X0101 EFFECT 33 LIVE 2017-04-21 14:00:00

N-14

0000754915 T. Rowe Price High Yield Fund, Inc. 333-216513 0000754915 T. Rowe Price High Yield Fund, Inc. S000057617 T. Rowe Price U.S. High Yield Fund C000183993 T. Rowe Price U.S. High Yield Fund-Advisor Class 0001141306 HENDERSON GLOBAL FUNDS S000040218 Henderson High Yield Opportunities Fund C000125004 Class A 0000754915 T. Rowe Price High Yield Fund, Inc. S000057617 T. Rowe Price U.S. High Yield Fund C000183993 T. Rowe Price U.S. High Yield Fund-Advisor Class 0001141306 HENDERSON GLOBAL FUNDS S000040218 Henderson High Yield Opportunities Fund C000125005 Class C 0000754915 T. Rowe Price High Yield Fund, Inc. S000057617 T. Rowe Price U.S. High Yield Fund C000183994 T. Rowe Price U.S. High Yield Fund-I Class 0001141306 HENDERSON GLOBAL FUNDS S000040218 Henderson High Yield Opportunities Fund C000125006 Class I 0000754915 T. Rowe Price High Yield Fund, Inc. S000057617 T. Rowe Price U.S. High Yield Fund C000183994 T. Rowe Price U.S. High Yield Fund-I Class 0001141306 HENDERSON GLOBAL FUNDS S000040218 Henderson High Yield Opportunities Fund C000163667 Class R6