No. 123(R) requires disclosure of pro-forma information for periods prior to the adoption. The pro-forma disclosures are based on the fair value of awards at the grant date, amortized to expense over the service period. The Company has computed the pro forma disclosures required by SFAS No. 123, “Accounting for Stock-Based Compensation,” for options granted using the Black-Scholes option-pricing model prescribed by SFAS No. 123. The assumptions used and weighted-average information are as follows for each of the years ended December 31,:

 
 
2005
 
2006
 
Weighted-average fair value of options granted
 
$
1.60
 
$
n/a
 
Expected dividend yield
 
$
 
$
n/a
 
Risk-free interest rate at grant date
   
3.44
%
 
n/a
 
Expected stock price volatility
   
233.16
%
 
n/a
 
Expected option lives (years)
   
5
   
n/a
 
 
The following table illustrates the effect on net income and earnings per share as if the Company had applied the fair value recognition provisions of SFAS No. 123, “Accounting for Stock-Based Compensation,” for the period ending December 31, 2005 prior to the adoption of SFAS No. 123(R), and the actual effect on net income and earnings per share for the period after the adoption of SFAS No. 123(R).
 
 
 
2005
 
2006
 
Applicable to common stockholders:
         
Net loss, as reported
 
$
(17,697,883
)
$
(349,816
)
Add stock based compensation expense
             
included in reported net loss
   
1,077,780
   
41,943
 
Less total stock-based employee
           
compensation expense determined under
           
the fair-value based method for all awards
   
(3,478,149
)
 
(41,943
)
Pro forma net loss
 
$
(20,098,252
)
$
(349,816
)
Net loss per common share (basic and diluted):
             
Reported
 
$
(2.95
)
$
(0.05
)
Pro forma
 
$
(3.35
)
$
(0.05
)
 
64

 
The following summarizes the activity related to warrants for each of the years ended December 31:

 
 
2005
 
2006
 
Warrants outstanding at beginning of year
   
820,147
   
819,736
 
Warrants granted
   
   
 
Warrants exercised
   
   
 
Warrants forfeited
   
(411
)
 
 
Warrants outstanding at end of year
   
819,736
   
819,736
 
Weighted average exercise price:
           
Warrants granted
 
$
 
$
 
Warrants exercised
 
$
 
$
 
Warrants forfeited
 
$
955.60
 
$
 
Warrants outstanding at end of year
 
$
10.40
 
$
10.40
 
Warrants exercisable at end of year
 
$
10.03
 
$
10.03
 
Number of shares exercisable
   
812,136
   
812,136
 
 
The following table summarizes information related to outstanding and exercisable warrants as of December 31, 2006:

 
 
Warrants Outstanding
 
Warrants Exercisable
 

Range of
Exercise Price
 

Number of
Shares
 

Weighted
Average
Exercise
Price
 
Weighted
Average
Remaining
Contractual
Life in Years
 

Number of
Shares
 

Weighted
Average
Exercise
Price
 
$5.40 - $5.40
   
66,667
 
$
5.40
   
2.80
   
66,667
 
$
5.40
 
$10.00 - $10.00
   
735,881
 
$
10.00
   
2.50
   
735,881
 
$
10.00
 
$21.60 - $50.40
   
17,000
 
$
37.69
   
0.90
   
9,400
 
$
27.42
 
$884.54 - $884.54
   
188
 
$
884.54
   
3.10
   
188
 
$
884.54
 
Total
   
819,736
 
$
10.40
   
2.49
   
812,136
 
$
10.03
 
 
12. Dividends
 
There were no dividends for the years ended December 31, 2005 and December 31, 2006.
 
13. Restructuring Activities
 
On August 31, 2003, the Company closed its Pennsylvania corporate headquarters and transferred its headquarters to its facility in San Diego, California. The lease for the corporate headquarters expired in July 2004. As of December 31, 2003, the Company had accrued $236,700 as the estimate of the amount due for the remaining lease obligation. The Company subsequently determined that the landlord had leased its vacated premises and as a result the Company has reduced the estimate of the remaining lease obligation during 2004, and which is included in accounts payable at December 31, 2005 at $99,764.
 
The Company had an operating lease for laboratory equipment which expired during 2004. During 2001, the Company determined that equipment leased by the Company under this operating lease would no longer be used by the Company in its research and discontinued making the monthly lease payments. In 2001 the Company recorded a provision for the remaining future lease payments of $1,264,208. At December 31, 2003 the balance of this obligation was $719,940. In June 2004, the Company reached a settlement with the equipment lessor issuing 30,829 shares of common stock and paying $75,000 with an agreement to pay $25,000 in January 2005. The settlement requires the Company to make additional payments to the lessor to the extent the lessor’s proceeds from its future sales of this stock are below $468,601 (30,829 shares at a guaranteed minimum price of $15.20 per common share). This contingent obligation is classified in the balance sheet at both December 31, 2004 and 2005 as $467,984 accrued equipment lease obligation, with the remainder as $31 par value common stock and $586 additional paid in capital (attributed to the minor difference effected upon recording the change in the underlying shares issued upon the retroactive restatement related to the 1-for-20 reverse stock split - see Note 10). In addition, the scheduled January 2005 payment, which has not been made, is also included in accrued equipment lease obligation at both December 31, 2005 and 2006. The balance of the estimated obligation in June 2004 in excess of the value of the settlement was recorded as miscellaneous income ($126,257).
 
65

 
In April 2005, the Company, after assessing its cash resources, circumstances related to the continued patent litigation matter (see Note 8) and inability to obtain additional sources of cash necessary to continue the Company’s planned business activities, formulated and began to adopt a new restructuring plan which initially included a reduction-in-force of a majority of the full-time employees and part-time employees or consultants who perform administrative support, manufacturing and related functions. In addition, a limited number of full-time employees were transferred to part-time positions to assist the Company with the actions necessary to curtail its operations. The Company also temporarily suspended its manufacturing operations at that time, pending further developments.
 
The Company’s board of directors later concluded that, for a variety of factors, including some of which are cited in Note 2, it was not probable that the Company would obtain additional cash funds to continue operating even on a limited basis in the near term. Therefore, during May 2005, the Company modified its restructuring plan to include the disposition of its furniture, fixtures and equipment, to vacate its premises, and other steps to effect an orderly cessation or suspension of operations other than those necessary to facilitate completion of the restructuring plan.
 
The Company incurred approximately $34,000 in cash disbursements for severance pay associated with this restructuring plan during the year ended December 31, 2005, and also paid approximately $191,000 in previously accrued vacation obligations, primarily to terminated employees (which is required under California employment laws). The Company also terminated its vacation benefit program, and vacation was no longer accrued for then remaining employees. In addition, the Company negotiated two cash retention bonuses totaling $80,000 with two employees deemed integral to the restructuring efforts of the Company as part of this restructuring plan; however, one of the employees, as consideration, also waived any further claim he had to a previously earned, accrued but unpaid bonus of $60,000 from 2003. Accordingly, the Company recognized on a net basis only $20,000 bonus expense in the quarter ended June 30, 2005. The retention bonus obligations were paid as follows: $30,000 during the quarter ended June 30, 2005, $35,000 during the quarter ended September 30, 2005 and the remainder of $15,000, owed to one individual and accrued as of September 30, 2005, was subsequently paid in November 2005. All efforts required of these two individuals were largely concluded by September 30, 2005.
 
66

 
As part of the employee reduction plan, the employment of the Company’s CEO and President was terminated effective May 31, 2005. A reserve for severance (equal to one year’s salary, as required by this individual’s employment contract), amounting to $275,000, was recorded as expense during the quarter ending June 30, 2005, but remains unpaid and is accordingly included in accrued expenses at December 31, 2006.
 
As also discussed in Note 8, the Company concluded a successful negotiation with EOP, the lessor of the Company’s facility at 6175 Lusk Boulevard, San Diego, California. In conformity with the terms of this agreement, the Company vacated the premises on or about July 31, 2005 and surrendered its lease security deposit totaling $297,000. The Company was released from all other obligations, including past due rents totaling approximately $331,292 at July 31, 2005 (approximately $248,469 at June 30, 2005), as well as late payment fees and any future lease payments, commitments and/or contingencies. Future minimum lease payments at June 30, 2005 eliminated as result of the lease termination agreement totaled $2,244,113 at that date. In addition, Alliance, which was the lease guarantor, was also released from any and all claims, commitments and contingencies.
 
As a result of the successful adoption of the plan to vacate the premises, the Company recorded a leasehold valuation impairment allowance of approximately $3,072,000 in the quarter ending June 30, 2005, leaving a net carrying value of leasehold improvements as of June 30, 2005 totaling $20,000.
 
On June 16, 2005, the Company sold the majority of its excess equipment at a public auction, which netted the Company $270,820, $175,000 of which was received by June 30, 2005. The balance of $95,820 was recorded as accounts receivable on that date, and was subsequently received during the quarter ended September 30, 2005. At June 30, 2005 the Company recorded an equipment valuation impairment allowance of approximately $193,000, leaving a net carrying value of $31,220 for unsold equipment remaining as of that date.
 
The remainder of the Company’s equipment and leasehold interest was subsequently sold subsequent to June 30, 2005 for $51,220 and, accordingly, all carrying values of related assets, accumulated depreciation and amortization, and valuation impairment allowances have been adjusted to $-0- as of December 31, 2005.
 
In addition to the impairment losses charged to operations, the Company recognized $248,599 as a “Loss on sale of equipment” as of June 30, 2005 for those certain asset sales which were concluded by that date; however, the Company has since collected $1,500 in miscellaneous collections attributed to assets whose book value had previously been written off, and also collected a net payment of $20,794 from its property and liability insurance carrier as a result of a submitted claim for stolen property which occurred during the period the Company was vacating the premise in favor of the new tenant. As a result, the actual “Loss on sale of equipment” has been reduced to $226,305 at December 31, 2005.
 
67

 
During the quarter ending June 30, 2005, the Company solicited interest from several parties regarding its technology license asset, which relates to the Company’s N1177 compound and PH-50, the same or substantially same compound for a different indication. An agreement in principle was reached with a party to acquire these related assets for $102,500, net of third party intermediary compensation costs. Accordingly, the Company recorded a technology license valuation impairment allowance of approximately $570,000 in the quarter ending June 30, 2005, leaving a net carrying value of technology license as of June 30, 2005 of $102,500.
 
During the quarter ended September 30, 2005, the Company and the third party completed the asset purchase agreement for the sale of the Company’s assets exclusively related to N1177 and PH-50. The sale includes certain patent rights related to N1177 and PH-50 and other intellectual property, including the Company’s technology license asset. The agreement called for an aggregate purchase price (net of a third party intermediary fee, of $102,500) which was due in two payments, the first of which was $71,500 and was paid at closing and the balance of $31,000 was paid prior to year end upon satisfactory conclusion of certain required follow-on activities. Accordingly, all carrying values of this technology license related to its cost, accumulated amortization and valuation allowance have been adjusted to zero as of December 31, 2005.
 
The Company entered into the Amersham Settlement dated as of September 19, 2005 with Amersham, Alliance and Molecular Biosystems, Inc. The Amersham Settlement resolved the parties’ claims arising under the case described above. Under the terms of the Amersham Settlement, the Company’s technology cross-license was valued at $1,200,000 in favor of the Company, for which the Company received $1,000,000 directly from Amersham. The balance, or $200,000, was paid directly by Amersham to Alliance which served as the cash consideration to Alliance under the separate but concurrent Alliance Settlement discussed below. The parties dismissed their litigation and granted each other fully paid-up, irrevocable, royalty-free, non-exclusive cross-licenses, with the right to sublicense, and mutual releases.
 
