Note 15 - Licenses of Intellectual Property and Patents (Details Textual)	12 Months Ended
	Dec. 31, 2017 USD ($) shares	Dec. 31, 2016 USD ($) shares	Jan. 31, 2003 USD ($) shares
Number Of Days Before Issuance Factoring Into Average Closing Price	20 days
Amount of Time after Effective Date of License Agreement for Registration Rights to Take Place	1 year
Common Stock, Shares, Issued | shares	17,277,299	2,230,452	253,691
Common Stock, Value, Issued | $	$ 172,772	$ 22,305	$ 2,200,000
Number Of Trademark Protection Application Pending For Thermo Dox	14