XML 49 R35.htm IDEA: XBRL DOCUMENT v3.8.0.1
Note 13 - Warrants (Tables)
 12 Months Ended
Dec. 31, 2017
Notes Tables  
Schedule of Warrant Activity [Table Text Block]
Warrants
  
Number of
Warrants
Issued
    
Weighted
Average
Exercise
Price
  
Warrants outstanding at
January 1, 2016
    
421,015
     $
58,88
  
Warrants issued in connection with 2016 equity transactions
    
1,147,595
     $
2.03
  
Warrants exercised during 2016
    
(17,857
)
   $
0.14
  
Warrants expired during 2016
    
(62,795
)
   $
209.23
  
Warrants outstanding at December 31, 2016
    
1,487,958
     $
9.39
  
Warrants issued in connection with 2017 equity transactions
    
9,231,628
     $
3.46
  
Warrants exercised during 2017
    
(7,617,147
)
   $
2.89
  
Warrants expired during 2017
    
(44,037
)
   $
174.58
  
Warrants outstanding at December 31, 2017
    
3,058,402
     $
5.29
  
                 
Aggregate intrinsic value of outstanding warrants at December 31, 201
7
   $
37,143
      
 
  
                 
Weighted average remaining contractual terms (years)
    
3.5