In addition, the Company entered into the Alliance Settlement with Alliance dated as of September 19, 2005 pursuant to which: (i) each party’s respective ongoing obligations to one another under the Asset Purchase Agreement dated June 10, 2003 between the Company and Alliance were terminated, (ii) each party granted the other a mutual general release (which resolved, among other things, the parties’ claims against one another for various accumulated post-closing payments), and (iii) the parties agreed to share in the proceeds of future transactions involving the disposition of the Company’s Imagent asset.
 
When the Purchased Technology was initially acquired in June 2003, the Company not only acquired the underlying technology of the FDA approved product Imagent, but ongoing operation which held out the possibility at the time that the Company could generate at least two strategic sources of revenue: (a) from direct product sales and (b) from product licensing and/or technology cross-licensing activities. For those reasons, the accounting policy was then established that the value of the Purchased Technology should be amortized on a straight-line basis into expense over the estimated useful remaining life of the underlying intellectual property, including the patent estate, which was 12 years from the date of the acquisition.
 
68

 
Notwithstanding the difficulties associated with the ongoing litigation with Amersham, the Company nevertheless has been able to execute to a significant extent on the second part of the strategic revenue plan through 2005), that of obtaining cash-based revenues from product licensing and/or technology cross-licensing activities, including:
 
·  
$4,000,000 paid by Kyosei Pharmaceutical Co., Ltd. (“Kyosei”), a unit of the Sakai Group in Japan, in December 2003 and April 2004 pursuant to a product license, which was potentially worth as much as $10,000,000 to the Company if the future milestone obligations could be met;
 
·  
$4,000,000 paid by BMSMI in October 2004 for a technology cross-license; and
 
·  
$1,200,000 paid by Amersham in September 2005 for a technology cross-license, pursuant to reaching the Amersham Settlement and the related Alliance Settlement.
 
Because the Purchased Technology and the follow-on transactions for the above-described strategic revenues collected through September 2005, as well as the derivative royalties obligation owed to Schering AG pursuant to the Kyosei product license agreement, were inextricably related to one another, the accounting policies had initially been implemented with the primary objective being to match the recognition of license/cross-license revenue and royalties expense to the amortization of the Purchased Technology. Therefore, up to December 31, 2005, the related license fees and royalties were deferred and only partially recognized on a straight-line basis into license revenue and royalties expense, based on schedules which commence on the dates the respective transactions were concluded, and over the remaining estimated useful lives of the underlying technology.
 
Furthermore, because the Company could not predict during the initial stages of its restructuring activities, particularly in light of the then ongoing negotiations with Amersham and Alliance, it was not possible to project what additional arrangements might be made with potential business partners for Imagent, financial or otherwise. As a result, the Company was unable estimate potential changes to the fair market value of the Purchased Technology, together with the related deferred royalties asset and deferred revenue credits carried on the Company’s balance sheet at December 31, 2005.
 
However, the Company’s management determined at December 31 2005, after the Amersham and Alliance negotiations had been concluded and agreements executed, that the amount of carrying value of the Imagent assets could more readily be assessed, based on the reduced uncertainty associated with the previously described matters and an estimate of potential license fees related to a possible adjustment of the Kyosei agreement, for which negotiations were underway but could not be disclosed with any specificity at that date. Based on all factors then available, the Imagent asset was written down to its then-estimated fair value of $1,000,000 through the establishment of an allowance for valuation impairment. At the same time, the Company accordingly also concluded that the remaining deferred revenues and related deferred royalties assets, should be recognized at that date, rather than amortized into future operations, due to the lack of adequate capital and a full-time staff, which make it impracticable to continue normal operating activities.
 
The Kyosei product license agreement contemplated certain ongoing collaborative activities between the Company and Kyosei, enabling the Company to achieve future payments upon the fulfillment of prospective performance obligations by each party, but there is no ongoing performance obligation as such related to prior amounts received. The two technology cross-license agreements with BMSMI and Amersham likewise do not contemplate any future performance obligations in the furtherance of the respective agreements.
 
69

 
The Company entered into an amended and restated license agreement with Kyosei effective as of November 13, 2006. Under the terms of the revised agreement the Company has been relieved of its obligation under the original agreement to manufacture and supply Imagent for Kyosei and assigned Kyosei certain patents and a trademark for use in Japan. Kyosei paid a total fee of $1,300,000. In accordance with the terms of the Settlement Agreement between the Company and Alliance dated as of September 19, 2005 an aggregate of $100,000 (approximately $91,000 net, after deducting Alliance’s allocated share of direct expenses) of the consideration due from Kyosei was paid to Alliance. In addition, after taking into account direct expenditures attributed to this transaction for which the Company had remaining responsibility, and which totaled approximately $104,000 (including agent commission fees and incremental royalty obligations to Schering AG), the company received net approximately $1,096,000.
 
An additional assessment of the remaining carrying value of the Imagent Purchased Technology of $1,000,000 was made at December 31, 2006, and in light of all relevant factors available to management, a final write-off of this remaining carrying value was recorded as an additional charge to “impairment losses” as of that date.
 
As the Company’s 2005 restructuring activities continued during the balance of 2005 and into 2006, the efforts have continually focused on seeking additional alternatives as to how best maximize the value in the Company’s significant remaining asset the Purchased Technology, while at the same time minimizing and eliminating additional significant contingent claims, including those which might have been made had the Company not been able to negotiate to satisfactory conclusions matters related to (a) the ongoing patent litigation, (b) the related disputes with Alliance and (c) the facilities lease termination.
 
The Company continues to evaluate its alternatives with respect to efforts to sell or otherwise maximize asset values related to the Purchased Technology, for the benefit of its creditors and shareholders, and will continue to consider as alternatives the sale or license of its remaining assets, a merger or other material transaction. Such a transaction may include selling the Purchased Technology, a license or sale of the patent portfolio underlying the Purchased Technology, a manufacturing rights agreement, or another form of transaction. To date, efforts to fashion additional arrangements have yielded only preliminary results; however, the Company continues to explore transactional possibilities with potentially interested parties. Although there remains some potential for a sale, license, development agreement or comparable transaction, no such transaction appears likely for the near term as of December 31, 2006.
 
The Company also faces certain continuing challenges to preserve and optimize the value of its Purchased Technology for the benefits of creditors and shareholders, not the least of which is the current lack of a full-time staff and reduced financial resources. For example, without an immediate capability to manufacturing the Imagent product, the Company can no longer support the prospective aspects of the Kyosei product license agreement as was originally executed, therefore putting out of practical reach any portion of the future potential payments totaling $6 million which might have otherwise flowed from this contract. In addition, it is similarly unlikely that the Company could readily restart the production of Imagent without first commencing a lengthy and costly process to reestablish manufacturing capabilities, which also puts out of reach for the time being the additional possibility of Imagent product sales. Continued protection of the value of the Company’s patent portfolio may represent another potential source of revenues for the Company, if factors warrant and the underlying cost-benefit analysis supports such action(s). And while the Company’s history of enforcing its rights in patents indicates that there is merit in this approach, patent protection, enforcement and/or possible litigation activities can be costly, time consuming and the results are inherently uncertain, so there can be no assurance that this business strategy will result in net benefits to the Company.
 
70

 
As a result of those adjustments and other asset impairment transactions described elsewhere in these “Notes to Consolidated Financial Statements,” the Company has recorded net impairment losses for each of the years ending December 31, 2005 and 2006 as summarized below:

 
 
2005
 
2006
 
Impairment losses:
         
Purchased Technology write down
 
$
11,373,572
 
$
1,000,000
 
Add recognition of remaining deferred royalties
   
416,666
   
 
Less recognition of remaining deferred revenues
   
(8,119,485
)
 
 
Net impairment attributed to Purchased Technology and related deferred license revenues and royalties
   
3,670,753
   
1,000,000
 
Patents
   
   
 
Technology license
   
570,321
   
 
Leasehold improvement
   
3,072,315
   
 
Furniture, fixtures and equipment
   
193,177
   
 
 
 
$
7,506,566
 
$
1,000,000
 

The Company’s subsidiary, Sentigen, Ltd., a Bermuda entity, currently has no operations. It is likely to be administratively dissolved by the Bermuda authorities.
 
14. Deferred Revenue:
 
In December 2003, the Company entered into a product license agreement with Kyosei for the development and marketing of Imagent in Japan for all radiology and cardiology indications. Terms of the agreement call for the payment to the Company of up to $10,000,000 in fees and development milestone payments plus royalties on commercial sales. Kyosei will also pay the Company to manufacture Imagent for Kyosei’s clinical and commercial requirements. The Company received gross payments of $2,000,000 each in December 2003 and April 2004. These milestone payments have been amortized into income through December 31, 2005 over the remaining life of the related patents at the time each payment is received, which was approximately 12 years. The Company has recognized cumulative license revenue related to this agreement totaling $633,333, including $338,095 for 2005, prior to considering the additional adjustment made in accordance with the Purchased Technology valuation assessment more fully discussed in Note 13.
 
On October 29, 2004, the Company received $4,000,000 related to the cross-licensing provisions of a technology cross-licensing and securities purchase agreement with Bristol-Meyers Squibb Medical Imaging, Inc. (“BMSMI”) covering ultrasound contrast agent patents. The agreement provides both BMSMI and the Company the right to further develop and commercialize their respective ultrasound contrast imaging agents without risk of infringing upon the other company’s patent rights. This payment has been amortized into income through December 31, 2005 over the remaining life of the related patents, which was approximately 11 years at the time of the agreement. The Company has recognized cumulative license revenue related to this agreement totaling $417,914, including $358,212 for 2005, prior to considering the additional adjustment made in accordance with the Purchased Technology valuation assessment more fully discussed in Note 13.
 
71

 
On September 19, 2005 the Company entered into a Settlement Agreement and License with Amersham, Alliance and Molecular Biosystems, Inc. The Amersham Settlement resolved the parties’ claims arising under the litigation - see Note 8. Under the terms of the Amersham Settlement, the Company received a technology cross-license which was valued at $1,200,000 in favor of the Company, for which the Company received $1,000,000 directly from Amersham. The balance, or $200,000, was paid directly by Amersham to Alliance which served as the cash consideration to Alliance under the separate but concurrent Alliance Settlement more fully discussed in Note 3. The parties dismissed their litigation and granted each other fully paid-up, irrevocable, royalty-free, non-exclusive cross-licenses, with the right to sub-license, and mutual releases.
 
The Company recorded $1,200,000 attributed to the Amersham technology cross-license to deferred revenue, which it then began to amortize into income through December 31, 2005 over the remaining life of the related patents, which was approximately 10¼ years at the time of the agreement. The Company recognized cumulative license revenue related to this agreement totaling $29,268, all of which is attributable to 2005, prior to considering the additional adjustment made in accordance with the Purchased Technology valuation assessment more fully discussed in Note 13.
 
As more fully discussed in Note 13, the Company recognized the balance of the deferred revenue at December 31, 2005, totaling $8,119,485 ($3,366,667 related to the original Kyosei product license, $3,582,086 related to the BMSMI technology cross-license and $1,170,732 related to the Amersham technology cross-license), taken into operations as a reduction of “Impairment losses” recorded in connection with its restructuring activities.
 
15. Gain on Extinguishment of Debt
 
Beginning in December 2005, the Company began to negotiate with certain creditors who were willing to settle and provide a full release of claims against the Company, in exchange for significantly discounted payments. During the years ended December 31, 2005 and 2006, the Company paid $10,360 and $36,321, respectively, to settle claims totaling $114,802 and $361,242, respectively. This resulted in the Company recognizing gains on extinguishment of debt in the amounts of $104,442 and $324,921, respectively.
 
