Note 7 - Other Accrued Liabilities (Tables)

12 Months Ended

Dec. 31, 2017

Notes Tables

Schedule of Accrued Liabilities [Table Text Block]

	Year Ended December 31,
	201 7		201 6
Amounts due to contract research organizations and other contractual agreements	$	665,373	$	1,115,193
Accrued payroll and related benefits		1,258,265		1,066,751
Accrued professional fees		264,668		259,550
Accrued interest on notes payable		-		22,241
Other		94,521		20,021
Total	$	2,282,827	$	2,483,756