Income Taxes - Additional Information (Detail) - USD ($)	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021
Income Tax Disclosure [Line Items]
Valuation allowance, deferred tax assets	$ 61,531,000	$ 52,291,000
Research and development tax credit carryforwards	27,721,000	29,619,000
Accrued interest	4,585,000	4,184,000	$ 3,474,000	$ 3,246,000
Net interest expense	36,000	23,000	$ 17,000
Potential payment of interest	52,000	67,000
Stock-based compensation	$ 8,613,000	$ 5,709,000
Domestic Tax Authority [Member]
Income Tax Disclosure [Line Items]
Federal net operating loss carryforwards expiry, beginning year	2039
Research and development tax credit carryforwards	$ 12,344,000
Net operating loss carryforwards	$ 0
Certain States [Member]
Income Tax Disclosure [Line Items]
Federal net operating loss carryforwards expiry, beginning year	2025
Research and development tax credit carryforwards	$ 21,892,000
State and Local Jurisdiction [Member]
Income Tax Disclosure [Line Items]
Federal net operating loss carryforwards expiry, beginning year	2030
Net operating loss carryforwards	$ 4,000