72

 
16. Income Taxes
 
As of December 31, 2005 and 2006, the Company has net operating loss (“NOL”) carryforwards for federal income tax purposes of approximately $41,701,000 and $42,052,000, respectively, that expire from 2023 through 2026, and $35,599,000 and $35,950,000, respectively, for California state income tax purposes that expire in 2013, 2014, 2015 and 2016. The Tax Reform Act of 1996 contains provisions that may limit the utilization of NOL carryforwards available to be used in any given year in the event of significant changes in ownership interests as defined in the act. Management has provided a valuation allowance in the amount of $27,493,000 as of December 31, 2006 due to the uncertainty of the future realization of the deferred tax asset. The net change in valuation allowance for 2006 was a decrease of $2,328,000.
 
The expected income tax provision, computed based on the Company’s pre-tax income and the statutory Federal income tax rate, is reconciled to the actual tax provision reflected in the accompanying consolidated financial statements as follows:

 
 
2005
 
2006
 
Expected federal income tax benefit
 
$
(6,017,000
)
$
(119,000
)
Expected state income tax benefit, net of federal benefit
   
(1,033,000
)
 
(20,000
)
Increase in valuation allowance
   
6,622,000
   
(2,328,000
)
Losses for which no benefit recognized
   
429,000
   
17,000
 
Other
   
(1,000
)
 
 
Change in estimate
   
   
2,450,000
 
Provision for income tax expense
 
$
 
$
 
 
The following is a schedule of the significant components of the Company’s net deferred tax assets as of each of the years ended December 31,:
 
 
 
2005
 
2006
 
Net operating loss carryforwards
 
$
19,607,000
 
$
16,395,000
 
Deferred revenue
   
   
 
Amortization of intangible assets
   
242,000
   
(139,000
)
Impairment in asset valuations
   
4,640,000
   
5,038,000
 
Equity in loss of affiliate
   
5,081,000
   
5,799,000
 
Other temporary timing differences
   
251,000
   
400,000
 
Deferred tax asset
   
29,821,000
   
27,493,000
 
Less valuation allowance
   
(29,821,000
)
 
(27,493,000
)
 
  $
 
$
 
 
73


ITEM 8. CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING AND FINANCIAL DISCLOSURE.
 
None.
 
ITEM 8A. CONTROLS AND PROCEDURES.
 
In September 2004, our management concluded that there were certain reportable conditions and material weaknesses in our internal controls and procedures. As noted in our Annual Report on Form 10-KSB for the year ended December 31, 2004, as amended, we had taken steps and had started to implement remediation procedures to address the identified reportable conditions and material weaknesses. However, based on our limited capital resources and the adoption of a restructuring plan in April 2005, which included a reduction-in-force of our full-time employees and part-time employees or consultants who perform administrative support, manufacturing and related functions, we have been unable to complete the previously identified remediation plans. As a result, certain of the previously identified reportable conditions and material weaknesses, particularly those related to the small size of our accounting staff and the limited number of our financial and accounting personnel, still exist.
 
 Although certain material weaknesses in internal controls and procedures previously disclosed have not been fully remediated, we believe that changes and procedures that were implemented and remain in place, mitigate and reduce the likelihood of material misstatements or improper disclosures in our financial statements and reports. These changes and procedures include (i) engaging of Larry D. Grant as a financial consultant, (ii) adding Darlene Deptula-Hicks to our Audit Committee, (iii) requiring the Executive Committee of the Board to ratify routine and/or recurring expenditures and approve significant commitments and non-routine expenditures and payments, (iv) requiring both Larry D. Grant and our other senior executives to review and approve the incurrence of all significant obligations and remittance of payments, (v) adopting separate Codes of Ethics for all employees and for senior executives and finance personnel, (vi) adopting or updating the charters of our Audit and Compensation Committees, and (vii) creating a Disclosure Committee and adopting a Disclosure Committee Charter. In addition, the cessation of operations and discharge of employees simplifies the complexity and reduces the number of transactions we must monitor, thereby significantly simplifying the internal control process.
 
 Our senior executive officers have previously consulted with Larry D. Grant and have participated in the evaluation of our disclosure controls (as defined in Rules 13a-15(e) and 15d-15(e) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”)) required by paragraph (b) of Rule 13a-15 or Rule 15d-15, as of December 31, 2006 and, based on that evaluation, concluded that due to insufficient staff our disclosure controls and procedures were not fully effective to ensure timely collection, evaluation and disclosure of information relating to the Company that would potentially be subject to disclosure under the Exchange Act, and the rules and regulations thereunder. However, to the extent corrections and improvements in internal controls and disclosure controls and procedures cannot be implemented and/or maintained, management believes appropriate oversight and review is currently in place in light of the minimal transactions conducted during this fiscal year to prevent material misstatements in our annual financial reporting. 
 
74

 
ITEM 8B. OTHER INFORMATION.
 
None.
 
ITEM 9. DIRECTORS, EXECUTIVE OFFICERS, PROMOTERS, CONTROL PERSONS AND CORPORATE GOVERNANCE; COMPLIANCE WITH SECTION 16(A) OF THE EXCHANGE ACT.
 
Directors. The table below sets forth our seven directors and information concerning their age and position with the company as of March 31, 2006. Except for Mr. Fleming (who is a director of Memory Pharmaceuticals Corp.) and Ms. Deptula-Hicks (who is a director of Technest Holdings Inc.), none of these individuals is a director of any other company subject to the reporting requirements under the federal securities laws.
 
Name
 
Age
 
Position
Brian M. Gallagher, Ph.D.(1)
 
59
 
Director, Chairman of the Board
Taffy J. Williams, Ph.D.(1)
 
57
 
Director
Robert A. Ashley(2)
 
49
 
Director
Richard T. Dean, Ph.D.(2)(3)
 
59
 
Director
Darlene M. Deptula-Hicks, M.B.A.(2)
 
49
 
Director
Jonathan J. Fleming(1)(3)
 
49
 
Director
Alan D. Watson, Ph.D., M.B.A.(3)
 
54
 
Director
 
(1) Member of the Executive Committee 
 
(2) Member of the Audit Committee
 
(3) Member of the Compensation Committee
 
Ms. Deptula-Hicks is the Chairperson of our Audit Committee. Our Board has determined that she is an “audit committee financial expert” and is “independent” as contemplated by SEC rules.
 
 Each director of the company holds office until the next annual meeting of stockholders and until his or her successor has been elected and qualified. Each executive officer holds office at the pleasure of the Board of Directors and until his or her successor has been elected and qualified. A brief discussion of the business experience of each director is set forth below.
 
Brian M. Gallagher, Ph.D. is Chairman of the Board and has served as a director since July 22, 2004. Dr. Gallagher received his B.S. is biology from St. Louis University, his M.S. in marine sciences from Long Island University, and his Ph.D. in biology from St. John’s University. Dr. Gallagher currently serves as a Chief Executive Officer of Magen Biosciences. He previously served as a Director of CollaGenex Pharmaceuticals, Inc. and ImaRx Therapeutics, Inc., a privately held, drug delivery/specialty pharmaceutical company with a focus on cardiovascular diseases. From 1994 to 2003, he was the Chairman, President and Chief Executive Officer of CollaGenex Pharmaceuticals, Inc.
 
75

 
Taffy J. Williams, Ph.D. served as our President, Chief Executive Officer and a director between May 17, 2000 and May 31, 2005, when his employment as our President and CEO terminated as part of our employee reduction plan. Prior to joining the company, Dr. Williams served as CEO and President of PANAX Pharmaceuticals for two and half years and President of InKine Pharmaceuticals for two years. He received his Bachelor of Science in Chemistry from the University of Notre Dame and his Ph.D. in Chemistry from the University of South Carolina.
 
Robert A. Ashley began serving as a director following his election at the annual stockholders’ meeting held on January 20, 2005. Mr. Ashley received his MA in Biochemistry from St. Peter’s College, Oxford University. He is currently the chief executive officer of Ashley BioPharm. From 2004 until March 2007, he served as President, Chief Executive Officer and Chairman of the Board of Amplimed Corporation. From 1994 to 2003, he served in various capacities with CollaGenex Pharmaceuticals Inc., including as Senior Vice President, Vice President of Commercial Development and Managing Director of CollaGenex International Ltd.
 
Richard T. Dean, Ph.D. has served as a director since October 27, 2003. Dr. Dean received his B.S. from Cornell University, his M.S. from the University of Michigan and his Ph.D. from the University of California at Berkeley. Since 2004, Dr. Dean has served as the Chief Executive Officer of Xanthus Life Sciences, Inc., a company founded to develop novel oncology drugs. From 1999 to 2003, Dr. Dean served in various capacities with Schering AG, including as Head of Strategic Business Development, Diagnostics and Radiopharmaceuticals. Dr. Dean has over 25 years experience in the pharmaceutical and biotechnology field.
 
Darlene M. Deptula-Hicks, M.B.A. has served as a director since July 22, 2004. Ms. Deptula-Hicks received her B.S. in accounting from New Hampshire College and her M.B.A. from Rivier College. She is currently the Executive Vice President of Finance and Chief Financial Office of iCAD Inc., a provider of computer-aided detection products for cancer detection and a Director of Technest Holding, Inc., a public defense and homeland security company. From 2002 until 2006, she served as Executive Vice President and Chief Financial Officer of ONI Medical Systems, Inc. Prior to that, she was the Executive Vice President, Chief Financial Officer and Treasurer of Implant Sciences Corporation from 1998 to 2001. Ms. Deptula-Hicks has over 20 years of experience in financial management positions, primarily in the life sciences sector.
 
Jonathan J. Fleming has served as a director since August 15, 2003. Mr. Fleming has been a Partner of Oxford Bioscience Partners since 1996 and its Managing Partner since 2001. Oxford Bioscience Partners is an international venture capital firm with committed capital of more than $800 million specializing in life science technology based investments. Mr. Fleming holds a Master’s degree in Public Administration from Princeton University and a Bachelor of Arts degree from the University of California, Berkeley. Mr. Fleming is a co-founder and is Chairman of the Board of Memory Pharmaceuticals. He is also Chairman of the Board of BioProcessors Corporation and Dynogen Corporation, and is a director of several private companies, including Leerink Swann. Mr. Fleming is a Trustee of the Museum of Science in Boston and is a Senior Lecturer at MIT’s Sloan School of Management.
 
76

 
Alan D. Watson, Ph.D., M.B.A. has served as a director since November 12, 2002. Dr. Watson received his B.S. from the University of N.S.W., his Ph.D. in Chemistry from Australian National University, and his M.B.A. from Northeastern University. Since 2002, Dr. Watson has served as Executive Vice President and Chief Business Officer of Elixir Pharmaceuticals, Inc. Prior to that, he was the Senior Vice President, Corporate Development of Cubist Pharmaceuticals, Inc. from 1999 to 2002.
 
Executive Officers and Significant Employees. The recent business experience of our other executive officers and significant employees or consultants follows.
 
Jack DeFranco, age 61, has served as Chief Operating Officer since January 20, 2005 and is currently providing services to the company as a consultant. From June 18, 2003 until January 20, 2005, he served as our Senior Vice President of Business Development and Marketing. For the ten years prior to joining the company, Mr. DeFranco served as Vice President of Marketing and Business Development for Alliance Pharmaceutical Corp., and he is currently employed with Alliance again as its President and Chief Operating Officer.   Mr. DeFranco received his B.S. from Stephen F. Austin University and an M.B.A. and M.A. from Fairleigh Dickenson University.
 
Larry D. Grant, age 55, has served as a financial consultant to the company since May 11, 2004. Mr. Grant is an independent consultant to the company who provides concentrated interim chief financial officer services, generally to technology companies, for extended periods of time. Unrelated to the company, since 2005, Mr. Grant has also been a Partner in Tatum, LLC, an executive services and consulting firm. From May 2003 to May 2004, Mr. Grant represented the Investors and Board of Directors of Molecular Reflections, Inc. From April 2003 to December 2003, Mr. Grant represented the Investors and Board of Directors of QED Solutions, Inc. From July 2002 to April 2003, Mr. Grant served as acting Chief Financial Officer with Voxiva, Inc. From February 2001 to July 2002, Mr. Grant served as Executive Vice President and Chief Financial Officer with SymRx, Inc. From August 1999 to February 2001, Mr. Grant served as Executive Vice President and Chief Financial Officer with JFX Software, Inc. Mr. Grant is a certified public accountant and has 33 years of experience in providing accounting and financial services.
 
Section 16(a) Beneficial Ownership Reporting Compliance. Section 16(a) of the Securities Exchange Act of 1934, as amended, requires our executive officers, directors and persons who beneficially own more than 10% of our common stock to file initial reports of ownership and changes in ownership with the SEC. Those persons are required by SEC regulations to furnish us with copies of all Section 16(a) forms that they file. To our knowledge, based solely on a review of the copies of those reports furnished to us during the fiscal year ended December 31, 2006, we believe that our executive officers, directors and beneficial owners of more than 10% of our common stock complied with all Section 16(a) filing requirements.
 
Code of Ethics. As of December 31, 2004, we have adopted a code of ethics for principal executives and senior financial officers, which includes our principal executive officer, principal financial officer, principal accounting officer or controller, or persons performing similar functions, as required by sections 406 and 407 of the Sarbanes-Oxley Act of 2002. Our Code of Ethics for Senior Executives and Financial Personnel is referenced as Exhibit 14 and a copy will be provided without charge following the receipt of a written request to Larry D. Grant, IMCOR Pharmaceutical Co., 4660 LaJolla Drive, Suite 500, San Diego, CA 92122.
 
77

 
ITEM 10. EXECUTIVE COMPENSATION.
 
Executive Compensation. The following executive compensation disclosure reflects all compensation awarded to, earned by or paid to the Named Executive Officers (as defined below) for the fiscal years ended December 31,  2005 and 2006. The named executive officers (“Named Executive Officers”) are the company’s Principal Executive Officer and the other executive officers of the company who each received in excess of $100,000 in total salary and bonus for the fiscal year 2006. Compensation is shown in the following table:
 
78


 SUMMARY COMPENSATION TABLE
                                     
Name
and
Principal
Position
 
 
Year
 
 
 
 
 
Salary
($)
 
 
 
Bonus
($)
 
 
 
Stock
Awards
($)
 
 
 
Option
Awards
($) (10)
 
 
Non-Equity
Incentive
Plan
Compen-
sation ($)
 
 
Nonqualified
Deferred
Compensa-
tion Earnings
($)
 
 
All Other
Compen-
sation
Compen-
sation
($)
 
Total
($)
 
 
Brian M. Gallagher, acting principal financial officer and Chairman of the Board of Directors
 
2006
2005
 
$ -0-(1)
$120,000(1)
 
$ -0-
-0-
 
$ -0-
-0-
 
$ 41,696(2)(3)
-0-(2)(3)
 
$ -0-
-0-
 
$ -0-
-0-
 
$ -0-
-X
 
$ 41,696(3)
120,000(1)
Jack DeFranco
former President
and Chief
Executive Officer(8)(9)
 
2006
2005
 
$ 21,189 (4)
237,238 (5)
 
$ -0-
60,000 (6)
 
$ -0-
-0-
 
$ -0-(3)
-0-(3)
 
 
$ -0-
-0-
 
$ -0-
-0-
 
$ -0-
-0-
 
$ 21,189(4)
297,238(5)(6)
Larry D. Grant
financial consultant and
Assistant Secretary
 
2006
2005
 
$ 76,313 (7)
177,600 (7)
 
$ -0-
-0-
 
$ -0-
-0-
 
$ -0-
-0-
 
$ -0-
-0-
 
$ -0-
-0-
 
$ -0-
-0-
 
$ 76,313 (7)
177,600 (7)
 
(1)
We entered into a letter agreement with Dr. Gallagher, the Chairman of our Board of Directors, to receive $10,000 per month in his capacity as Chairman of the Board; however, he has not claimed any monthly compensation for all of 2006, and $80,000 remains unpaid for the months May-December, 2005. Dr. Gallagher is entitled to reimbursement for normal and necessary out-of-pocket business expenses.
   
(2)
Pursuant to Dr. Gallagher’s agreement regarding his status as Chairman of the Board of Directors, he has received an option award to purchase 100,000 shares of common stock subject to vesting over a four year period. On each anniversary of Dr. Gallagher’s continued election as the Chairman of the Board he was to receive a new option to purchase 100,000 shares of common stock at the market price on the date of the grant, to vest over a four year period. However, no options have been granted since February 2005.
   
(3)
Expense reported in 2006 in accordance with Statement of Financial Accounting Standard No. 123R, Share Based Payment (SFAS 123(R)). Expense reported in 2005 in accordance with Accounting Principles Board Opinion No. 25, “Accounting for Stock Issued to Employer,” (“APB No. 25”) and related interpretations. See the notes to the financial statements contained elsewhere herein for additional information. In 2005, option compensation expense for Brian M. Gallagher was calculated on a pro forma basis as if the company had applied the fair value recognition provisions of SFAS No. 123 “Accounting for Stock-Based Compensation” (“SFAS No. 123”), amounted to $103,446. In 2005, option expense for Jack DeFranco, similarly calculated for those options which had vested prior to his employment termination date, amounted to $32,614. Mr. DeFranco’s options have expired without being exercised. Mr. Gallagher’s options have not been exercised.
   
(4)
Reflects consulting fees totaling $21,829.
   
(5)
Includes $44,424 of previously unpaid but accrued vacation.
   
(6)
Reflects a retention bonus which was paid as an inducement to retain his services as an employee (See Note (2)).
   
(7)
Reflects consulting fees totaling $122,900 directly and another $34,000 paid by a stockholder on behalf of the company in 2004. In 2005 and 2006 the amounts were related to consulting fees and were paid directly by the company.
   
(8)
Dr. Williams and Mr. DeFranco were entitled to severance if their employment was terminated without cause, as discussed below.  As part of the employee reduction plan, Dr. Williams was terminated effective May 31, 2005. Mr. DeFranco became a consultant to the Company in November 2005, and is engaged on a part-time, as-needed basis through June 30, 2007.
   
(9)
Mr. DeFranco joined the company on June 18, 2003 as part of the acquisition of the Imagent Business. He served as Chief Operating Officer since January 20, 2005 and served as our Senior Vice President of Business Development and Marketing from June 18, 2003 until January 20, 2005. He became a consultant to the Company in November 2005 and is engaged on a part-time, as-needed basis through June 30, 2007.
   
(10)
Reflects a one-for-twenty reverse split which occurred in March, 2005. 

79

 
 
Stock Options. We did not grant any stock options during the 2005 or 2006 fiscal years under our 2000 Long Term Incentive Compensation Plan.
 
The following table sets forth information about the Named Executive Officers concerning the exercise of options during the last fiscal year and unexercised options held as of the end of the 2006 fiscal year.
 
OUTSTANDING EQUITY AWARDS AT FISCAL YEAR END
         
   
 
Option Awards
 
 
Stock Awards
Name
 
 
 
 
 
 
 
 
 
 
Number
of
Securities
Underlying
Unexercised
Options
(#)
Exercisable
 
 
 
 
Number
of
Securities
Underlying
Unexercised
Options
(#)
Unexercisable
 
 
 
 
 
Equity Incentive
Plan
Awards:
Number of
Securities
Underlying
Unexercised
Unearned
Options
(#)
 
 
 
Option Exercise Price
($)
 
 
 
 
 
 
Option
Expiration
Date
 
 
 
 
 
 
 
 
 
Number
of Shares
or Units
of Stock
That Have
Not
Vested
(#)
 
 
 
 
 
Market
Value of
Shares or
Units of
Stock
That Have
Not Vested
($)
 
 
 
 
 
Equity
Incentive
Plan Awards:
Number of
Unearned
Shares,
Units or
Other Rights
That Have
Not Vested
(#)
 
 
 
Equity
Incentive
Plan
Awards:
Market or
Payout
Value of
Unearned
Shares,
Units or
Other Rights
That Have
Not Vested
($)
Brian M. Gallagher
 
51,250
 
48,750
 
-0-
 
$8.00
 
(1)
 
-0-
 
$-0-
 
-0-
 
$-0-
Jack DeFranco
 
-0-
 
-0-
 
-0-
 
-0-
 
--
 
-0-
 
-0-
 
-0-
 
-0-
Larry D. Grant
 
-0-
 
-0-
 
-0-
 
-0-
 
--
 
-0-
 
-0-
 
-0-
 
-0-
 
__________
(1) 5,000 expire on June 30, 2014 and 95,000 expire on March 4, 2015.
 
Mr. DeFranco is currently a consultant to the company. Mr. DeFranco is bound by his Employee Confidentiality, Inventions and Noncompetition Agreements, as amended (the “Confidentiality Agreement”). The Confidentiality Agreement provides that while we employ Mr. DeFranco and for a period of two years after termination he will not engage in activities that compete with our business. The Confidentiality Agreement also requires Mr. DeFranco to disclose to our board of directors all inventions or other intellectual property discovered or made by him during his employment and twelve months thereafter, if those inventions are related to or useful in our business, or result from duties assigned to that individual or from the use of any of our assets or facilities.
 
 Mr. DeFranco was eligible to receive typical health, life and disability insurance benefits that are available to our other salaried employees and to defer a portion of their salary through our 401(k) plan, but we did not match or make any contributions to the 401(k) plan during the 2005 fiscal year. We do not maintain a pension plan other than our 401(k) plan, and all of our employee benefit plans were terminated as part of our restructuring plan.
 
 Through May, 2005, Mr. Grant provided services to us under a consulting agreement that required us to pay him consulting fees at a rate of $925 per day, plus pay for his reasonable out-of-pocket expenses, and certain transportation expenses between San Diego and the East Coast, and to provide modest interim living accommodations in San Diego. For the balance of 2005 and all of 2006, Mr. Grant continued to provide services to us under the consulting agreement but worked from the East Coast. During 2005, we paid Mr. Grant consulting fees totaling $177,600. In return, during 2005 Mr. Grant provided us with financial and accounting advisory services and spent an average of at least five days per week and at least eight hours per day devoted to our business through May, 2005. For the balance of 2005, Mr. Grant continued to advise the company on average of two days per week. In 2006 Mr. Grant’s time commitment was further reduced to approximately 20 days per quarter on average, during which period we paid Mr. Grant consulting fees totaling $76,313.
 
  Officers generally serve at the discretion of the board of directors. We do not have any compensatory plans or arrangements resulting from resignation, retirement or any other termination of an executive officer’s employment with us.
 
As part of the employee reduction plan, the employment of our CEO and President was terminated effective May 31, 2005. We recorded a reserve for severance (equal to one year’s salary, as required by this individual’s employment contract), amounting to $275,000, as expense during the quarter ending June 30, 2005. This obligation remains unpaid and is accordingly included in accrued expenses at December 31, 2006.
 
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DIRECTOR COMPENSATION
                             
Name
 
 
 
 
Fees Earned or
Paid in Cash ($)
 
 
 
Stock Awards
($)
 
 
Option Awards
($)
 
 
 
Non-Equity
Incentive Plan
Compensation
($)
 
 
Non-Qualified
Deferred
Compensation
Earnings ($)
 
 
All Other
Compensation
($)
 
 
Total ($)
 
 
 
Brian M. Gallagher, Ph.D.
 
$-0- (1)
 
$-0-
 
$-0- (2)
 
$-0-
 
$-0-
 
$-0-
 
$-0-
Darlene M. Deptula-Hicks
 
$-0- (3)
 
$-0-
 
$-0- (4)
 
$-0-
 
$-0-
 
$-0-
 
$-0-
Alan D. Watson
Ph.D.
 
$-0- (5)
 
$-0-
 
$-0- (6)
 
$-0-
 
$-0-
 
$-0-
 
$-0-
Jonathan Fleming
 
$-0- (7)
 
$-0-
 
$-0-
 
$-0-
 
$-0-
 
$-0-
 
$-0-
Richard Dean Ph.D.
 
$-0- (8)
 
$-0-
 
$-0- (9)
 
$-0-
 
$-0-
 
$-0-
 
$-0-
Robert A. Ashley
 
$-0- (10)
 
$-0-
 
$-0- (11)
 
$-0-
 
$-0-
 
$-0-
 
$-0-
                             
Taffy J. Williams Ph.D.
 
$-0- (12)
 
$-0-
 
$-0-
 
$-0-
 
$-0-
 
$-0-
 
$-0-
 
(1) We entered into a letter agreement with Dr. Gallagher, the Chairman of our Board of Directors, to receive $10,000 per month; however, he has not claimed any monthly compensation for all of 2006, and $80,000 remains unpaid for the months May-December, 2005. Dr. Gallagher is entitled to reimbursement for normal and necessary out-of-pocket business expenses.

(2) Pursuant to Dr. Gallagher’s agreement, he has received an option award to purchase 100,000 shares of common stock subject to vesting over a four year period. On each anniversary of Dr. Gallagher’s continued election as the Chairman of the Board he was to receive a new option to purchase 100,000 shares of common stock at the market price on the date of the grant, to vest over a four year period. However, no options have been granted since February 2005.

(3) Ms. Deptula-Hicks is entitled to receive an annual fee of $20,000 and an additional annual fee of $5,000 for membership on the Audit Committee; however, no claims for compensation have been made or accrued for 2006. Ms. Deptula-Hicks is reimbursed for normal and necessary out-of-pocket business expenses.

(4) Ms. Deptula-Hicks is entitled to a bi-annual option grant to acquire 3,000 shares of common stock, subject to quarterly vesting, but no options have been granted since October 2004.

(5) Mr. Watson is entitled to receive an annual fee of $20,000 and an additional annual fee of $3,000 for membership on the Compensation Committee; however, no claims for compensation have been made or accrued for in 2006. Mr. Watson is reimbursed for normal and necessary out-of-pocket business expenses.

(6) Mr. Watson is entitled to a bi-annual option grant to acquire 3,000 shares of common stock, subject to quarterly vesting, but no options have been granted since December 2003.

(7) Mr. Fleming has declined to receive any compensation for his participation on the Board or any of its committees.

(8) Dr. Dean is entitled to receive an annual fee of $20,000 and an additional fee of $5,000 for membership on the Audit Committee and $3,000 for membership on the Compensation Committee, however, no claims for compensation have been made or accrued for 2006. Dr. Dean is entitled to reimbursement of normal and necessary out-of-pocket business expenses.

(9) Dr. Dean is entitled to receive a bi-annual option grant to acquire 3,000 shares of common stock, subject to quarterly vesting, but no options have been granted since December 2003.

(10) Mr. Ashley is entitled to receive an annual fee of $20,000 and an additional annual fee of $5,000 for membership on the Audit Committee; however, no claims for compensation have been made or accrued for 2006. Mr. Ashley is reimbursed for normal and necessary out-of-pocket business expenses.

(11) Mr. Ashley is entitled to receive 3,000 options vesting over two years; however, these options have not been issued to date.

(12) Dr. Williams does not receive any separate compensation for his Board membership or for his Executive Committee membership.
81

 
ITEM 11. SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT AND RELATED STOCKHOLDER MATTERS.
 
Security Ownership of Certain Beneficial Owners and Management. The following table sets forth the approximate beneficial ownership of our common stock as of on March 31, 2007 by directors and executive officers of the Company and any person or group known to us to be the owner of more than five percent of our common stock. Shares beneficially owned by the individuals below through family partnerships or other entities they control are included in the number of shares listed in the table below for that individual.
 
 
Name and Address
of Beneficial Owner(1)
 
Shares of
Common
Stock
Beneficially
Owned(2)
 
Percent of
Class
Outstanding(3)
 
 
 
 
 
 
EXECUTIVE OFFICERS AND DIRECTORS:
 
 
 
 
 
Robert A. Ashley
 
 
-0-
 
 
*
 
 
 
 
 
 
 
 
 
Richard T. Dean
 
 
3,000
(4) 
 
*
 
 
 
 
 
 
 
 
 
Jack DeFranco
 
 
-0-
 
 
*
 
 
 
 
 
 
 
 
 
Darlene M. Deptula-Hicks, M.B.A.
 
 
3,000
(5) 
 
*
 
 
 
 
 
 
 
 
 
Jonathan Fleming/Oxford Bioscience
Partners IV L.P.
225 Berkeley St., Suite 1650
Boston, MA 02216
 
 
4,790,470
(6) 
 
67.5
 
 
 
 
 
 
 
 
 
Brian M. Gallagher, Ph.D.
 
 
75,000
(7) 
 
1.1
 
 
 
 
 
 
 
 
 
Alan D. Watson, Ph.D.
 
 
4,750
(8) 
 
*
 
 
 
 
 
 
 
 
 
Taffy J. Williams, Ph.D.
 
 
-0-
 
 
*
 
 
 
 
 
 
 
 
 
All directors and executive officers as a group--2006 fiscal year (8 persons)
 
 
4,876,220
 
 
67.9
 
 
 
 
 
 
 
 
 
 
OTHER SHAREHOLDERS:
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Oxford Bioscience Partners IV L.P.
225 Berkeley Street, Suite 1650
Boston, MA 02216
 
 
See above.
 
 
 
 
 
*
Constitutes one percent or less of the percent of class outstanding. 

(1)
Unless otherwise indicated, the address of each person named in the table is c/o: IMCOR Pharmaceutical Co., 4660 La Jolla Drive, Suite 500, San Diego, CA 92122.
 
82

 
(2)
With respect to directors and executive officers, based on information furnished by the director or executive officer listed. 

(3)
The percent of class outstanding includes common stock outstanding as of March 31, 2007, and the shares of common stock issuable upon exercise of warrants and options or conversion of other securities within 60 days of March 31, 2007. 

(4)
Includes 3,000 options exercisable within 60 days of March 31, 2007. 

(5)
Includes 3,000 options exercisable within 60 days of March 31, 2007. 

(6)
Includes 46,223 shares and 1,366 warrants held by MRNA Fund II L.P. and 4,606,746 shares and 136,135 warrants held by Oxford Bioscience Partners IV L.P., which Mr. Fleming may be deemed to control. Mr. Fleming disclaims beneficial ownership of these shares for all other purposes.

(7)
Includes 75,000 options exercisable within 60 days of March 31, 2007. 

(8)
Includes 1,250 shares of common stock and options to acquire 3,500 shares of common stock exercisable within 60 days of March 31, 2007. 
 
Change in Control Agreements. We know of no arrangements which could result in a change of control of the company.
 
Securities Authorized for Issuance Under Equity Compensation Plans.

The information provided in the following table is as of December 31, 2006.
 
 
Plan Category
 
Number of
securities to be
issued upon
exercise of
outstanding
options, warrants
and rights (a)
 
Weighted-average exercise price of outstanding
options, warrants
and rights (b)
 
Number of
securities
remaining available
for future issuance
under equity
compensation plans (excluding
securities
reflected in column
(a)) (c)
 
Equity compensation plans approved by security holders
 
 
110,671
 
$
12.29
 
 
1,464,272
 
Equity compensation plans not approved by security holders
 
 
-0-
 
$
-0-
 
 
-0-
 
TOTAL
 
 
110,671
 
$
12.29
 
 
1,464,272
 
 
We have issued the following warrants to purchase shares of our common stock without the prior approval of our stockholders:
 
·  
A warrant to purchase 7,500 shares at $21.60 per share to Broadmark Capital, LLC in connection with a Settlement Agreement and Mutual Release dated as of September 23, 2002 which related to our engagement of Broadmark Capital, LLC as a placement agent,
 
 
83

 
·  
A warrant to purchase 9,500 shares at $50.40 per share to Clinical Regulatory Strategies, LLC in connection with our August 12, 2002 engagement of Clinical Regulatory Strategies, LLC to provide us with certain clinical, regulatory and new product development services, of which only 1,900 are exercisable,
 
·  
A warrant to purchase 188 shares at $884.54 per share to a consultant as of January 24, 2000 in connection with certain consulting services provided by the consultant,
 
·  
Options to purchase on a cashless basis a net aggregate of 34,977 shares issued to Gerald Wolf, M.D. to settle certain intellectual property and related disputes; a portion of these options were previously granted but were amended in 2005, which such amendment is reflected herein,
 
·  
Warrants to purchase an aggregate of 735,881 shares issued to investors and placement agents in our April/June 2004 financing, and
 
·  
A warrant to purchase 66,667 shares of our common stock with an exercise price of $5.40 per share to First Albany Capital, Inc. in connection with certain investment banking services provided to us by First Albany Capital, Inc. in October, 2004.
ITEM 12. CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS.
 
Certain Relationships and Related Transactions. Mi3, Oxford and MRNA purchased shares in the institutional financing which closed in April and June 2004. Jonathan Fleming (a director) is General Partner of OBP Management IV L.P. which is the general partner of Oxford and MRNA. William McPhee (a director at that time) was president of Mi3 Services L.L.C., the general partner of Mi3. These investors also provided capital to us evidenced by secured notes, which were converted into shares of our common stock at $8.00 per share in connection with the April/June 2004 financing. We filed registration statements covering the resale of shares held by these stockholders (which have terminated since then), and we issued additional late registration shares to them as required by the applicable registration rights agreements. We owed Oxford and MRNA $192,233 as of December 31, 2006 pursuant to unsecured notes, plus unpaid interest. The notes bear interest at eight percent annually.
84

 

ITEM 13. EXHIBITS, LIST AND REPORTS ON FORM 8-K. 
 
(a) Exhibits
 
The following is a list of exhibits filed as part of this Form 10-KSB. Exhibits that were previously filed are incorporated by reference. For exhibits incorporated by reference, the location of the exhibit in the previous filings is indicated in parentheses.
 
EXHIBIT
NO.
 
DESCRIPTION
+2.1
 
Asset Purchase Agreement dated as of June 10, 2003 by and between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and Alliance Pharmaceutical Corp. (Filed as Exhibit 2.1 to the company’s Form 8-K dated June 20, 2003 and incorporated herein by reference.)
 
 
 
+3.1
 
Articles of Incorporation of IMCOR Pharmaceutical Co., as amended. (Filed as Exhibit 3.1 to the company’s Form 10-KSB dated March 31, 2005 and incorporated herein by reference.)
 
 
 
+3.2
 
Certificate of Designation, Preferences and Rights of Series A Preferred Stock. (Filed as part of Exhibit 3.1 to the company’s 8-K filed on November 11, 2004 and incorporated herein by reference.)
 
 
 
+3.3
 
Amended and Restated Bylaws of IMCOR Pharmaceutical Co. (Filed as Exhibit C to the company’s Information Statement on Form DEF 14C dated December 23, 2002 and incorporated herein by reference.)
 
+4.1
 
Form of Registration Rights Agreement entered into by and between IMCOR Pharmaceutical Co. and each purchaser signatory thereto dated April 14, 2004. (Filed as Exhibit 4.13 to the company’s 10-QSB for the quarter ended March 31, 2004 and incorporated herein by reference.)
 
 
 
+4.2
 
Form of Warrant Agreement entered into by and between IMCOR Pharmaceutical Co. and each purchaser signatory thereto dated as of April 14, 2004. (Filed as Exhibit 4.12 to the company’s 10-QSB for the quarter ended March 31, 2004 and incorporated herein by reference.)
 
 
 
+4.3
 
Form of Registration Rights Agreement entered into by and among IMCOR Pharmaceutical Co. Oxford Bioscience Partners IV L.P., MRNA Fund II L.P. and Mi3 LP dated April 19, 2004. (Filed as Exhibit 4.15 to the company’s 10-QSB for the quarter ended March 31, 2004 and incorporated herein by reference.)
 
 
 
+4.4
 
Form of Registration Rights Agreement entered into by and between IMCOR Pharmaceutical Co. and Bristol-Myers Squibb Medical Imaging, Inc. dated as of October 29, 2004. (Filed as Exhibit 10.3 to the company’s 8-K filed on November 4, 2004 and incorporated herein by reference.)
 
85

 
+4.5
 
Registration Rights Agreement entered into as of November 12, 2002 by and among IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.), Mi3 L.P., Oxford Bioscience Partners IV L.P., MRNA Fund II L.P. and Tannebaum, LLC. (Filed as Exhibit D to the company’s Proxy Statement on Form DEFM 14A dated September 12, 2002 and incorporated herein by reference.)
 
 
 
+4.6
 
Form of Registration Rights Agreement dated as of December 30, 2002 entered into by and between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and each of Oxford Bioscience Partners IV L.P., MRNA Fund II L.P., DMG Legacy Institutional Fund LLC, DMG Legacy Fund LLC, and DMG Legacy International Ltd. (Filed as Exhibit 10.7 to the company’s Annual Report on Form 10-K for dated December 31, 2002 and incorporated herein by reference.)
 
 
 
+4.7
 
Incentive Stock Option Award Agreement entered into by and between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and Taffy J. Williams, Ph.D. dated May 17, 2000. (Filed as Exhibit 10.4 to the company’s Current Report on Form 8-K dated May 17, 2001 and incorporated herein by reference.)
 
 
 
 +4.8
 
Incentive Stock Option Award Agreement entered into by IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and Brooks Boveroux dated August 1, 2000. (Filed as Exhibit 10.13 to the company’s Annual Report on Form 10-K dated December 31, 2000 and incorporated herein by reference.)
 
 
 
+4.9
 
Warrant to Purchase Shares of Common Stock dated October 20, 1999 between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and Élan International Services, Ltd. (Filed as Exhibit 10.9 to the company’s Quarterly Report on Form 10-QSB for the quarter ended September 30, 1999 and incorporated herein by reference.)
 
+4.10
 
Warrant Agreement dated as of November 12, 2002 between Broadmark Capital LLC and IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.). (Filed as Exhibit 10.27 to the company’s Annual Report on Form 10-K for the year ended December 31, 2002 and incorporated herein by reference.)
 
 
 
+4.11
 
Non-Qualified Stock Option Award Agreement dated as of January 14, 2004 by and between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and Taffy J. Williams, Ph.D. (Filed as Exhibit 4.11 to the company’s Annual Report on Form 10-KSB for the year ended December 31, 2003 and incorporated herein by reference.)
 
 
 
+4.12
 
Form of Senior Secured Promissory Note dated June 4, 2004 between IMCOR Pharmaceutical Co. and Xmark Fund, L.P. (Filed as Exhibit 4.12 to the company’s registration statement on Form SB-2 filed on August 3, 2004 and incorporated herein by reference.)
 
86

 
+4.13
 
Form of Senior Secured Promissory Note dated June 4, 2004 between IMCOR Pharmaceutical Co. and Xmark Fund, Ltd. (Filed as Exhibit 4.13 to the company’s registration statement on Form SB-2 filed on August 3, 2004 and incorporated herein by reference.)
 
 
 
+9.1
 
Voting, Drag-Along and Right of First Refusal Agreement entered into as of November 12, 2002 by and among Robert J. Weinstein, M.D., Stuart P. Levine, Tannebaum, LLC, Mi3 L.P., Oxford Bioscience Partners IV L.P. and MRNA Fund II L.P. (Filed as Exhibit G to the company’s Proxy Statement on Form DEFM 14A dated September 12, 2002 and incorporated herein by reference.)
 
 
 
+10.1
 
Letter Agreement entered into as of August 29, 2002 by and between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and Clinical Regulatory Strategies, LLC (Filed as Exhibit 10.2 to the company’s quarterly report on Form 10-Q for the quarter ended September 30, 2002 and incorporated herein by reference.)
 
 
 
+10.3
 
Form of Indemnification Agreement entered into by and between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and each Director and Senior Vice President of the company. (Filed as Exhibit 10.13 to the company’s Annual Report on Form 10-K for dated December 31, 2002 and incorporated herein by reference.)
 
 
 
 +10.5
 
License Agreement effective as of September 30, 1999 between The General Hospital Corporation and Photogen, Inc. (Filed as Exhibit 10.7 to the company’s Quarterly Report on Form 10-QSB for the quarter ended September 30, 1999 and incorporated herein by reference.) Confidential portions of this exhibit were redacted.
 
 
 
+10.6
 
Forbearance Agreement dated June, 2004 by and between IMCOR Pharmaceutical Co. and Philips Medical Capital, LLC. (Filed as Exhibit 10.22 to the company’s registration statement on Form SB-2 filed on August 3, 2004 and incorporated herein by reference.)
 
 
 
+10.7
 
Exchange Agreement dated as of June 4, 2004 by and among IMCOR Pharmaceutical Co., Xmark Fund, L.P., Xmark Fund Ltd., Oxford Bioscience Partners IV L.P., MRNA Fund II, L.P. and Mi3 L.P. (Filed as Exhibit 10.23 to the company’s registration statement on Form SB-2 filed on August 3, 2004 and incorporated herein by reference.)
 
+10.8
 
Single-Tenant Industrial Lease dated November 7, 1997 by and between WHAMC Real Estate Limited Partnership and Alliance Pharmaceutical Co. (Filed as Exhibit 10.1 to the company’s quarterly report on Form 10-QSB for the quarter ended September 30, 2004 and incorporated herein by reference.)
 
87

 
+10.9
 
Landlord Consent to Assignment and Assumption dated as of June 18, 2003 by and among IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.), EOP-Industrial Portfolio, L.L.C. and Alliance Pharmaceutical Corp. (Filed as Exhibit 10.2 to the company’s quarterly report on Form 10-QSB for the quarter ended September 30, 2004 and incorporated herein by reference.)
 
 
 
+10.10
 
Equipment Lease between Picker Financial Group, L.L.C. and Photogen, Inc. dated October 25, 1999. (Filed as Exhibit 10.37 to the company’s Annual Report on Form 10-KSB for the year ended December 31, 1999 and incorporated herein by reference.)
 
 
 
+10.11
 
Going Forward Agreement dated as of May 2, 2003 by and among IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.), Xmark Fund, L.P., and Xmark Fund, Ltd. (Filed as Exhibit 10.1 to the company’s 8-K filed on June 20, 2003 and incorporated herein by reference.)
 
 
 
+10.12
 
Security Agreement dated as of June 18, 2003 by and among IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.), Xmark Fund, L.P. and Xmark Fund, Ltd. (Filed as Exhibit 10.2 to the company’s 8-K filed on June 20, 2003 and incorporated herein by reference.)
 
 
 
+10.13
 
Patent and Trademark Security Agreement dated as of June 18, 2003 by and among IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.), Xmark Fund, L.P., and Xmark Fund, Ltd. (Filed as Exhibit 10.3 to the company’s 8-K filed on June 20, 2003 and incorporated herein by reference.)
 
 
 
+10.14
 
Security Agreement dated as of June 18, 2003 by and among IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.), Oxford Bioscience Partners IV L.P., MRNA Fund II L.P. and Mi3 LP. (Filed as Exhibit 10.5 to the company’s 8-K filed on June 20, 2003 and incorporated herein by reference.)
 
 
 
+10.15
 
Patent and Trademark Security Agreement dated as of as of June 18, 2003 by and among IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.), Oxford Bioscience Partners IV L.P., MRNA Fund II L.P. and Mi3 LP. (Filed as Exhibit 10.6 to the company’s 8-K filed on June 20, 2003 and incorporated herein by reference.)
 
 
 
 +10.16
 
Equipment Lease dated as of June 18, 2003 by and between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and Baxter Healthcare Corporation. (Filed as Exhibit 10.8 to the company’s 8-K filed on June 20, 2003 and incorporated herein by reference.)
 
 
 
+10.17
 
Letter Agreement dated as of August 18, 2003 by and among IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.), Xmark Fund, Ltd. and Xmark Fund, L.P. (Filed as Exhibit 10.1 to the company’s Form 8-K filed on August 20, 2003 and incorporated herein by reference.)
 
88

 
 +10.18
 
Amended and Restated Letter Agreement dated February 8, 2005 by and between IMCOR Pharmaceutical Co. and Jack DeFranco. (Filed as Exhibit 10.18 to the company’s Form 10-KSB dated March 31, 2005 and incorporated herein by reference.)
 
 
 
+10.19
 
Letter Agreement dated July 23, 2003 by and between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and Taffy J. Williams, Ph.D. (Filed as Exhibit 10.5 to the company’s Form 10-QSB for the quarter ended September 30, 2003 and incorporated herein by reference).
 
 
 
+10.20
 
Form of Letter Agreement by and between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and each outside director. (Filed as Exhibit 10.20 to the Company’s Form 10-KSB for the year ended December 31, 2003 and incorporated herein by reference.)
 
 
 
+10.21
 
License Agreement dated December 16, 2003 by and between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and Kyosei Pharmaceutical Co. Ltd. Confidential portions of this exhibit were redacted. (Filed as Exhibit 10.1 to the company’s report on Form 8-K filed on December 18, 2003 and incorporated herein by reference.)
 
 
 
+10.22
 
Termination Agreement dated June 9, 2004 by and among IMCOR Pharmaceutical Co. (f/k/a/ Photogen Technologies, Inc.), Élan Corporation, plc, Élan Pharma International Ltd., Élan International Services, Ltd., and Sentigen, Ltd. Confidential portions of this exhibit were redacted. (Filed as Exhibit 10.11 to the company’s quarterly report on Form 10-QSB for the quarter ended September 30, 2004 and incorporated herein by reference.)
 
 
 
+10.23
 
License Agreement dated June 9, 2004 between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and Élan Pharma International Ltd. Confidential portions of this exhibit were redacted. (Filed as Exhibit 10.12 to the company’s quarterly report on Form 10-QSB for the quarter ended September 30, 2004 and incorporated herein by reference.)
 
 
 
+10.24
 
Letter Agreement dated June 9, 2004 by and among IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.), Élan Drug Delivery, Inc. and Élan Pharma International Ltd. Confidential Portions of this exhibit were redacted. (Filed as Exhibit 10.13 to the company’s quarterly report on Form 10-QSB for the quarter ended September 30, 2004 and incorporated herein by reference.)
 
 
 
+10.25
 
Letter Agreement dated June 27, 2004 by and between IMCOR Pharmaceutical Co. and Brian M. Gallagher. (Filed as Exhibit 10.14 to the company’s quarterly report on Form 10-QSB for the quarter ended June 30, 2004.)
 
 
 
+10.26
 
Cross License Agreement dated as of October 29, 2004 by and between Bristol-Myers Squibb Medical Imaging, Inc. and IMCOR Pharmaceutical Co. Confidential portions of this exhibit were redacted. (Filed as Exhibit 10.1 to the company’s 8-K filed on November 4, 2004 and incorporated herein by reference.)
 
89

 
 +10.27
 
License Agreement originally dated as of September 23, 1997 amended and restated in its entirety as of February 22, 2002 by and between Alliance Pharmaceutical Corp. and Schering Aktiengesellschaft. Confidential portions of this exhibit were redacted. (Filed as Exhibit 10.1 to the company’s quarterly report on Form 10-QSB for the quarter ended September 30, 2004 and incorporated herein by reference.)
 
 
 
+10.28
 
Settlement and Worldwide License Agreement dated as of January 31, 2001 by and among Bracco International B.V., Schering Aktiengesellschaft and Alliance Pharmaceutical Corp. Confidential portions of this exhibit were redacted. (Filed as Exhibit 10.2 to the company’s quarterly report on Form 10-QSB for the quarter ended September 30, 2004 and incorporated herein by reference.)
 
 
 
+10.29
 
Amended and Restated Supply Agreement dated as of October 8, 2003 by and between Genzyme Corporation and IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.). (Filed as Exhibit 10.29 to the company’s report on Form 10-KSB/A for the year ended December 31, 2004 and incorporated herein by reference. Certain information in this exhibit was omitted and filed separately with the Securities and Exchange Commission pursuant to a confidential treatment request under Rule 24B-2 of the Securities Exchange Act of 1934, as amended.)
 
 
 
+10.30
 
Amendment and Assignment Agreement dated as of August 18, 2003 by and among IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.), Cardinal Health 411, Inc., Cardinal Health 105, Inc. (f/k/a CORD Logistics, Inc., n/k/a Cardinal Specialty Pharmacy Distribution) and Alliance Pharmaceutical Co. Confidential portions of this exhibit were redacted. (Filed as Exhibit 10.4 to the Company’s 10-QSB filed on November 20, 2003.)
 
 
 
+10.31
 
Exclusive Distribution Agreement dated as of April 1, 2002 by and between Alliance Pharmaceutical Co. and CORD Logistics, Inc. (n/k/a Cardinal Specialty Pharmacy Distribution). (Filed as Exhibit 10.31 to the company’s report on Form 10-KSB/A for the year ended December 31, 2004 and incorporated herein by reference. Certain information in this exhibit was omitted and filed separately with the Securities and Exchange Commission pursuant to a confidential treatment request under Rule 24B-2 of the Securities Exchange Act of 1934, as amended.)
 
 
 
+10.32
 
Amended and Restated License Agreement dated as of November 13, 2006 by and between Kyosei Pharmaceutical Co., Ltd. and IMCOR Pharmaceutical Co. (Filed as Exhibit 10.1 to the company’s 10-QSB for the quarter ended September 30, 2006 and incorporated herein by reference. Confidential information in this exhibit was omitted and filed separately with the Securities and Exchange Commission pursuant to a confidential treatment request under Rule 24B-2 of the Securities Exchange Act of 1934, as amended.
 
90

 
+14
 
Code of Ethics for Principal Executive and Senior Financial Officers effective as of December 31, 2004. (Filed as Exhibit 14 to the company’s Form 10-KSB dated March 31, 2005 and incorporated herein by reference.)
 
 
 
+21
 
List of subsidiaries of the company (Filed as Exhibit 21 to the company’s Form 10-K for the year ended December 31, 2002 and incorporated herein by reference.)
 
 
 
*31.1
 
Certification of Principal Executive Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.
 
 
 
*31.2
 
Certification of Principal Financial Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.
 
 
 
*32.1
 
Certification of Principal Executive Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
 
 
 
*32.2
 
Certification of Principal Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
 
+ Incorporated by Reference.
* Filed herewith.
 
 (b) Reports on Form 8-K.

On November 28, 2006 the company filed an 8-K announcing the merger of its independent accounting firm, Peterson & Co., LLP with Squar, Milner, Miranda & Williamson, LLP.
 
On December 8, 2006 the company filed an amendment to the 8-K filed on November 28, 2006 to satisfy technical Securities and Exchange Commission requirements relating to the disclosure of the merger between Peterson & Co., LLP and Squar, Milner, Miranda & Williamson, LLP.
ITEM 14. PRINCIPAL ACCOUNTANT FEES AND SERVICES.
 
Independent Auditors’ Fees
 
The aggregate fees billed for professional services rendered by the principal accountant for each of the fiscal years ended December 31, 2005 and 2006 for the audit of the Company’s annual financial statements and review of the financial statements included in our quarterly reports on Form 10-QSB, and services that are normally provided by the accountant in connection with statutory and regulatory filings (including review of registration statements under “Audit Related Fees”) or engagements for these fiscal periods, were as follows:
 
 
 
Year ended December 31, 2005
 
Year ended December 31, 2006
 
Audit Fees
 
$
183,795
 
$
79,947
 
Audit Related Fees
 
$
7,050
   
None
 
Tax Fees
   
None
 
$
19,094
 
All Other Fees
   
None
   
None
 
Total
 
$
190,845
 
$
99,041
 
 
91

 
Audit Committee Pre-Approval Policy. Pursuant to the terms of our Audit Committee’s charter, our Audit Committee pre-approves all auditing services (which may entail providing comfort letters in connection with securities underwritings) and non-audit services proposed to be provided by the Company’s independent certified public accountant, except for non-audit services within the de minimus exception under Section 10A(i)(B) of the Exchange Act. In this connection, the Audit Committee has the authority to appoint one or more of its members to approve services, provided that the decisions made by such designees between meetings of the Audit Committee shall be presented to the full Audit Committee at the next meeting thereof. All of the services provided to the Company by Squar, Milner, Peterson, Miranda & Williamson, LLP (formerly Peterson & Co., LLP) during the fiscal years ended December 31, 2005 and December 31, 2006 were pre-approved by the Audit Committee.
92

 

 SIGNATURES

In accordance with Section 13 or 15(d) of the Exchange Act, the registrant caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.
     
 
IMCOR PHARMACEUTICALS CO.
 
 
 
 
 
 
Date: Apri1 16, 2007 By:   /s/ Brian Gallagher
 
Brian Gallagher
(Chairman of the Board and Acting Principal Financial Officer) 
 
93

 
 
In accordance with the Exchange Act, this report has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated.
 
Signature
 
Title
 
Date
 
 
 
 
 
 
 
             
By:
 
/s/ Taffy J. Williams, Ph.D.       
 
Director
 
April 16, 2007
 
 

Taffy J. Williams, Ph.D.
 
 
 
 
 
 
 
 
 
 
 
             
By:
 
/s/ Darlene M. Deptula-Hicks    
 
Director
 
April 16, 2007
 
 

Darlene M. Deptula - Hicks 
 
 
 
 
 
 
 
 
 
 
 
             
By:
 
/s/ Alan D. Watson, Ph.D.        
 
Director
 
April 16, 2007
 
 

Alan D. Watson, Ph.D. 
 
 
 
 
 
 
 
 
 
 
 
             
By:
 
/s/ Jonathan Fleming                
 
Director
 
April 16, 2007
 
 

Jonathan Fleming
 
 
 
 
 
 
 
 
 
 
 
             
By:
 
/s/ Richard Dean, Ph.D.           
 
Director
 
April 16, 2007
 
 

Richard Dean, Ph.D.
 
 
 
 
 
 
 
 
 
 
 
             
By:
 
/s/ Robert A. Ashley                
 
Director
 
April 16, 2007
 
 

Robert A. Ashley
 
 
 
 
 
 
 
 
 
 
 
             
By:
 
/s/ Brian M. Gallagher, Ph.D. 
 
Director
 
April 16, 2007
 
 

Brian M. Gallagher, Ph.D. 
 
 
 
 
 
94

 
EXHIBIT INDEX
 
EXHIBIT
NO.
 
DESCRIPTION
+2.1
 
Asset Purchase Agreement dated as of June 10, 2003 by and between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and Alliance Pharmaceutical Corp. (Filed as Exhibit 2.1 to the company’s Form 8-K dated June 20, 2003 and incorporated herein by reference.)
 
 
 
+3.1
 
Articles of Incorporation of IMCOR Pharmaceutical Co., as amended. (Filed as Exhibit 3.1 to the company’s Form 10-KSB dated March 31, 2005 and incorporated herein by reference.)
 
 
 
+3.2
 
Certificate of Designation, Preferences and Rights of Series A Preferred Stock. (Filed as part of Exhibit 3.1 to the company’s 8-K filed on November 11, 2004 and incorporated herein by reference.)
 
 
 
+3.3
 
Amended and Restated Bylaws of IMCOR Pharmaceutical Co. (Filed as Exhibit C to the company’s Information Statement on Form DEF 14C dated December 23, 2002 and incorporated herein by reference.)
 
+4.1
 
Form of Registration Rights Agreement entered into by and between IMCOR Pharmaceutical Co. and each purchaser signatory thereto dated April 14, 2004. (Filed as Exhibit 4.13 to the company’s 10-QSB for the quarter ended March 31, 2004 and incorporated herein by reference.)
 
 
 
+4.2
 
Form of Warrant Agreement entered into by and between IMCOR Pharmaceutical Co. and each purchaser signatory thereto dated as of April 14, 2004. (Filed as Exhibit 4.12 to the company’s 10-QSB for the quarter ended March 31, 2004 and incorporated herein by reference.)
 
 
 
+4.3
 
Form of Registration Rights Agreement entered into by and among IMCOR Pharmaceutical Co. Oxford Bioscience Partners IV L.P., MRNA Fund II L.P. and Mi3 LP dated April 19, 2004. (Filed as Exhibit 4.15 to the company’s 10-QSB for the quarter ended March 31, 2004 and incorporated herein by reference.)
 
 
 
+4.4
 
Form of Registration Rights Agreement entered into by and between IMCOR Pharmaceutical Co. and Bristol-Myers Squibb Medical Imaging, Inc. dated as of October 29, 2004. (Filed as Exhibit 10.3 to the company’s 8-K filed on November 4, 2004 and incorporated herein by reference.)
 
 
 
+4.5
 
Registration Rights Agreement entered into as of November 12, 2002 by and among IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.), Mi3 L.P., Oxford Bioscience Partners IV L.P., MRNA Fund II L.P. and Tannebaum, LLC. (Filed as Exhibit D to the company’s Proxy Statement on Form DEFM 14A dated September 12, 2002 and incorporated herein by reference.)
 
95

 
+4.6
 
Form of Registration Rights Agreement dated as of December 30, 2002 entered into by and between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and each of Oxford Bioscience Partners IV L.P., MRNA Fund II L.P., DMG Legacy Institutional Fund LLC, DMG Legacy Fund LLC, and DMG Legacy International Ltd. (Filed as Exhibit 10.7 to the company’s Annual Report on Form 10-K for dated December 31, 2002 and incorporated herein by reference.)
 
 
 
+4.7
 
Incentive Stock Option Award Agreement entered into by and between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and Taffy J. Williams, Ph.D. dated May 17, 2000. (Filed as Exhibit 10.4 to the company’s Current Report on Form 8-K dated May 17, 2001 and incorporated herein by reference.)
 
 
 
 +4.8
 
Incentive Stock Option Award Agreement entered into by IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and Brooks Boveroux dated August 1, 2000. (Filed as Exhibit 10.13 to the company’s Annual Report on Form 10-K dated December 31, 2000 and incorporated herein by reference.)
 
 
 
+4.9
 
Warrant to Purchase Shares of Common Stock dated October 20, 1999 between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and Élan International Services, Ltd. (Filed as Exhibit 10.9 to the company’s Quarterly Report on Form 10-QSB for the quarter ended September 30, 1999 and incorporated herein by reference.)
 
+4.10
 
Warrant Agreement dated as of November 12, 2002 between Broadmark Capital LLC and IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.). (Filed as Exhibit 10.27 to the company’s Annual Report on Form 10-K for the year ended December 31, 2002 and incorporated herein by reference.)
 
 
 
+4.11
 
Non-Qualified Stock Option Award Agreement dated as of January 14, 2004 by and between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and Taffy J. Williams, Ph.D. (Filed as Exhibit 4.11 to the company’s Annual Report on Form 10-KSB for the year ended December 31, 2003 and incorporated herein by reference.)
 
 
 
+4.12
 
Form of Senior Secured Promissory Note dated June 4, 2004 between IMCOR Pharmaceutical Co. and Xmark Fund, L.P. (Filed as Exhibit 4.12 to the company’s registration statement on Form SB-2 filed on August 3, 2004 and incorporated herein by reference.)
 
96

 
+4.13
 
Form of Senior Secured Promissory Note dated June 4, 2004 between IMCOR Pharmaceutical Co. and Xmark Fund, Ltd. (Filed as Exhibit 4.13 to the company’s registration statement on Form SB-2 filed on August 3, 2004 and incorporated herein by reference.)
 
 
 
+9.1
 
Voting, Drag-Along and Right of First Refusal Agreement entered into as of November 12, 2002 by and among Robert J. Weinstein, M.D., Stuart P. Levine, Tannebaum, LLC, Mi3 L.P., Oxford Bioscience Partners IV L.P. and MRNA Fund II L.P. (Filed as Exhibit G to the company’s Proxy Statement on Form DEFM 14A dated September 12, 2002 and incorporated herein by reference.)
 
 
 
+10.1
 
Letter Agreement entered into as of August 29, 2002 by and between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and Clinical Regulatory Strategies, LLC (Filed as Exhibit 10.2 to the company’s quarterly report on Form 10-Q for the quarter ended September 30, 2002 and incorporated herein by reference.)
 
 
 
+10.3
 
Form of Indemnification Agreement entered into by and between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and each Director and Senior Vice President of the company. (Filed as Exhibit 10.13 to the company’s Annual Report on Form 10-K for dated December 31, 2002 and incorporated herein by reference.)
 
 
 
 +10.5
 
License Agreement effective as of September 30, 1999 between The General Hospital Corporation and Photogen, Inc. (Filed as Exhibit 10.7 to the company’s Quarterly Report on Form 10-QSB for the quarter ended September 30, 1999 and incorporated herein by reference.) Confidential portions of this exhibit were redacted.
 
 
 
+10.6
 
Forbearance Agreement dated June, 2004 by and between IMCOR Pharmaceutical Co. and Philips Medical Capital, LLC. (Filed as Exhibit 10.22 to the company’s registration statement on Form SB-2 filed on August 3, 2004 and incorporated herein by reference.)
 
 
 
+10.7
 
Exchange Agreement dated as of June 4, 2004 by and among IMCOR Pharmaceutical Co., Xmark Fund, L.P., Xmark Fund Ltd., Oxford Bioscience Partners IV L.P., MRNA Fund II, L.P. and Mi3 L.P. (Filed as Exhibit 10.23 to the company’s registration statement on Form SB-2 filed on August 3, 2004 and incorporated herein by reference.)
 
+10.8
 
Single-Tenant Industrial Lease dated November 7, 1997 by and between WHAMC Real Estate Limited Partnership and Alliance Pharmaceutical Co. (Filed as Exhibit 10.1 to the company’s quarterly report on Form 10-QSB for the quarter ended September 30, 2004 and incorporated herein by reference.)
 
97

 
+10.9
 
Landlord Consent to Assignment and Assumption dated as of June 18, 2003 by and among IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.), EOP-Industrial Portfolio, L.L.C. and Alliance Pharmaceutical Corp. (Filed as Exhibit 10.2 to the company’s quarterly report on Form 10-QSB for the quarter ended September 30, 2004 and incorporated herein by reference.)
 
 
 
+10.10
 
Equipment Lease between Picker Financial Group, L.L.C. and Photogen, Inc. dated October 25, 1999. (Filed as Exhibit 10.37 to the company’s Annual Report on Form 10-KSB for the year ended December 31, 1999 and incorporated herein by reference.)
 
 
 
+10.11
 
Going Forward Agreement dated as of May 2, 2003 by and among IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.), Xmark Fund, L.P., and Xmark Fund, Ltd. (Filed as Exhibit 10.1 to the company’s 8-K filed on June 20, 2003 and incorporated herein by reference.)
 
 
 
+10.12
 
Security Agreement dated as of June 18, 2003 by and among IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.), Xmark Fund, L.P. and Xmark Fund, Ltd. (Filed as Exhibit 10.2 to the company’s 8-K filed on June 20, 2003 and incorporated herein by reference.)
 
 
 
+10.13
 
Patent and Trademark Security Agreement dated as of June 18, 2003 by and among IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.), Xmark Fund, L.P., and Xmark Fund, Ltd. (Filed as Exhibit 10.3 to the company’s 8-K filed on June 20, 2003 and incorporated herein by reference.)
 
 
 
+10.14
 
Security Agreement dated as of June 18, 2003 by and among IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.), Oxford Bioscience Partners IV L.P., MRNA Fund II L.P. and Mi3 LP. (Filed as Exhibit 10.5 to the company’s 8-K filed on June 20, 2003 and incorporated herein by reference.)
 
 
 
+10.15
 
Patent and Trademark Security Agreement dated as of as of June 18, 2003 by and among IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.), Oxford Bioscience Partners IV L.P., MRNA Fund II L.P. and Mi3 LP. (Filed as Exhibit 10.6 to the company’s 8-K filed on June 20, 2003 and incorporated herein by reference.)
 
 
 
 +10.16
 
Equipment Lease dated as of June 18, 2003 by and between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and Baxter Healthcare Corporation. (Filed as Exhibit 10.8 to the company’s 8-K filed on June 20, 2003 and incorporated herein by reference.)
 
 
 
+10.17
 
Letter Agreement dated as of August 18, 2003 by and among IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.), Xmark Fund, Ltd. and Xmark Fund, L.P. (Filed as Exhibit 10.1 to the company’s Form 8-K filed on August 20, 2003 and incorporated herein by reference.)
 
98

 
 +10.18
 
Amended and Restated Letter Agreement dated February 8, 2005 by and between IMCOR Pharmaceutical Co. and Jack DeFranco. (Filed as Exhibit 10.18 to the company’s Form 10-KSB dated March 31, 2005 and incorporated herein by reference.)
 
 
 
+10.19
 
Letter Agreement dated July 23, 2003 by and between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and Taffy J. Williams, Ph.D. (Filed as Exhibit 10.5 to the company’s Form 10-QSB for the quarter ended September 30, 2003 and incorporated herein by reference).
 
 
 
+10.20
 
Form of Letter Agreement by and between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and each outside director. (Filed as Exhibit 10.20 to the Company’s Form 10-KSB for the year ended December 31, 2003 and incorporated herein by reference.)
 
 
 
+10.21
 
License Agreement dated December 16, 2003 by and between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and Kyosei Pharmaceutical Co. Ltd. Confidential portions of this exhibit were redacted. (Filed as Exhibit 10.1 to the company’s report on Form 8-K filed on December 18, 2003 and incorporated herein by reference.)
 
 
 
+10.22
 
Termination Agreement dated June 9, 2004 by and among IMCOR Pharmaceutical Co. (f/k/a/ Photogen Technologies, Inc.), Élan Corporation, plc, Élan Pharma International Ltd., Élan International Services, Ltd., and Sentigen, Ltd. Confidential portions of this exhibit were redacted. (Filed as Exhibit 10.11 to the company’s quarterly report on Form 10-QSB for the quarter ended September 30, 2004 and incorporated herein by reference.)
 
 
 
+10.23
 
License Agreement dated June 9, 2004 between IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.) and Élan Pharma International Ltd. Confidential portions of this exhibit were redacted. (Filed as Exhibit 10.12 to the company’s quarterly report on Form 10-QSB for the quarter ended September 30, 2004 and incorporated herein by reference.)
 
 
 
+10.24
 
Letter Agreement dated June 9, 2004 by and among IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.), Élan Drug Delivery, Inc. and Élan Pharma International Ltd. Confidential Portions of this exhibit were redacted. (Filed as Exhibit 10.13 to the company’s quarterly report on Form 10-QSB for the quarter ended September 30, 2004 and incorporated herein by reference.)
 
 
 
+10.25
 
Letter Agreement dated June 27, 2004 by and between IMCOR Pharmaceutical Co. and Brian M. Gallagher. (Filed as Exhibit 10.14 to the company’s quarterly report on Form 10-QSB for the quarter ended June 30, 2004.)
 
99

 
+10.26
 
Cross License Agreement dated as of October 29, 2004 by and between Bristol-Myers Squibb Medical Imaging, Inc. and IMCOR Pharmaceutical Co. Confidential portions of this exhibit were redacted. (Filed as Exhibit 10.1 to the company’s 8-K filed on November 4, 2004 and incorporated herein by reference.)
 
 
 
 +10.27
 
License Agreement originally dated as of September 23, 1997 amended and restated in its entirety as of February 22, 2002 by and between Alliance Pharmaceutical Corp. and Schering Aktiengesellschaft. Confidential portions of this exhibit were redacted. (Filed as Exhibit 10.1 to the company’s quarterly report on Form 10-QSB for the quarter ended September 30, 2004 and incorporated herein by reference.)
 
 
 
+10.28
 
Settlement and Worldwide License Agreement dated as of January 31, 2001 by and among Bracco International B.V., Schering Aktiengesellschaft and Alliance Pharmaceutical Corp. Confidential portions of this exhibit were redacted. (Filed as Exhibit 10.2 to the company’s quarterly report on Form 10-QSB for the quarter ended September 30, 2004 and incorporated herein by reference.)
 
 
 
+10.29
 
Amended and Restated Supply Agreement dated as of October 8, 2003 by and between Genzyme Corporation and IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.). (Filed as Exhibit 10.29 to the company’s report on Form 10-KSB/A for the year ended December 31, 2004 and incorporated herein by reference. Certain information in this exhibit was omitted and filed separately with the Securities and Exchange Commission pursuant to a confidential treatment request under Rule 24B-2 of the Securities Exchange Act of 1934, as amended.)
 
 
 
+10.30
 
Amendment and Assignment Agreement dated as of August 18, 2003 by and among IMCOR Pharmaceutical Co. (f/k/a Photogen Technologies, Inc.), Cardinal Health 411, Inc., Cardinal Health 105, Inc. (f/k/a CORD Logistics, Inc., n/k/a Cardinal Specialty Pharmacy Distribution) and Alliance Pharmaceutical Co. Confidential portions of this exhibit were redacted. (Filed as Exhibit 10.4 to the Company’s 10-QSB filed on November 20, 2003.)
 
 
 
+10.31
 
Exclusive Distribution Agreement dated as of April 1, 2002 by and between Alliance Pharmaceutical Co. and CORD Logistics, Inc. (n/k/a Cardinal Specialty Pharmacy Distribution). (Filed as Exhibit 10.31 to the company’s report on Form 10-KSB/A for the year ended December 31, 2004 and incorporated herein by reference. Certain information in this exhibit was omitted and filed separately with the Securities and Exchange Commission pursuant to a confidential treatment request under Rule 24B-2 of the Securities Exchange Act of 1934, as amended.)
 
100

 
+10.32
 
Amended and Restated License Agreement dated as of November 13, 2006 by and between Kyosei Pharmaceutical Co., Ltd. and IMCOR Pharmaceutical Co. (Filed as Exhibit 10.1 to the company’s 10-QSB for the quarter ended September 30, 2006 and incorporated herein by reference. Confidential information in this exhibit was omitted and filed separately with the Securities and Exchange Commission pursuant to a confidential treatment request under Rule 24B-2 of the Securities Exchange Act of 1934, as amended.
     
+14
 
Code of Ethics for Principal Executive and Senior Financial Officers effective as of December 31, 2004. (Filed as Exhibit 14 to the company’s Form 10-KSB dated March 31, 2005 and incorporated herein by reference.)
 
 
 
+21
 
List of subsidiaries of the company (Filed as Exhibit 21 to the company’s Form 10-K for the year ended December 31, 2002 and incorporated herein by reference.)
 
 
 
*31.1
 
Certification of Principal Executive Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.
 
 
 
*31.2
 
Certification of Principal Financial Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.
 
 
 
*32.1
 
Certification of Principal Executive Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
 
 
 
*32.2
 
Certification of Principal Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
 
+ Incorporated by Reference.
 
* Filed herewith.
101